Senior Scientist, High-Throughput Experimentation

myGwork - LGBTQ+ Business Community; Lower Gwynedd Township (Montgomery County); On-site; USD 90,000 - 140,000; Full time

Job summary

A leading healthcare company is seeking a Senior Scientist for High-Throughput Experimentation. This role involves designing automated experiments and collaborating across functions to drive innovative drug discovery. The candidate must have a strong background in chemistry and proven experience in high-throughput environments.

Qualifications

• Minimum 4 years of relevant experience.
• Experience in high-throughput chemistry workflows preferred.
• Ability to work cross-functionally.

Responsibilities

• Design and execute automated experiments.
• Collaborate with various functions to accelerate discovery.
• Streamline workflows and develop automated processes.

Skills

Analytical skills

Problem-solving skills

Communication skills

Organizational skills

Education

Bachelor's degree in Chemistry

Master's degree or PhD

Tools

Python

SQL

Automated synthesis platforms

Job description

Senior Scientist, High-Throughput Experimentation

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Senior Scientist, High-Throughput Experimentation

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This job is with Johnson & Johnson, an inclusive employer and a member of myGwork – the largest global platform for the LGBTQ+ business community. Please do not contact the recruiter directly.

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented, treated, and cured,where treatments are smarter and less invasive, andsolutions are personal.Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.Learn more at https://www.jnj.com

Job Function

Discovery & Pre-Clinical/Clinical Development

Job Sub Function

Chemical Research

Job Category

Scientific/Technology

All Job Posting Locations:

Spring House, Pennsylvania, United States of America

Job Description

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Senior Scientist, High-Throughput Experimentation to be located in Spring House, PA.

Purpose: We are seeking a highly motivated Senior Scientist to join our High-Throughput Experimentation (HTE) Center of Excellence within Global Discovery Chemistry (GDC). This unique role provides an unprecedented opportunity to contribute to the impact of our state-of-the-art capabilities on Johnson & Johnson's evolving pipeline and to further innovation in the high-throughput technologies space.

In GDC, we deliver high quality drug candidates in close partnership with all Johnson & Johnson Therapeutic Area (TA) discovery teams. The successful scientist will join a team consisting of chemists with a diversity of skills including Medicinal Chemistry, Automated Synthesis, Computational Chemistry, Cheminformatics, Data Science, Analytical Chemistry etc. They will use state-of-the art techniques and instrumentation to design and synthesize drug candidates to advance drug discovery projects across a range of modalities. Acceleration of discovery programs through application of high-throughput experimentation, high-throughput synthesis, reaction automation and AI/ML approaches will be a focus.

You Will Be Responsible For

• Designing and executing automated experiments to optimize chemical reactions or discover new transformations that impact progression of discovery leads.
• Designing and performing HTE experiments to generate reaction data to fuel synthesis prediction efforts and AI/ML models applicable to J&J's internal programs.
• In close collaborations with partners across other functions (i.e., Biochemistry, Pharmacology, Data science), contributing to the evolution and application of our Direct-to-Biology (D2B) platform by designing, validating and completing semi-automated and automated experiments to effectively accelerate the discovery portfolio and Design-Make-Test-Analyze cycles.
• Designing and executing semi-automated and automated experiments to effectively carry out structure-activity relationships (SAR) campaigns on drug discovery projects.
• Identifying broad implications of data including data capture and data mining from HTE and parallel experiments.
• Streamlining workflows and developing automated laboratory processes.
• Becoming an expert in high-throughput synthesis workflows in J&J and provide training to Global Discovery Chemistry team members on HTE and D2B workflows when necessary.
• Learning programming and debugging with Python, Pipeline Pilot, relational databases, SQL, LIMS or other relevant enterprise software packages.
• Proactively and clearly providing project status updates to key partners, through various channels including in-person and virtual meetings.
  
  

Education

Qualifications / Requirements:

• A minimum of a Bachelor's degree in Chemistry or a related field is required. An advanced degree (Master's, PhD) is preferred.
  
  

Experience And Skills

Required:

• At least 4 years of relevant experience (e.g., PhD, post-doc, industry experience with automated synthesis workflows) is required.
• The ability to work in a cross-functional environment with a can-do attitude to drive productivity and efficiency is required.
• Strong organization and communication skills, independence, strong analytical and problem-solving skills are required.
• Excellent written and interpersonal skills with strong relationship management abilities. is required.
• Ability to maintain a very productive lab presence is required.
  
  

Preferred

• Experience in high-throughput chemistry workflows (e.g., parallel synthesis, high-throughput experimentation, direct-to-biology) is preferred.
• Proficiency in coding and data science tools is preferred.
• Experience with operating automated synthesis platforms (e.g., Chronect Quantos, Tecan, UnChained Labs, Mosquito/DragonFly etc.) is preferred.
• Extensive experience with multi-dimensional data analysis tools, including Spotfire or equivalent is preferred.
  
  

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center ([e-mail]) or contact AskGS to be directed to your accommodation

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

• Industries

  Hospitals and Health Care

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