Senior Research Technician, Integrated Genomics Operation

Memorial Sloan Kettering Cancer Center; New York (NY); On-site; USD 44,000 - 68,000; Full time

Job summary

Memorial Sloan Kettering Cancer Center is seeking a Research Assistant for the Integrated Genomics Operation (IGO) in NYC. You will extract nucleic acids from diverse biomaterials, perform QA/QC, and train on cutting-edge spatial transcriptomics methods.

The role requires clean benchwork, strong attention to detail, and collaboration across teams. You will work with ddPCR techniques to validate oncogenic changes, maintain precise records in LIMS, and communicate with vendors while supporting

Qualifications

• Bachelor’s degree in biology, chemistry, or related field with at least 2 years of experience or Master’s degree.
• Experience purifying nucleic acids for NGS platforms and working with FFPE samples is valued.

Responsibilities

• Extract nucleic acids from a variety of biomaterials (fresh frozen, FFPE, cell lines, blood, plasma, serum, etc.).
• Perform QA/QC of extracted material.
• Train on spatial transcriptomic methods from 10x Genomics platforms.
• Learn design and execution of ddPCR experiments for validating oncogenic alterations.
• Work with team to create LEAN workflows.
• Interact with vendor technical support and sales representatives.
• Operate liquid handlers and robotic instruments for high-throughput processing.
• Maintain accurate records in a Laboratory Information Management System (Examplar Sapio LIMS).
• Use iLAB for billing purposes.

Skills

Nucleic acid purification

NGS platforms

Digital PCR

Spatial transcriptomics

Liquid handling robots

Data management

Communication skills

LEAN principles

Vendor interfacing

Education

Bachelor’s degree in biology, chemistry, or related field

Master’s degree

Tools

Examplar Sapio LIMS

iLAB for billing

Job description

About Us:

The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursueour missionat MSK and around the globe.

Exciting opportunity at MSK: Join our Integrated Genomics Operation (IGO) as a Research Assistant! The Integrated Genomics Operation (IGO) enables basic, clinical and translational research projects across the Cancer Center. Ultimately, the focus of our work is to help establish the basis of cancer pathogenesis, diagnostics and treatment at MSKCC. At the IGO, we implement the MSK mission to cure cancer by providing a broad range of genomic services and expertise to our world‑class research scientists. We are a high‑throughput core facility producing >100TB of data per year across >40 applications, including “fourth generation” genomics technologies such as single cell and spatial transcriptomics.

You will master a variety of genomics assays utilizing either robotics or traditional benchwork; and will interface with other teams within the IGO. As a full‑service genomics lab, we provide high level expertise to the scientists and physicians at our institution.

Role Overview:

• Extract nucleic acids from a variety of biomaterial (fresh frozen and formalin‑fixed paraffin embedded tissue, cell line, blood, plasma, serum, saliva, nails, etc).


• Perform quality assurance and quality control of extracted material.


• Train on cutting‑edge spatial transcriptomic methods from 10x genomics platforms.


• Learn the theory, design and execution of droplet digital PCR experiments, traditionally used to validate oncogenic alterations with a high degree of sensitivity and accuracy.


• Work with your team to create a workflow following LEAN principles.


• Communicate with vendor technical support and sales representatives.


• Operate liquid handlers and robotic instruments for high‑throughput processing.


• Maintain accurate and detailed records in a Laboratory Information Management System (Examplar Sapio LIMS).


• Use iLAB for billing purposes.

Key Qualifications:

• Bachelor’s degree in biology, chemistry, or related field with at least 2 years of experience or Master’s degree.


• Previous exposure to purifying nucleic acids for NGS platforms, knowledge of digital PCR, and experience with cells and FFPE samples is highly valued.

Core Skills:

• Exceptional attention to detail and strong analytical skills.


• Ability to thrive in a fast‑paced research environment, managing multiple projects while maintaining precision. Enthusiastic about learning opportunities in the lab.


• Critical thinking and problem‑solving skills to troubleshoot experimental challenges.


• Outstanding interpersonal and communication skills and the ability to interact across all levels in a confident, concise, and professional manner.


• Comfortable with manual or automated processing.


• Enthusiasm and dedication to MSK's vision, mission, and values.

Additional Information:

• Location: NYC


• Schedule: Onsite, Monday to Friday

Helpful Links:

• Compensation Philosophy


• Benefits

Pay Range: $32.10 - $49.79FSLA Status: Non-Exempt

Closing

At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills.

MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.

Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.