Senior Scientist II, Analytical R&D

ZipRecruiter; North Chicago (IL); On-site; USD 90,000 - 120,000; Full time

Job summary

A leading company in the pharmaceutical sector is seeking a Senior Scientist II to drive innovative research in Analytical R&D. The role involves method development, project leadership, and collaboration across teams to enhance the pipeline of medicines. Ideal candidates will have a strong background in analytical chemistry and experience with chromatographic methods. This position offers the opportunity to contribute to significant scientific advancements and publications.

Qualifications

• Minimum 4 years of industry experience with a Ph.D. in Analytical Chemistry.
• Strong analytical background with method development experience.

Responsibilities

• Support high-throughput platform screening for separation-based assays.
• Develop stability-indicating methods using various analytical separation techniques.
• Lead analytical aspects of projects, collaborating with cross-functional teams.

Skills

Analytical Chemistry

Problem Solving

Chromatography

Education

Bachelor’s in Analytical Chemistry

Master’s in Analytical Chemistry

Ph.D. in Analytical Chemistry

Tools

HPLC

Chromatographic Modeling Software

Spectroscopic Techniques

Job description

Job Description

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn, and TikTok.

About AbbVie Analytical R&D

AbbVie Analytical Research & Development (Analytical R&D) is a global analytical scientific organization responsible for all CMC analytical activities related to the development of AbbVie's pharmaceutical products. Our scope includes a diverse pipeline of small molecule and therapeutic biologic medicines, from discovery to late-stage clinical development. We are building a world-class team of scientists and leaders to advance analytical capabilities and contribute to our pipeline of innovative medicines. Careers in AbbVie Analytical R&D offer opportunities to work with global, cross-functional teams to drive scientific and product development excellence. We seek diverse candidates with strong scientific backgrounds to join our team.

Position Description

We are seeking a highly motivated Senior Scientist II who can conceive, implement, and execute novel scientific research and development. The candidate will generate new scientific proposals, lead efforts, and act as a lead scientist in their area of expertise, critically evaluating scientific and regulatory advances for integration into research and development programs.

This role is within Analytical R&D’s Screening Lab, which focuses on high-throughput method screening and development supporting pipeline programs. The ideal candidate will have experience in chromatographic method development for small molecules and biologics, with hands-on experience in troubleshooting challenging separations, and an understanding of early-phase development of NCEs and NBEs.

Additional desirable experience includes project leadership in pharma, development of novel approaches for method development, advanced CDS control, process chromatography, automation, and emerging drug modalities (LNPs, peptides, oligos, etc.).

Responsibilities

1. Support high-throughput platform screening for separation-based assays (Chiral, Achiral, HILIC, SFC, 2DLC, HIC, IEX, SEC).
2. Develop stability-indicating methods using various analytical separation techniques (HPLC/UHPLC) and detection modes (UV, MS, CAD).
3. Utilize chromatographic modeling software (Fusion, Drylab, Chromsword) for method development and robustness.
4. Apply analytical separation techniques for impurity profiling to understand manufacturing processes.
5. Perform assay qualifications to establish method specificity, sensitivity, linearity, precision, robustness, and accuracy.
6. Lead analytical aspects of projects, collaborating with cross-functional teams to advance pipeline candidates.
7. Conduct R&D studies on small-molecule APIs, intermediates, starting materials, impurities, and formulations.
8. Communicate and collaborate across departments.
9. Evaluate and incorporate novel technology approaches, building scientific reputation through pipeline contributions and scholarly output.
10. Contribute to publications, presentations, and patents.

Qualifications

• Bachelor’s, Master’s, or Ph.D. in Analytical Chemistry with a minimum of 12 (BS), 10 (MS), or 4 (Ph.D.) years of industry experience.
• Strong analytical chemistry background with excellent problem-solving skills; able to develop and troubleshoot methods independently.
• Hands-on experience with HPLC analysis and method development; familiarity with spectroscopic techniques.
• Understanding of chromatography fundamentals and properties.
• Experience with computerized data systems.
• Knowledge of organic chemistry, functional groups, and modern spectroscopic techniques as applied to small molecules.

Additional Information

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Conclusion

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