Associate Director / Principal Scientist I, Precision Medicine Immunology

AbbVie Inc.; Waltham (MA); Hybrid; USD 150,000 - 190,000; Full time

Job summary

AbbVie in Massachusetts (Waltham) is seeking an experienced translational and biomarker scientist with immunology expertise to lead translational activities in support of the immunology clinical development portfolio. You will develop and execute biomarker strategies, oversee assay validation, data management, and interpretation, and coordinate cross-functional teams with Medical Affairs, Regulatory, and external CROs.

This role demands strong communication and a track record of publication.

Qualifications

• Strong background in immunology with publication record.
• Experience in translational sciences and biomarker development.
• Familiarity with assay validation and data management.

Responsibilities

• Lead translational biomarker strategies for clinical programs.
• Coordinate sample management and data review with CROs.
• Oversee budgets, timelines, and regulatory considerations.
• Collaborate with Medical Affairs and other functions.
• Prepare clinical study reports and regulatory submissions.

Skills

Immunology expertise

Translational biomarker leadership

Biomarker data analysis

Team leadership

Scientific publication track record

Education

PhD/MD/PharmD with 4+ years

MS with 6+ years

BS with 10+ years

Tools

Biomarker assay techniques

Flow cytometry

IHC/IF

Gene expression profiling

Job description

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

Job Description

The Precision Medicine Immunology group is hiring an experienced translational and biomarker scientist with expertise in immunology who will be responsible for the development, planning, execution, and interpretation of translational precision medicine activities in support of the immunology clinical development portfolio at AbbVie.

Responsibilities

• Lead or co-lead the development and implementation of translational and biomarker strategic plans for one or more clinical programs. Responsibility may extend from early translational development activities to mature product life cycle strategies and back translational activities
• Manage the design, conduct, interpretation, and reporting of biomarker data/activities in line with the development, regulatory, and commercial strategies
• Lead asset-specific translational projects/teams in a matrix environment.
• Work with internal Operations group to coordinate activities such as sample management, technical validation of assays both internally and at external CROs, review of SOWs, and data management
• In collaboration with appropriate stakeholders ensure that clinical translational budgets, timelines, publication strategies, and regulatory compliance requirements are incorporated into program strategy
• Author and review all translational medicine aspects of clinical and regulatory documents including development plans, study protocols, clinical study reports, and regulatory submissions.
• Lead scientific collaborations and therapeutic area key opinion leader interactions in collaboration with partners from Medical Affairs, Commercial, or other functions.
• Proactively consult primary scientific literature, keep current on state of art technologies and emerging concepts in immunology.

Qualifications

• Principal Scientist I: PhD, PharmD and/or MD with 4+ years, MS with 6+ years, or BS with 10+ years of experience in the pharmaceutical industry or equivalent; substantial understanding of translational and precision medicine science required. Will hire at level according to experience.
• Associate Director: PhD, PharmD and/or MD with 6+ years or MS with 8+ years of experience in the pharmaceutical industry or equivalent; substantial understanding of translational and precision medicine science required. Will hire at level according to experience.
• Strong scientific background in immunology or related field supported by publication record in these areas
• Demonstrated leadership in translational sciences (employing pharmacodynamic, predictive and exploratory biomarkers) and experience with development of assays including ligand binding assays, IHC/IF, gene expression profiling, or flow cytometry is a plus
• Familiarity with data management and visualization tools and collaborating with computational biology to analyze complex data sets emerging from clinical trials
• Expertise in dermatology highly desirable
• Knowledge of clinical trial methodology, regulatory requirements governing clinical trials, companion diagnostics, protocol design, and/or experience in development strategy preferred.
• Ability to manage clinical translational programs and teams with moderate supervision.
• Excellent written and oral communication skills, ability to present results in a clear and concise manner, strong organizational skills with attention to detail, and effective time management with an ability to adapt to changing priorities
• Strong interpersonal and collaboration skills to work in a team-oriented, matrix environment, and the ability to work through conflicts

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible toparticipatein our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paid andmay bemodifiedat the Company’s sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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