Senior Scientist

Bristol-Myers Squibb Co; Harvard (MA); On-site; USD 123,000 - 149,000; Full time

Benefits offered by this job

Flexible Time Off

11 holidays

Paid vacation (160 hours)

Global shutdown

Job summary

Bristol Myers Squibb in Devens, MA seeks a Senior Scientist in the Scale-up Lab to lead upstream and downstream process development for the Biologics portfolio.

You will collaborate with process, analytical and manufacturing teams, support GMP activities, and drive tech transfer to clinical and commercial manufacturing while advancing new technologies.

Qualifications

• Ph.D. with 2–4 years or MS with 4–6 years or BS with 7–9 years in chemical/biochemical engineering.
• Strong knowledge of upstream or downstream processing.
• Working knowledge of cGMP.
• Excellent oral and written communication skills.
• Works well in a team and as an individual.
• Prior experience in single-use manufacturing and automation.
• Knowledge of statistics, design of experiment, and data analysis is desired.

Responsibilities

• Lead/support scale-up lab operations including bioreactor fill/harvest, inoculation, sampling, feeding, operating chromatographic and filtration skids.
• Prepare/review technical documents including campaign summary reports and batch records.
• Participate in cross-functional teams to support process investigations, process development, scale-up, and tech transfer to clinical and commercial manufacturing.
• Introduce, evaluate, and implement innovative new process technologies and capabilities.
• Identify and implement process transfer improvement initiatives with internal stakeholders.
• Support GMP-related activities for external manufacturing programs (as needed).
• Maintain a safe work environment in the Scale-up lab.

Skills

Upstream/Downstream processing

cGMP

Communication skills

Teamwork & independence

Single-use manufacturing & automation

Statistics & DOE

Education

Ph.D. in Chemical/Biochemical Eng or related

M.S. in Chemical/Biochemical Eng or related

B.S. in Chemical/Biochemical Eng or related

Job description

At Bristol Myers Squibb, our employees often ask, \"Who are you working for?\"- a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it. Bristol Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. One shared journey is moving us forward at Bristol-Myers Squibb. Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and ideas so that we can learn and grow together. And driven to make a difference, from innovative research to hands-on community support. Bristol-Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees the resources to pursue their goals, both at work and in their personal lives.

The Senior Scientist position will be part of the Scale-up Lab based in Devens, MA and reports to the Director of Pilot Plant Network and External Manufacturing (PPNE). The candidate will be responsible for scale-up and execution of upstream and downstream processes for all assets within the Biologics Development portfolio. The candidate will work closely with the process, analytical and manufacturing teams to improve internal process tech transfer procedures and collaborate on new technology initiatives. In addition, the individual will provide support (on as-needed basis) to external GMP-related activities (investigations, deviations, CAPA, change control) within BD's external portfolio. Prior experience with Pilot, Manufacturing or Biologics Process development is a plus.

Key Responsibilities

• Lead/support daily operations in the Scale-up Lab, including bioreactor fill/harvest, inoculation, sampling, feeding, operating chromatographic and filtration skids, buffer preparation, run monitoring/troubleshooting
• Prepare/review technical documents including campaign summary reports and batch records
• Participate in cross-functional teams to support process investigations, process development, scale-up, and tech transfer to clinical and commercial manufacturing
• Introduce, evaluate, and implement innovative new process technologies and capabilities
• Identify and implement process transfer improvement initiatives with internal stakeholders
• Support GMP-related activities for BD External Manufacturing programs (as needed)
• Maintain a safe work environment in the Scale-up lab
• Works with an operational excellence mindset

Qualifications

Ph.D. with 2-4 years experience, M.S. with 4-6 years experience or B.S. with 7-9 years experience in Chemical/Biochemical Engineering, Biochemistry, or related field with relevant industrial and/or academic experience.

• Strong knowledge of either Upstream Processing (Mammalian Cell Culture) or Downstream Processing (Harvest, Chromatography and Filtration)
• Working knowledge of cGMP
• Excellent oral and written communication skills
• Works well in a team and as an individual
• Prior experience in single-use manufacturing and automation
• Working knowledge of cGMP is a plus
• Knowledge of statistics, design of experiment, and data analysis is desired

Compensation Overview

Compensation Overview: Devens - MA - US: $123,120 - $149,196. The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully - carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits:

Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans - including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability). U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year. Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays. Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day. U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits

How We Work

How We Work Where you work matters - because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

Supporting People with Disabilities BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

Candidate Rights BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/ For roles based in Washington state only: If you live in or expect to work from Washington State if hired for this position, please visit this page for important information about the Washington Fair Chance Act.

Data Protection

Data Protection We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations. If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1607750 : Senior Scientist Data Privacy Link

We're creating innovative medicines for patients fighting serious diseases. We're also nurturing our own diverse team with inspiring work and challenging career options. No matter the role, each one of us makes a contribution. And that makes all the difference.