Senior Scientist I - Pharmacology

ABBVIE; North Chicago (IL); On-site; USD 97,000 - 184,000; Full time

Job summary

AbbVie’s Translational Sciences group seeks an In Vivo Imaging Scientist to lead preclinical PET imaging studies spanning rodents to large animals. You’ll work within Neuroscience Discovery Research to strengthen PET radioligands and translational endpoints for neurodegenerative, movement, and psychiatric programs.

You will coordinate multiple imaging studies, operate Mediso PET/CT systems, process plasma samples, analyze data, and develop robust protocols in a collaborative, cross-functional

Qualifications

• PhD in neuroscience, pharmacology, biomedical engineering, or a related field with typically 0-2 years of experience, or master’s degree or equivalent education with typically up to 8 years of experience.
• Demonstrated skills in preclinical PET imaging.
• Ability to execute deadlines in multidisciplinary teams and deliver high quality data.
• Good publication record in international peer reviewed journals.
• Capacity to work effectively in multidisciplinary teams.
• Track record of successful collaborations/building partnerships.
• Pharmaceutical industry experience preferred.
• Excellent analytical and problem-solving skills.
• Excellent oral and written communication skills.

Responsibilities

• Function as the study coordinator of several preclinical imaging studies.
• Provide experimental support for preclinical PET imaging studies in rodents and large animals (e.g., formulation and administration of radiotracer/contrast agent/compound, image data acquisition, and blood sampling).
• Operate various imaging systems, including a Mediso LFER 150 PET/CT and aMedisoNanoscanPET/CT.
• Handling & processing of plasma samples for, e.g., radiometabolite analysis via HPLC.
• Perform analysis of imaging data using specialized software.
• Develop and ensure high quality study protocols.
• Ensure maintenance of imaging equipment, in close collaboration with vendor support team.
• Communicate key results to team members and project stakeholders and contribute to study reports/publications.

Skills

Preclinical PET imaging

Multidisciplinary teamwork

Analytical skills

Publication record

Education

PhD in neuroscience/pharmacology/biomedical engineering or related field

Master's degree or equivalent with up to 8 years of experience

Tools

Mediso LFER 150 PET/CT

MedisoNanoscanPET/CT

Job description

• Compensation: USD 96,500 - USD 183,500 - yearly

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.

Job Description

The TranslationalSciencesgroup, within Neuroscience Discovery Research,is actively engaged in an innovative research programdedicated to identifying and strengthening biomarkers and translational endpoints to support AbbVie’s therapeutic programs. Workingacross theNeuroscience portfolio, with assetsin neurodegeneration, movement disorders, psychiatry, and migraine,our comprehensive approach includes discovering and developing novelpositron emission tomography (PET)radioligands,andtheir application(along with knownradioligands)in drug discovery and development.

Within Translational Sciences the Molecular Imaging team leads pre-clinicalandtranslational imaging activities working closelywith other groups in AbbVie (e.g., medicinal chemists, biologists, pharmacologists, and clinicians), leading academics, and CROs. The responsibility of the InVivo Imaging Scientist will be to lead and conduct preclinical PET imaging studies. The candidate will have access to state-of-the-art instrumentation and the opportunity to work with novel PET radioligands, animal models, and therapeutic drug approaches. This role operates in a collaborative culture and requires a high degree of matrix working both within the imaging function and across research departments.

Major Responsibilities:

Function as the study coordinator of several preclinical imaging studies.

Provide experimental support for preclinical PET imaging studies in rodents and large animals (e.g., formulation and administration of radiotracer/contrast agent/compound, image data acquisition, and blood sampling).

Operate various imaging systems, including a Mediso LFER 150 PET/CT and aMedisoNanoscanPET/CT.

Handling & processing of plasma samples for, e.g., radiometabolite analysis via HPLC.

Perform analysis of imaging data using specialized software.

Develop and ensure high quality study protocols.

Ensure maintenance of imaging equipment, in close collaboration with vendor support team.

Communicate key results to team members and project stakeholders and contribute to study reports/publications.

Qualifications

PhD in neuroscience, pharmacology,biomedical engineering,or a related field with typically 0-2years of experience, or master’s degree or equivalent education with typically up to 8years of experience.

Demonstrated skills in preclinical PET imaging.

Ability to execute deadlines in multidisciplinary teams and deliver high quality data.

Good publication record in international peer reviewed journals.

Capacity to work effectively in multidisciplinary teams.

Track record of successful collaborations/ building partnerships.

Pharmaceutical industry experience preferred.

Excellent analytical and problem-solving skills.

Excellent oral and written communication skills.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof thisp osting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.

We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.

This job is eligible toparticipatein our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paid andmay bemodifiedat the Company’s sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: