Senior Scientist I, Biologics In Vitro Technologies

American Society for Biochemistry and Molecular Biology (ASBMB); Worcester (MA); On-site; USD 80,000 - 120,000; Full time

Job summary

A leading company in the biopharmaceutical sector is seeking an accomplished scientist to join their Biologics Discovery Sciences Group. The ideal candidate will lead antibody discovery strategies and collaborate in a dynamic research environment. This role offers the opportunity to develop innovative approaches and drive significant projects across various therapeutic areas, requiring strong expertise in molecular biology and exceptional collaboration skills.

Benefits

Paid time off (vacation, holidays, sick)

Medical/dental/vision insurance

401(k) Plan

Participation in short-term incentive programs

Qualifications

• PhD, MS, or BS in Biochemistry with required years of experience.
• Hands-on experience with in vitro antibody discovery technologies.
• Recognized in the scientific community through publications.

Responsibilities

• Implement novel selection strategies for therapeutic candidates.
• Design and execute engineering requests for candidate optimization.
• Present original work at scientific conferences.

Skills

Molecular biology

Antibody engineering

Collaboration

Organizational skills

Presentation skills

Education

PhD in Biochemistry or related discipline

MS in Biochemistry or related discipline

BS in Biochemistry or related discipline

Tools

Flow cytometry

Geneious

PipeBio

Job description

ICompany Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

The Biologics Discovery Sciences Group at AbbVie is seeking an accomplished scientist to contribute significantly to the conception, execution, and communication of antibody discovery strategies in a highly collaborative environment. The successful candidate will develop and execute research strategies to advance the discovery and development of therapeutic antibodies for AbbVie's core therapeutic areas. Key responsibilities include designing and executing in vitro display technologies for lead antibody identification and optimization. The candidate is also expected to generate internal and external collaborations to further program goals and drive antibody discovery programs within a multidisciplinary research group in a dynamic, fast-paced team setting.

Key Responsibilities:

• Implement novel selection strategies and build industry-leading libraries for discovery and screening of therapeutic candidates
• Design, strategize, and execute on engineering requests to further develop, optimize, and progress candidates through the pipeline
• Identify and solve technical problems; independently, conceive and implement innovative research ideas
• Leverage expertise to develop and implement research to gain a detailed mechanistic understanding of the molecular pharmacology of therapeutic molecules
• Provide project updates, analyses and advice to cross-functional teams and senior management
• Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents
• Ensure consistency and quality of technical reports
• Ability to engage internal and external scientific leaders in collaborative research
• Serve as a biologics lead for cross-functional teams, and contribute scientific insights into multiple projects across various therapeutic areas; recognized and sought out as an expert in discovery and engineering of therapeutic molecules

Qualifications

• PhD, MS, or BS degree in Biochemistry, Biochemical engineering or related disciplines with typically 0+ (PhD), 8+ (MS), or 10+ (BS) years of experience
• Hands-on experience with in vitro antibody discovery display technologies (e.g., phage, yeast, mammalian)
• Experience and up-to-date knowledge in antibody engineering and optimization best practices
• Antibody/antibody fragment library design and construction
• Strong molecular biology skills
• Familiarity with sequence analysis tools (Geneious, PipeBio)
• Experience with flow cytometry
• Ability to explore and develop new approaches to further advance innovative in vitro discovery, screening, and engineering technologies
• Excellent organizational skills and the ability to manage multiple projects simultaneously
• Team player with the ability to operate in a fast-paced multi-disciplinary environment with functional and therapeutic areas
• Adapt to rapid changes in project priorities and timelines
• Recognized in the scientific community through a record of peer-reviewed publications and patents preferred
• Highly developed leadership and communication skills
• Keen ability to engage internal and external scientific leaders in collaborative research

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.htmlI