Senior Scientist, High-Throughput RNA Production

Sail Biomedicines; Cambridge (MA); On-site; USD 75,000 - 95,000; Full time

Job summary

Sail Biomedicines is seeking a Senior Research Associate for high-throughput RNA production to advance Endless RNA™ technology. You will perform end-to-end RNA generation from template cloning to IVT, manage materials, and help optimize workflows in a fast-paced environment.

The role emphasizes meticulous documentation, teamwork, and strong problem-solving to support real-world patient impact, with a competitive salary and benefits package.

Qualifications

• B.S. in Life Sciences, Chemistry, Engineering, or a related field with 2+ years of relevant full-time industry or academic research experience, or M.S. in Life Sciences
• Ability to manage multiple tasks at once efficiently
• Strong collaborative spirit and communication skills
• Excellent record keeping
• Experience with RNA production and purification is preferred
• Experience with automated liquid handling systems and high-throughput workflows is preferred

Responsibilities

• Perform high-throughput cloning of plasmid constructs and RNA generation through in vitro transcription (IVT)
• Determine circularization efficiency and impurity levels by running analytic assays
• Coordinate DNA synthesis and scale-up orders with external vendors
• Manage raw material and RNA inventories
• Collaborate with automation engineer to improve process workflow
• Maintain detailed documentation in electronic lab notebooks
• Present findings clearly to platform teams and contribute to scientific discussions and decision-making

Skills

Task management

Collaboration & communication

Documentation skills

Education

B.S./M.S. in Life Sciences/related field

Tools

Excel

Benchling

SnapGene

Graphic Prism

HPLC

Hamilton (automation)

Job description

Sail Biomedicines is seeking a Senior Research Associate for high-throughput RNA production to advance Endless RNA™ technology. You will perform end-to-end RNA generation from template cloning to IVT, manage materials, and help optimize workflows in a fast-paced environment.

The role emphasizes meticulous documentation, teamwork, and strong problem-solving to support real-world patient impact, with a competitive salary and benefits package.