Senior Scientist I, Mass Spectrometry

AbbVie Inc; North Chicago (IL); On-site; USD 70,000 - 110,000; Full time

Job summary

An innovative firm is seeking a highly motivated individual to join their Analytical Research & Development team. This exciting laboratory-based role involves designing and implementing advanced analytical methods for peptide and oligonucleotide characterization, focusing on mass spectrometry techniques. The successful candidate will collaborate with cross-functional teams to support early-phase drug development, showcasing their expertise in analytical chemistry. If you are a detail-oriented professional with a passion for scientific discovery and innovation, this is the perfect opportunity to make a significant impact in a dynamic environment.

Benefits

Paid Time Off

Medical Insurance

Dental Insurance

Vision Insurance

401(k) Plan

Short-Term Incentive Programs

Qualifications

• Experience in mass spectrometry for peptide and oligonucleotide characterization.
• Strong analytical chemistry background with problem-solving skills.

Responsibilities

• Utilize mass spectrometry techniques for drug product characterization.
• Develop and implement novel analytical methods for pharmaceuticals.

Skills

Mass Spectrometry

Analytical Chemistry

Problem-Solving Skills

Peptide Characterization

Biophysical Characterization

Education

Bachelor in Chemistry

Master in Biochemistry

Ph.D. in Chemistry

Tools

LC-MS

High-Resolution MS

Data Handling Systems

Job description

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

Job Description

The Analytical Research & Development team is seeking a talented, highly motivated candidate with experience in the characterization of peptide and oligonucleotide biomolecules. This is a laboratory-based role, and the successful candidate will be responsible for designing, developing, and implementing analytical methods for the characterization of peptides and oligonucleotides with an emphasis on mass spectrometry-based methods. Candidate should possess an understanding of their core discipline and use that expertise to support early phase development of drug substance and drug product and collaborate across the global Analytical R&D organization and with cross-functional partners such as Pre-Clinical Safety (PCS), Process Chemistry, Process Engineering, Drug Product Development (DPD), Quality Assurance (QA), and CMC-Regulatory.

Responsibilities:

• Utilize cutting-edge mass spectrometry techniques, including high-resolution MS, MS/MS, ion mobility-MS, and 2DLC-MS, to characterize small molecule, peptide, and oligonucleotide drug products, active pharmaceutical ingredients, intermediates, starting materials, and impurities.
• Identify, develop, and implement novel analytical methods for the characterization of peptide and oligonucleotide pharmaceuticals with an emphasis on LC-MS and biophysical characterization to drive discovery projects through the research and development pipeline.
• Be responsible for leading the structure elucidation aspects of a project while collaborating with cross-functional project teams to advance programs through the development pipeline.
• Support new product development with advanced method development and validations, technical transfer packages, and generation of technical data in support regulatory requirements.
• Be highly autonomous and productive in performing laboratory research or method development, requiring only minimal direction from or interaction with supervisor.
• Formulate conclusions and design follow-on experiments based on multidisciplinary data.
• Initiate new areas of investigation that are scientifically meaningful, reliable, and can be incorporated directly into a research and development program.
• Communicate and collaborate with cross-functional groups and departments.
• Routinely demonstrate scientific initiative and creativity in research or development activities and maintain a high level of productivity in the lab.

Qualifications

• Bachelors, Masters, or Ph.D. in Chemistry, Biochemistry, or closely related field typically with minimum 10 (BS), 8 (MS), or 0-2 (Ph.D.) years related industry experience.
• Extensive experience in designing mass spectrometry experiments for the characterization of peptides, proteins, and/or oligonucleotides and a strong understanding of instrument theory and operation.
• Strong technical background in analytical chemistry, excellent analytical problem-solving skills. Capable of independently developing and troubleshoot analytical methods.
• Practical knowledge of organic structure, functional groups, chemistry, biochemistry, and modern spectroscopic and biophysical characterization techniques.
• Experience or knowledge of peptide synthesis approaches a plus.
• Self-motivated, hard-working, detail-oriented individual able to work in a fast-paced team environment.
• Experience in the use of computerized data handling systems.
• High-quality written and oral communication skills and ability to interact effectively with interdisciplinary scientists and engineers.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees.

• This job is eligible to participate in our short-term incentive programs.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html