Senior Scientist, Analytical Development & QC (Hybrid/Remote)

Ionis Brand; Carlsbad (CA); Hybrid; USD 114,000 - 150,000; Full time

Job summary

Ionis Pharmaceuticals, Inc. in Carlsbad, CA, seeks a Senior Scientist to join Analytical Development & Quality Control (ADQC). The role emphasizes method development and validation across LC-MS, HPLC, and GC in a GMP setting, with independent, detail-oriented work and strong communication.

You will design experiments, document results for regulatory filings, and collaborate across teams to ensure quality and compliance. Must hold a Ph.D.

Qualifications

• Ph.D. in Analytical Chemistry or related discipline with at least 2 years of industry experience.
• Skilled in developing methods using LC-MS, HPLC, and GC.
• Practical knowledge of GMP requirements with hands-on GMP experience preferred.

Responsibilities

• Develop and validate analytical methods for Starting Materials and peptides
• Characterize new reference standards by a variety of analytical techniques
• Conduct routine and non-routine analysis of Raw and Starting Material samples
• Document and compile data for quality review
• Review data for compliance to specifications
• Conduct analytical investigations
• Author scientific reports and portions of the CMC section of regulatory filings
• Author SOPs as needed (e.g., analytical methods, equipment procedures, and material specifications)
• Present at internal and cross-functional scientific meetings

Skills

LC-MS

HPLC

GC

Analytical chemistry

GMP experience

Education

Ph.D. in Analytical Chemistry or related discipline

Job description

Ionis Pharmaceuticals, Inc. in Carlsbad, CA, seeks a Senior Scientist to join Analytical Development & Quality Control (ADQC). The role emphasizes method development and validation across LC-MS, HPLC, and GC in a GMP setting, with independent, detail-oriented work and strong communication.

You will design experiments, document results for regulatory filings, and collaborate across teams to ensure quality and compliance. Must hold a Ph.D.