Senior Research Scientist

Massachusetts General Hospital; Boston (MA); On-site; USD 70,000 - 113,000; Full time

Job summary

Massachusetts General Hospital's Wainger Laboratory seeks a Senior Scientist to lead translational research at the intersection of neurodegenerative diseases, stem cell biology, functional genomics, and computational biology.

The role uses human tissue analyses, patient-derived iPSC neurons, and multi-omics pipelines to identify therapeutic targets, with collaboration across the Healey Center for ALS, Broad Institute and Harvard Medical School.

Qualifications

• PhD/Doctorate in a related field required.
• 5–7 years of academic or laboratory research experience.
• Strong publication and collaboration capabilities.

Responsibilities

• Lead translational research in neurodegenerative disease areas.
• Develop and apply multi-omic pipelines and computational analyses.
• Supervise technical staff and students/postdocs.
• Publish findings and present at reputable conferences.

Skills

Computational biology

Experimental design

Data analysis

Team leadership

Communication

Education

Doctorate in related field

Job description

Site: The General Hospital Corporation

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

The Wainger Laboratory at Massachusetts General Hospital (MGH) is seeking a highly motivated, collaborative, and innovative Senior Scientist to lead high-impact translational research at the intersection of neurodegenerative diseases, stem cell biology, functional genomics, and computational biology.

The successful candidate will leverage human postmortem tissue analyses, patient-derived induced pluripotent stem cell (iPSC) neuron models, and advanced bioinformatics/multi-omic pipelines to systematically discover, prioritize, validate, and develop novel therapeutic targets. This role offers an exceptional opportunity to work within a deeply translational environment closely aligned with the Healey Center for ALS at MGH, Broad Institute, and Harvard Medical School.

Independently carries out a broad range of technically advanced research activities and procedures; conceives of and designs experiments, evaluates conclusions, and has complete latitude to modify or devise methods and techniques as necessary to achieve desired results; may supervise technical and administrative elements of research unit.

Essential Functions

• Function as a skilled scientific specialist for the research unit or for a specific research project.
• Conducts broad range of experiments or computational analyses involving advanced technology/strategies; conceives of the objective of research studies and designs experimental protocols/computational analyses to achieve the objectives; generates, analyzes and evaluates experimental data; interprets the results of experiments/computational analyses.
• Writes and edits material for publication; may present papers or appear as principal or secondary author in publications.
• Provides direct supervision to technical and support personnel as assigned.
• Provides instruction in laboratory or computational techniques and methodology to students and postdoctoral fellows.

Qualifications

Education

Doctorate Related Field of Study required

Can this role accept experience in lieu of a degree?

No

Experience

Experience in an academic or laboratory research setting 5-7 years required.

Knowledge, Skills And Abilities

• Proficiency in supply chain and vendor management.
• Ability to identify problems and troubleshoot solutions.
• Well-versed in laboratory standards and practices.
• Good organizational skills, detail-oriented.
• Sound degree of computer literacy.
• Ability to methodically record data.
• Good interpersonal and communication skills.
• Broad knowledge of scientific principles, biological structures, and laboratory techniques.

Additional Job Details (if Applicable)

$70,000 - $113,000.

Remote Type

Onsite

Work Location

114 16th Street

Scheduled Weekly Hours

40

Employee Type

Regular

Work Shift

Day (United States of America)

EEO Statement

1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.

Mass General Brigham Competency Framework

At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.