Senior Research Associate, Target Biology

Bayside Solutions; California (MO); On-site; USD 76,000 - 90,000; Full time

Job summary

Bayside Solutions, a leading staffing partner, seeks a Senior Research Associate for Target Biology in Redwood City, CA. Support early target discovery, screening, and validation for oncology programs in a dynamic, collaborative setting.

The role emphasizes hands-on mammalian cell culture, molecular biology techniques, and development of cellular assays within the Target Biology team of Discovery Biology.

Qualifications

• Bachelor's or Master's degree in molecular biology, biochemistry, biotechnology, or related field.
• 5+ years of industry experience in a cell biology/molecular biology role.
• Ability to think independently, interpret, and communicate results to team members and leadership.
• Extensive experience with mammalian cell culture techniques and manipulation of cells, including aseptic technique.
• Experience in microplate-based assay systems and operation of plate readers or microscopes.
• Experience in common data processing and visualization tools for data analysis (e.g., GraphPad Prism).
• Highly organized, with excellent record-keeping, problem-solving, and critical thinking skills.
• Excellent written and verbal communication skills for effective collaboration.

Responsibilities

• Plan, design, and execute in vitro cellular assays (2D/3D culture, nanoBRET, AlphaLISA) and related readouts.
• Engineer cell lines and establish cellular assay models.
• Maintain cultures of multiple cancer cell lines to support experiments.
• Generate high-quality data and maintain detailed records.
• Collaborate with cross-functional project teams to support early discovery.
• Present findings at meetings across departments.

Skills

Mammalian cell culture

Molecular biology

Data analysis

Team collaboration

Experimental design

Education

Bachelor's or Master's degree in molecular biology/biochemistry/biotechnology

Tools

GraphPad Prism

Plate readers

Microscopes

Job description

Senior Research Associate, Target Biology

W2 Contract

Pay Rate: $55 - $65 per hour

Location: Redwood City, CA - Onsite Role

Job Summary:

We are seeking a talented senior research associate with a strong background in molecular, cancer, and cell biology to support early target discovery, screening, and validation efforts for novel oncology programs. The successful applicant will join the Target Biology team within Discovery Biology. They will work closely with team scientists and utilize a wide array of cellular and molecular biology assays and develop reagents to support validation of novel targets for our unique molecular glue platform. The ideal candidate will have hands-on experience with mammalian cell culture and standard molecular biology techniques. They will participate in engineering new cell models and develop, optimize, and troubleshoot cellular assays. Above all, we are looking for a highly motivated, independent, and driven team player to join our diverse and talented team of scientists.

Duties and Responsibilities:

• Plan, design, and execute in vitro cellular assays (e.g., 2D and 3D cell culture, nanoBRET, AlphaLISA, and other plate-based assays, SDS-PAGE/western blot, qPCR, CRISPR-based gene editing) and implement relevant assay readout technologies.
• Engineer cell lines and establish cellular assay models.
• Maintain cultures of multiple cancer cell lines to support experimental efforts.
• Generate high-quality data in a timely manner and maintain detailed experimental records.
• Work with cross-functional project team members to support early discovery efforts.
• Regularly and effectively communicate findings at departmental and inter-departmental meetings.

Requirements and Qualifications:

• Bachelor's degree or Master's degree in molecular biology, biochemistry, biotechnology, or related field.
• 5+ years of industry experience in a cell biology/molecular biology role.
• Ability to think independently, interpret, and communicate results to team members and leadership.
• Extensive experience with mammalian cell culture techniques and manipulation of cells, including excellent aseptic technique.
• Experience in microplate-based assay systems and operation of plate readers or microscopes.
• Experience in common data processing and visualization tools for data analysis (e.g., GraphPad Prism).
• Highly organized, with excellent record-keeping, problem-solving, and critical thinking skills.
• Excellent written and verbal communication skills for effective collaboration with interdepartmental teams.
• An energetic and proactive team player with the ability to work efficiently in a dynamic company environment.

Preferred Qualifications:

• Viral transduction and CRISPR/Cas9 gene editing experience.
• Experience with automated liquid handling systems and workflows is preferred.
• Familiarity with cellular and biochemical readouts, including viability, immunofluorescence, MSD, and flow cytometry, is preferred.

Desired Skills and Experience

Molecular Biology, Cell Biology, Cancer Biology, Biochemistry, Biotechnology, Target Discovery, Target Screening, Target Validation, Oncology Drug Discovery, Discovery Biology, Molecular Glue Therapeutics, In Vitro Cellular Assays, Assay Development, Assay Optimization, Assay Troubleshooting, 2D Cell Culture, 3D Cell Culture, Mammalian Cell Culture, Cancer Cell Lines, Cell Line Engineering, Cellular Assay Models, Aseptic Technique, nanoBRET, AlphaLISA, Microplate-Based Assays, Plate Readers, Microscopy, SDS-PAGE, Western Blotting, qPCR, CRISPR/Cas9 Gene Editing, Viral Transduction, Automated Liquid Handling, Immunofluorescence, MSD Assays, Flow Cytometry, Cell Viability Assays, Biochemical Assays, Reagent Development, Data Analysis, Data Visualization, GraphPad Prism, Experimental Design, Experimental Documentation, Data Interpretation, Scientific Communication, Cross-Functional Collaboration, Problem-Solving, Critical Thinking, Bachelor's or Master's Degree, 5+ Years of Biotechnology or Pharmaceutical Industry Experience

Bayside Solutions, Inc. is not able to sponsor any candidates at this time. Additionally, candidates for this position must qualify as a W2 candidate.

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