Senior Scientist I, LC-MS/MS Small Molecule In Vitro/In Vivo Bioanalysis

Allergan; North Chicago (IL); On-site; USD 85,000 - 110,000; Full time

Job summary

A leading company in North Chicago is seeking a Senior Scientist I to support drug discovery through quantitative LC-MS/MS bioanalysis. The role involves conducting analyses, maintaining instrumentation, and collaborating with teams to develop novel assays. Ideal candidates will have a strong background in analytical chemistry and experience with LC-MS/MS platforms.

Benefits

Paid Time Off

Medical/Dental/Vision Insurance

401(k) Plan

Short-term Incentive Programs

Qualifications

• PhD with 0-4 years, M.S. with 8+ years, or BS with 10+ years in analytical chemistry.
• Strong background in LC-MS/MS bioanalysis and method development.
• Experience with high-throughput LC-MS/MS platforms.

Responsibilities

• Perform quantitative LC-MS/MS analysis for PK/PD studies.
• Operate and maintain LC-MS/MS instrumentation.
• Investigate and implement new methodologies and technologies.

Skills

Analytical Chemistry

LC-MS/MS Method Development

Problem Solving

Communication

Education

PhD

M.S.

BS

Tools

Sciex API-6500

Sciex Analyst

Hamilton

Tecan Dispenser

Job description

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onX,Facebook,Instagram,YouTube,LinkedInandTik Tok.

Job Description

The Non-Regulated Bioanalysis group in the Quantitative, Translational & ADME Sciences Department at AbbVie has an open position for a Senior Scientist I position in North Chicago, IL to perform small molecule and peptide bioanalysis supporting drug discovery and development. The successful candidate will be responsible for independently conducting quantitative LC-MS/MS bioanalysis in support of in-vivo PK/PD/TK studies, along with providing insight and answering technologic or key scientific questions to collaborators and junior scientists.

Responsibilities:

• Perform quantitative LC-MS/MS analysis of small molecules and peptides to provide bioanalytical support for PK/PD, efficacy, and exploratory toxicology studies meeting customer satisfaction and project timelines.
• Routinely operate LC-MS/MS instrumentation, including maintenance, troubleshooting, identification and resolution of instrument and assay problems.
• Investigate, evaluate, and implement new methodologies, platforms, and technologies to meet challenging assay requirements and throughput while maintaining effective resource utilization.
• Serve as scientific interface and close partner to other teams for bioanalysis support and development/operationalization of novel assays.
• Maintain electronic laboratory notebooks (ELN) and manage study documentation in the Laboratory Information Management System (LIMS).
• Write or contribute to study reports for regulatory submissions.

Qualifications

• PhD (0-4years), M.S. (8+ years) or BS (10+ years) in analytical chemistry or related field with relevant academic or industry experience.
• Strong LC-MS/MS method development background with direct experience in bioanalysis/assays and understanding of both experimental design and analytical practices required.
• Expertise with current high-throughput LC-MS/MS platforms (e.g., Leap autosamplers, Sciex API-6500/7500 triple quadrupoles), software (e.g., Sciex Analyst and/or OS, Electronic notebooks, LIMS, Discovery Quant) and automated sample preparation (e.g., Hamilton, Tecan Dispenser) platforms.
• Working experience in regulated bioanalysis and/or CRO/University Core facility settings will be a plus.
• Excellent personal, verbal, and written communication skills.
• Highly organized with keen attention to detail, enabling effective independent work and success within a matrix team environment.
• Desire to excel in a fast-paced environment, with strong problem-solving skills, and the ability to prioritize tasks and meet deadlines effectively.

Key Leadership Competencies:

• Build strong relationships with peers and cross functionally with partners outside of the immediate team to enable higher performance, proven ability to collaborate successfully across other groups within R&D.
• Creates a learning environment, open to suggestions and experiments to drive science in the field of interest.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality, learns fast, grasps the “essence” and can change course quickly when needed.
• Raises the bar and is never satisfied with the status quo.
• Highly motivated and self-driven with the flexibility to quickly adapt to different projects.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes ingood faith it will pay for this role at the time of this posting based on the job grade for this position. Individualcompensation paid within this range will depend on many factors including geographic location, and we may ultimatelypay more or less than the posted range. This range may be modified in the future.

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/visioninsurance and 401(k) to eligible employees.

• This job is eligible to participate in our short-term incentive programs.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, and determinable.The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefitsthat are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid andmay be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html