Senior Research Technician - Medical Oncology

Washington University in St. Louis; United States; Presencial; USD 26 000 - 44 000; Tempo integral

Vantagens oferecidas por esta oferta de emprego

Vacation and sick leave

Health insurance

Transit benefits

Retirement plan (403b)

Wellness programs

Caregiver leave

Tuition assistance

Resumo da oferta

Washington University in St. Louis is seeking a Senior Research Technician to contribute to translational cell therapy projects. The role involves developing and evaluating engineered immune cells (CAR-T) using CRISPR/Cas9 methods and preclinical models, with emphasis on IND-enabling work and clinical translation.

You will work under Dr. John DiPersio, reporting to Dr. Jerry Xiang, in a collaborative, well-resourced lab environment that supports professional growth and cross-disciplinary

Qualificações

• Master's degree or equivalent experience; lab setting experience preferred.
• Background in molecular/cellular biology; cancer biology or genomics preferred.
• Experience with mice and small animal procedures is a plus.
• Proficiency with standard lab techniques and data analysis.

Responsabilidades

• Performs complex analyses following research protocols and discusses methods with technicians.
• Enters and maintains data files; monitors data quality and performs basic statistics.
• Ensures compliance with safety procedures and documentation of conditions.
• Maintains lab conditions/equipment per procedures; assists training of technicians.
• Contributes to design and execution of experiments on engineered immune cells.
• Collaborates with multidisciplinary teams and supports translational goals.
• Performs other duties as assigned.

Conhecimentos

Molecular biology

Genomics

Mice handling

Flow cytometry

Cell culture

Protein biochemistry

Data analysis

Recordkeeping

Communication

Formação académica

Master's degree

Ferramentas

CRISPR/Cas9

Descrição da oferta de emprego

Location SAINT LOUIS, MO 63110

Scheduled Hours 40

Position Summary A Senior Research Technician position is available in the laboratory of Dr. John DiPersio, with direct reporting to Dr. Jerry Xiang. This position is part of a translational cell therapy program focused on advancing next‑generation immunotherapies from discovery through IND-enabling studies and clinical translation. The successful candidate will work at the interface of discovery and translation, contributing to projects involving CRISPR/Cas9 gene‑edited CAR-T cell therapy for hematologic malignancies. Ongoing efforts are directed toward IND‑enabling studies, providing a unique opportunity to gain hands‑on experience in developing cell therapies from bench to clinic. Will assist in developing and supporting the design and execution of experiments, including the generation and functional evaluation of engineered immune cells in preclinical mouse models. This role involves close collaboration with multidisciplinary teams and offers the chance to contribute meaningfully to projects with direct clinical impact. Our group is highly collaborative and offers a supportive, well‑resourced setting with strong opportunities for professional growth.

Job Description

Primary Duties & Responsibilities:

• Performs complex analysis/projects according to research protocols, explaining methods and procedures to other technicians.
• Enters data and maintains current data files on research projects.
• Monitors data to ensure consistent quality.
• May perform preliminary statistical analysis of data.
• Assures compliance with established safety procedures and maintains required documentation on laboratory and specimen conditions.
• Ensures lab conditions and equipment are properly cleaned and maintained in accordance with established procedures.
• Assists in the training and development of technicians, acting as a group leader.
• Performs other duties as assigned.

Working Conditions

Works in a laboratory environment with potential exposure to biological and chemical hazards. Must be physically able to wear protective equipment and to provide standard care to research animals.

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Required Qualifications

Education: Master's degree or combination of education and/or experience may substitute for minimum education. Certifications/Professional Licenses: No specific certification/professional license is required for this position. Work Experience: Laboratory Setting (1 Year) Skills: Not Applicable Driver's License: A driver's license is not required for this position.

Preferred Qualifications

Self-motivated candidates with a solid background in molecular and cellular biology, preferably with knowledge and prior experience in cancer biology and/or genomics. Previous work experience with mice is preferred, including handling, injections, and other small animal procedures. Proficient with standard laboratory techniques including cell culture, protein biochemistry, and flow cytometry. Prior experience in basic or translational lab settings. Ability to effectively communicate and collaborate with others is essential. Ability to perform, troubleshoot, and analyze experimental data. Excellent record-keeping and organizational skills. Effective verbal, written, and interpersonal communication skills. Ability to prioritize workload.

Preferred Qualifications Education: No additional education unless stated elsewhere in the job posting. Certifications/Professional Licenses: No additional certification/professional licenses unless stated elsewhere in the job posting. Work Experience: No additional work experience unless stated elsewhere in the job posting. Skills: Communication, Laboratory Instrumentation, Recordkeeping, Software Program, Working Independently.

Salary

Grade R08-H Salary Range $18.77 - $31.94 / Hourly The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement

• Personal Up to 22 days of vacation, 10 recognized holidays, and sick time.
• Competitive health insurance packages with priority appointments and lower copays/coinsurance.
• Take advantage of our free Metro transit U-Pass for eligible employees.
• WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
• Wellness Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
• Family We offer 4 weeks of caregiver leave to bond with your new child.
• Family care resources are also available for your continued childcare needs.
• Need adult care? We've got you covered.
• WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.

For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/

Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity or shared ancestry, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information. As a federal contractor, the university maintains affirmative action programs to implement its equal employment opportunity policy for individuals with disabilities and protected veterans, in accordance with Section 503 of the Rehabilitation Act of 1973, as amended, and the Vietnam Era Veterans’ Readjustment Assistance Act of 1974 (VEVRAA), as amended.

Washington University in St. Louis' collective success is significantly attributed to the passion and outstanding efforts of our community. Our staff, faculty and trainees are committed to excellence and dedicated to carrying out our missions of research, teaching and patient care. WashU prides itself on being a place where people matter, and serious work is done. Our people work together in an inclusive community that celebrates diverse perspectives, collaboration and innovation. We are a community of individuals inspired to work together to develop big ideas and tackle challenging problems. We value the well-being of our people. WashU strives to create a positive employee experience where staff, faculty and trainees thrive, both personally and professionally. Our employees find meaning, connection and vitality in their work and life with a healthy work-life balance and support to learn, grow and make an impact at WashU, the community and the world.