Senior Scientist, Antibody Discovery & Phage Display

Xairatherapeutics; South San Francisco (CA); On-site; USD 124,000 - 155,000; Full time

Benefits offered by this job

Equity

Competitive compensation

Job summary

Xaira Therapeutics in the San Francisco Bay Area is seeking a seasoned protein biochemist to own phage display campaigns end-to-end within the Display Technologies group, designing selection strategies and turning campaigns into high-quality data for antibody design models.

This high-ownership role emphasizes rigorous bench execution, experimental design, mentoring, and collaboration with computational and engineering teams to scale data generation.

Qualifications

• PhD in Molecular Biology, Biochemistry, Immunology, Protein Engineering, or related field.
• 2–4 years of relevant industry experience.
• Hands-on antibody/protein discovery by phage display with hit validation.

Responsibilities

• Independently design, execute, and own phage display campaigns from library through panning and hit validation.
• Develop and optimize selection strategies for challenging targets; QC and use of antigens across formats.
• Collaborate with ML teams to structure and QC data at scale for model training.
• Mentor associate scientists and contribute to technical standards.

Skills

Phage display

Flow cytometry (FACS)

Experimental design

Mentoring

Scientific communication

Education

PhD in Molecular Biology, Biochemistry, Immunology, Protein Engineering, or related field

Tools

SPR

Python

R

Automation platforms (Hamilton/Tecan)

Job description

Xaira Therapeutics in the San Francisco Bay Area is seeking a seasoned protein biochemist to own phage display campaigns end-to-end within the Display Technologies group, designing selection strategies and turning campaigns into high-quality data for antibody design models.

This high-ownership role emphasizes rigorous bench execution, experimental design, mentoring, and collaboration with computational and engineering teams to scale data generation.