Senior Scientist - Gastroenterology (Hepatology)

Washington University; Northern (KY); Hybrid; USD 63,000 - 115,000; Full time

Benefits offered by this job

Vacation & Holidays

Health insurance

Metro U-Pass

403(b) Retirement Savings

Tuition assistance

Caregiver leave

Job summary

Washington University in St. Louis' Schwartz Laboratory in the Division of Gastroenterology seeks motivated and creative scientists to join an interdisciplinary program studying HBV biology and mechanisms of chronic infection, with the goal of identifying strategies toward a functional cure.

Our lab develops human infection models using stem cell-derived hepatocytes, primary hepatocytes, CRISPR, and HBV clones.

Qualifications

• Education: Phd Or Terminal Degree Or Combination Of Education And Experience May Substitute For Minimum Education.
• Certifications/Professional Licenses: No specific certification/professional license is required for this position.
• Work Experience: Postdoctoral (3 Years)
• Skills: Not Applicable
• Driver's License: A driver's license is not required for this position.

Responsibilities

• Collaborates on designing, conducting and reporting of research projects.
• Assists with grant preparation and reporting.
• May submit grant proposals in rare circumstances with the approval of the PI, Department Head and Dean.
• Prepares and submits papers on research.
• Develops hypotheses to be tested and ways of testing it.
• Complies with established safety procedures and maintains required documentation on laboratory and specimen conditions.
• Manages research project with other institutions and investigators.
• Perform other duties as assigned.

Skills

Analytical Problem Solving

Laboratory Instrumentation

Laboratory Processes

Laboratory Techniques

Oral Communications

Teamwork

Working Independently

Written Communication

Education

Phd Or Terminal Degree Or Combination Of Education And Experience May Substitute For Minimum Education

Job description

Location SAINT LOUIS, MO 63110 Scheduled Hours 40

Position Summary

The Schwartz Laboratory in the Division of Gastroenterology, Department of Medicine, at WashU Medicine in St. Louis is seeking motivated and creative scientists to join our interdisciplinary research program investigating the biology of hepatitis B virus (HBV) and the mechanisms that allow the virus to establish and maintain chronic infection. Our long-term goal is to understand the complex interactions between HBV and its host that drive viral persistence and to use these insights to identify new strategies toward a functional cure for chronic hepatitis B, which remains a major global health challenge and an important cause of liver related morbidity and mortality. Our laboratory has a strong history of developing innovative human models of viral infection. We were among the first groups to establish hepatitis B and hepatitis C virus infection models using stem cell-derived hepatocytes, and we have continued to combine these systems with primary human hepatocytes, CRISPR/Cas9 gene editing, and genetically distinct HBV clones to dissect the host and viral factors that determine infection and persistence. Recent work from the laboratory, published in Cell, identified a nucleosome-level molecular switch that primes and influences HBV infection (10.1016/j.cell.2025.01.033). Collaborates on designing, conducting and reporting of research projects.

Job Description

• Collaborates on designing, conducting and reporting of research projects.
• Assists with grant preparation and reporting.
• May submit grant proposals in rare circumstances with the approval of the PI, Department Head and Dean.
• Prepares and submits papers on research.
• Develops hypotheses to be tested and ways of testing it.
• Complies with established safety procedures and maintains required documentation on laboratory and specimen conditions.
• Manages research project with other institutions and investigators.
• Perform other duties as assigned.

Working Conditions

Works in a laboratory environment with potential exposure to biological, chemical and radioactive hazards. Must be physically able to wear protective equipment and to provide standard care to research animals. The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Required Qualifications

Education: Phd Or Terminal Degree Or Combination Of Education And Experience May Substitute For Minimum Education.

Certifications/Professional Licenses: No specific certification/professional license is required for this position.

Work Experience: Postdoctoral (3 Years)

Skills: Not Applicable

Driver's License: A driver's license is not required for this position.

Preferred Qualifications

Education: No additional education unless stated elsewhere in the job posting.

Certifications/Professional Licenses: No additional certification/professional licenses unless stated elsewhere in the job posting.

Work Experience: No additional work experience unless stated elsewhere in the job posting.

Skills: Analytical Problem Solving, Laboratory Instrumentation, Laboratory Processes, Laboratory Techniques, Oral Communications, Teamwork, Working Independently, Written Communication

Grade R12 Salary Range

$63,400.00 - $115,000.00 / Annually

Questions for Frequently Asked Questions About the Application Process

Please refer to our External Applicant FAQ.

Accommodation

If you are unable to use our online application system and would like an accommodation, please email [e-mail] or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request. All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

Pre-Employment Screening

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement

• Personal Up to 22 days of vacation, 10 recognized holidays, and sick time.
• Competitive health insurance packages with priority appointments and lower copays/coinsurance.
• Take advantage of our free Metro transit U-Pass for eligible employees.
• WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
• Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
• Family We offer 4 weeks of caregiver leave to bond with your new child.
• Family care resources are also available for your continued childcare needs.
• Need adult care? We’ve got you covered.
• WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
• For policies, detailed benefits, and eligibility, please visit https://hr.wustl.edu/benefits/.

EEO Statement

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.

Useful Links

• Who We Are
• Human Resources
• Benefits
• Living in St. Louis
• Frequently Asked Questions
• Accommodation If you are unable to use our online application system and would like an accommodation, please email [e-mail] or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
• Regulatory Postings Know Your Rights: Workplace Discrimination is Illegal Poster (English; Spanish)