Senior Research Investigator, Clinical Pharmacology and Pharmacometrics

Bristol-Myers Squibb; Princeton (NJ); Hybrid; USD 80,000 - 130,000; Full time

Job summary

An established industry player is seeking a Clinical Pharmacologist to lead the design and execution of pharmacology studies. This role offers the opportunity to work on transformative projects that impact patient lives, collaborating with high-achieving teams in a dynamic environment. You will apply your expertise in pharmacokinetics and model-based analyses to support drug development while contributing to innovative strategies. If you are passionate about science and eager to make a difference, this position is your chance to thrive in a meaningful career.

Benefits

Competitive benefits

Flexible work environment

Career development opportunities

Qualifications

• 2+ years of experience in Clinical Pharmacology for Ph.D. or PharmD.
• 5-7 years of experience in Clinical Pharmacology for Master’s Degree.

Responsibilities

• Design and execute Clinical Pharmacology studies and manage data analysis.
• Collaborate on drug development strategies and regulatory submissions.

Skills

Pharmacokinetics/Pharmacodynamics principles

Model Informed Drug Development (MIDD)

Quantitative data analysis

Programming (NONMEM, R, WinNonlin, SAS, Monolix)

Strong written and oral communication

Team-oriented collaboration

Education

Ph.D. or PharmD

Master’s Degree

Tools

NONMEM

R

WinNonlin

SAS

Monolix

Job description

Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us .

The Clinical Pharmacology & Pharmacometrics Department are responsible for the Clinical Pharmacology characterization for small and large molecule assets across all therapeutic areas beginning with the entry in humans through registration and after commercial launch. The responsibilities encompass the development of clinical pharmacology plans that align with and complement the clinical development plans throughout all stages of development and includes the design and execution of clinical pharmacology studies along with conduct of model-based Population PK and exposure-response analysis to drive dose selection, characterization of DDI liabilities, implications for special populations, understanding the effects of formulation changes, as well as informing other critical drug development questions to influence company decisions. Furthermore, this department is responsible for representing Clinical Pharmacology at health authority interactions and compiling technical documents that are critical for worldwide submissions.

Position Summary / Objective

•Responsible for design and execution of Clinical Pharmacology activities and work on assigned projects.
•Leads, plans, and executes trial level activities and development of compounds while managing data analysis.
•Applies Pharmacokinetics/Pharmacodynamics principles and model-based analyses to support drug development.
•Collaborates within Clinical Pharmacology and cross-functionally to assist with functional development strategies.

Position Responsibilities
•Contribute to the development of compounds with some supervision
•Lead design of Clinical Pharmacology studies and manage data analysis, interpretation, and reporting
•Contribute to clinical development strategies of pipeline product
•Proficient in PK, PK/PD, and Model Informed Drug Development (MIDD) principles and analyses
•Acquires and interprets PK/PD
•Participate in interactions with health authorities
•Contribute to and/or lead modeling and simulation plans
•Collaborate on cross-functional drug development teams, regulatory submissions, and departmental

Experience Requirements

For Ph.D. or PharmD, approximately 2+ years’ experience with demonstrated progression in Clinical Pharmacology and Pharmacometrics knowledge, including knowledge of drug development process

For Master’s Degree, 5-7 years’ experience with demonstrated progression in Clinical Pharmacology and Pharmacometrics knowledge, including knowledge of drug development process.

Key Competency Requirements

· Knowledge of current practices and issues in Clinical Pharmacology and Pharmacometrics

· Strong written and oral communication skills necessary to report on and deliver scientific presentations

· Demonstrated ability to work in a dynamic team-oriented environment

· Serve as the CP&P lead for one or more assets in the BMS drug development program, with supervision

· Programming experience (e.g., NONMEM, R, and WinNonlin. SAS, Monolix, etc.)

· Quantitative data analysis, POP PK/PD, and data visualization skills

#LI-Hybrid

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail] . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

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