Manager, Research and Development – Integrated Genomics Operation

Memorial Sloan Kettering Cancer Center; United States; On-site; USD 103,000 - 165,000; Full time

Job summary

Memorial Sloan Kettering Cancer Center (MSK) is seeking a Manager, Research and Development for the Integrated Genomics Operation to lead the R&D group and guide the development of cutting-edge genomic assays.

You will supervise technicians, design and optimize high-throughput genomics workflows, and ensure rigorous documentation while partnering with production teams and internal stakeholders to translate assays from concept to scalable services in a fast-paced cancer research environment.

Qualifications

• PhD in Molecular Biology, Biochemistry, or a related discipline.
• Minimum of 3 years of postdoctoral experience in an academic research environment.
• Hands-on experience with experimental and computational genomics methodologies.
• Strong publication record in NGS assay development.
• Excellent written, verbal, and interpersonal communication skills.

Responsibilities

• Lead IGO’s R&D group and supervise technicians focused on testing and developing new genomics technologies.
• Design, evaluate, and optimize novel assays, including feasibility assessments and protocol development.
• Maintain detailed experimental records, technical documentation, and written summaries of research activities.
• Identify anomalies in experimental data and resolve root causes through systematic troubleshooting.
• Partner with IGO production teams to transition validated assays into efficient, high-throughput services.
• Mentor team members, evaluate performance, and provide timely feedback.
• Communicate scientific concepts clearly in lab meetings, cross-functional forums, and seminars.
• Contribute creatively to problem-solving while considering operational and business aspects of a core facility.

Skills

Genomics technologies

Leadership

Analytical thinking

Communication

Education

PhD in Molecular Biology, Biochemistry, or related discipline

Job description

About Us

The people of Memorial Sloan Kettering Cancer Center (MSK) are united by a singular mission: ending cancer for life. Our specialized care teams provide personalized, compassionate, expert care to patients of all ages. Informed by basic research done at our Sloan Kettering Institute, scientists across MSK collaborate to conduct innovative translational and clinical research that is driving a revolution in our understanding of cancer as a disease and improving the ability to prevent, diagnose, and treat it. MSK is dedicated to training the next generation of scientists and clinicians, who go on to pursueour missionat MSK and around the globe.

Exciting Opportunity

The Integrated Genomics Operation (IGO) at MSK is seeking a Manager, Research and Development to lead the evaluation, development, and implementation of cutting‑edge genomics technologies. IGO is a high‑throughput core facility that enables basic, clinical, and translational cancer research by providing world‑class genomic services and expertise to MSK investigators. The team generates more than 100TB of data annually across 40+ genomic applications, including next‑generation approaches such as single‑cell and spatial transcriptomics. This is an outstanding opportunity for an experienced molecular biologist to combine scientific innovation, people leadership, and operational excellence in support of MSK’s mission to cure cancer.

Role Overview

As the Manager, Research and Development, you will lead IGO’s R&D group and play a critical role in bringing novel genomic assays from concept to scalable, high‑throughput production. Leading and supervising a team of technicians focused on testing and developing new genomics technologies. Designing, evaluating, and optimizing novel assays, including feasibility assessments and protocol development. Maintaining detailed experimental records, technical documentation, and written summaries of research activities. Identifying anomalies in experimental data and resolving root causes through systematic troubleshooting. Partnering closely with IGO production teams to transition validated assays into efficient, sustainable, high‑throughput services. Collaborating with internal and external stakeholders, including data analysts and scientific partners. Mentoring team members, evaluating performance, and providing timely, constructive feedback. Communicating scientific concepts clearly and effectively in lab meetings, cross‑functional forums, and institutional seminars. Contributing creatively to problem‑solving while maintaining an appreciation for the operational and business aspects of a core facility.

Key Qualifications

• PhD in Molecular Biology, Biochemistry, or a related discipline
• Minimum of 3 years of postdoctoral experience in an academic research environment
• Hands‑on experience with experimental and computational genomics methodologies
• Strong publication record in NGS assay development
• Excellent written, verbal, and interpersonal communication skills

Core Skills

• Advanced expertise in molecular biology and genomics technologies.
• Strong analytical and problem‑solving abilities with exceptional attention to detail.
• Ability to prioritize and adapt quickly in a dynamic environment.
• Proven people‑leadership and mentorship capabilities.
• Collaborative mindset with the ability to build strong cross‑functional relationships.
• Clear, adaptable communication style for diverse scientific and non‑scientific audiences.
• Consistent delivery of high‑quality results, even under ambitious circumstances.

Additional Information

• Schedule: On‑Site, Monday – Friday, 37.5 hrs.
• Location: 1250 First Avenue, New York, NY (Schwartz)
• Reporting to: Integrated Genomics Operation (IGO) Leadership

Helpful Links

Compensation Philosophy Benefits Pay Range: $102,800.00 - $164,500.00 FSLA Status: Exempt Closing: At MSK, we believe in fair, competitive pay that reflects your job, experience, and skills. MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision. Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment. Our multi‑disciplinary teams work together to provide exceptional patient care, develop innovative research, and deliver outstanding educational programs. Learn More The people of MSK make this an incredible place to work, grow and make a difference. Discover what makes us unique