Senior Scientist, Genomics & Viral Vector Engineering

Amgen; Thousand Oaks (CA); On-site; USD 150,000 - 190,000; Full time

Benefits offered by this job

Retirement and Savings Plan

Group medical, dental, vision coverage

Life and disability insurance

Flexible spending accounts

Discretionary annual bonus program

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models

Job summary

Amgen is seeking a Senior Scientist in Functional Genomics to advance viral vector platforms and genome engineering for therapeutic target discovery. You will work within the TD&B group to design, engineer, and characterize AAV and lentiviral vectors, enabling in vitro and in vivo CRISPR perturbation studies.

You will collaborate with multidisciplinary teams to translate innovative technologies into biologically meaningful discoveries that drive the next generation of therapeutics.

Qualifications

• Doctorate degree in a relevant field or equivalent postdoctoral/industrial experience.
• Master's degree with 3 years of scientific experience or a Bachelor's with 5 years experience.
• Demonstrated expertise in genome engineering, viral vectors, and functional genomics.

Responsibilities

• Develop and implement next-generation viral vector platform and genome engineering technologies.
• Design, engineer, produce, optimize, and characterize AAV and lentiviral vectors for genetic perturbation applications in vitro and in vivo.
• Design and execute molecular biology and functional genomics experiments to support target discovery and validation.
• Interpret experimental data and communicate findings to multidisciplinary discovery teams.
• Evaluate emerging technologies to enhance discovery capabilities in genome and viral vector engineering.
• Collaborate with biology, computational biology, chemistry, and therapeutic teams to solve complex problems.

Skills

Molecular biology

Genome engineering

CRISPR technologies

Functional genomics

AAV vectors

Lentiviral vectors

Molecular cloning

Construct design

Genetic tools

Experimental design

Data analysis

Communication

Collaboration

Scientific creativity

Education

Doctorate degree in Molecular Biology, Cell Biology, Genetics, Bioengineering, Virology, or related discipline

Master's degree with 3 years of scientific experience

Bachelor's degree with 5 years of scientific experience

Tools

AAV vectors

Lentiviral vectors

Job description

Amgen is seeking a Senior Scientist in Functional Genomics to advance viral vector platforms and genome engineering for therapeutic target discovery. You will work within the TD&B group to design, engineer, and characterize AAV and lentiviral vectors, enabling in vitro and in vivo CRISPR perturbation studies.

You will collaborate with multidisciplinary teams to translate innovative technologies into biologically meaningful discoveries that drive the next generation of therapeutics.