Senior Scientist I, Pipeline Technology Enablement

SmartRecruiters, Inc.; North Chicago (IL); On-site; USD 97,000 - 184,000; Full time

Job summary

AbbVie in Lake County, Illinois, is seeking a Senior Scientist I to join a growing cancer research organization. The role focuses on discovering and validating novel cancer targets, driving discovery programs, and leading laboratory initiatives.

You will develop and optimize innovative genomic and cell-based high-throughput methods and play a key role in cross-functional collaboration. The candidate should have substantial post-graduate experience in oncology-related biology, expertise in NGS,

Qualifications

• PhD/MD or equivalent in a relevant bioscience field with extensive post-graduate experience.
• Experience in oncology translational research and cell biology.
• Strong publication and/or patent history.
• Proficiency in coding (R, Python) and advanced data analysis methods.

Responsibilities

• Develop novel functional genomics and high-throughput cellular technologies.
• Optimize high-throughput NGS workflows for deconvolution of pooled assays.
• Lead discovery programs and supervise junior scientists as needed.
• Publish internal reports and present at external meetings.
• Interpret large-scale datasets to guide research decisions.
• Mentor scientists and collaborate across diverse teams.

Skills

R

Python

NGS data analysis

CRISPR/Cas9

Cell biology

Genomics

Data analysis

Education

Bachelors, Masters or PhD in Cell/Molecular Biology, Biochemistry, Genetics/Genomics, Pharmacology, Oncology

Tools

NGS workflows

CRISPR/Cas9 tools

Robotic workstations

Job description

Senior Scientist I, Pipeline Technology Enablement

• Full-time
• Salary Min: 96500
• Salary Max: 183500
• Workday Global Grade: 17
• Compensation: USD 96,500 - USD 183,500 - yearly

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.

AbbVie is at the forefront of cancer research, discovering and developing the next generation of treatments to address unmet medical need for cancer patients. Our robust pipeline includes both small molecule and biologic therapies, featuring first-in-class agents that target multiple pathways critical to the survival and growth of solid and hematological malignancies.

We are seeking a highly motivated Senior Scientist I at AbbVie's Lake County, Illinois location to join our growing cancer research organization. The scientist will join a team focused on discovering and validating novel cancer targets, driving discovery programs, and leading laboratory-based initiatives. They will propose, develop, and optimize innovative methods, act as the lead in their area of expertise, and critically assess scientific and regulatory developments to integrate into research and development efforts.

Responsibilities:

• Develop and implement novel functional genomics and cell-based high-throughput technologies (pooled and arrayed).
• Develop and optimize high-throughput, reproducible NGS workflows for the sensitive deconvolution and quantification of pooled cellular assays.
• Lead and conduct scientific research of early-stage discovery programs.
• Resolve key project hurdles with available information from literature and internal experts.
• Possess excellent skills in scientific writing for internal reports, external presentations, and publications in peer-reviewed journals.
• Analyze, integrate, and interpret large-scale, high-dimensional datasets to drive strategic research decisions.
• May mentor/supervise scientists and evaluate their performance.
• Bachelors, Masters, or PhD in Cell/Molecular Biology, Biochemistry, Genetics/Genomics, Pharmacology, Oncology or a related field, with typically 0+ (PHD), 8+ (MS), or 10+ (BS) years post-graduate experience. Experience must be in cell/molecular biology, oncogenic pathways, cell death signaling, and/or translational research in Oncology.
• Extensive experience in NGS workflow implementation, cell engineering, oncology, drug discovery, and/or translational research is preferred.
• Impactful research experience as demonstrated by track record of publications, patents and/or scientific accomplishments is essential, as is the ability to engage internal and external scientific leaders in collaborative research.
• Proficiency in coding (e.g. R, python, etc.) and advanced data analysis techniques, including computational tools and statistical methods, to handle complex, high-dimensional scientific datasets.
• Experience generating and troubleshooting pooled cell line NGS assays (e.g., 384-well format)
• Experience in building workflows with external CROs.
• Hands-on experience with CRISPR/Cas9 gene editing using RNPs (and other equivalent approaches) to generate edited clonal cell lines and cell pools, including gene knockouts, knock-ins, point mutations, and fluorescent tagging.
• Experience implementing high-throughput pooled cell line assays and perturbations to generate expansive, information-rich datasets.
• Experience preparing large-scale sample sets for NGS using automated robotic workstations, gel electrophoresis, and amplicon PCR, along with Python-based analysis of gene editing outcomes.
• Demonstrated ability to manage and mentor junior scientists in technical lab skills, data organization, work efficiency, and scheduling.
• Ability to work collaboratively across diverse disciplinary environments.
• Strong written and oral communication skills are essential.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.