Senior Research Associate, Flow Cytometry

Xtalks; Cambridge (MA); On-site; USD 95,000 - 115,000; Full time

Job summary

Beam Therapeutics is seeking a hands-on scientist in Cambridge, MA, to support internal and external research programs through flow cytometry and assay development. This role focuses on high-parameter analyses, cell sorting, data interpretation, and presenting results to the team.

You will operate and troubleshoot BD FACS platforms (Melody, Aria Fusion, Symphony S6), maintain electronic lab notebooks, and train colleagues in flow cytometry techniques while coordinating core lab logistics.

Qualifications

• Performing high-parameter flow cytometry analyses of hematopoietic stem and immune cell subsets.
• Designing and executing flow-based assay development for preclinical or translational research.
• Troubleshooting instrument performance and coordinating maintenance.

Responsibilities

• Supporting all internal/external research programs.
• Execute specimen preparation, staining and sample acquisition of flow cytometric data.
• Perform cell sorting on BD FACS Melody, FACSAria Fusion or BD FACS Symphony S6.
• Design, plan, and execute assay development and/or platform development within the core flow cytometry group and cross-functionally.
• Perform flow data analyses and interpretation, and present data at group meetings.
• Maintain electronic notebook record of performed experiments.
• Provide basic training to researcher on various flow cytometers and cell sorters.
• Evaluate and troubleshoot instrument issues.
• Assist in coordinating core lab logistics (e.g. user scheduling, vendor/maintenance calls, etc.)

Skills

Flow cytometry

Cell sorting

Data analysis

FlowJo

FCS Express

Education

Bachelor's degree with 5+ years or Master's with 2+ years in biology or related field

Tools

BD FACS Melody

FACSAria Fusion

BD FACS Symphony S6

Job description

Company Overview

Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam's suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases.

Company Overview

Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam's suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases.

Primary Responsibilities

• Supporting all internal/external research programs.
• Execute specimen preparation, staining and sample acquisition of flow cytometric data.
• Perform cell sorting on BD FACS Melody, FACSAria Fusion or BD FACS Symphony S6.
• Design, plan, and execute assay development and/or platform development within the core flow cytometry group and cross-functionally.
• Perform flow data analyses and interpretation, and present data at group meetings.
• Maintain electronic notebook record of performed experiments.
• Provide basic training to researcher on various flow cytometers and cell sorters.
• Evaluate and troubleshoot instrument issues.
• Assist in coordinating core lab logistics (e.g. user scheduling, vendor/maintenance calls, etc.)

Qualifications

• Bachelor's degree (or foreign equivalent) with five years of progressive, post-baccalaureate experience, or a master's degree (or foreign equivalent) with two years of progressive, post-baccalaureate experience, with degree fields in biology, immunology, cell biology, molecular biology, pharmaceutical sciences, biochemistry, biomedical engineering, biotechnology or a closely related field, and demonstrated experience in all of the following:
• performing high-parameter flow cytometry analyses of hematopoietic stem and immune cell subsets, and,
• designing and executing flow-based assay development for preclinical or translational research; and,
• conducting quantitative flow cytometry data analysis using FlowJo or FCS Express; and,
• troubleshooting instrument performance and coordinating maintenance; and,
• operating and maintaining high-parameter flow cytometers and cell sorters.

Other Information

• Permanent, full-time, immediately available, job opportunity;
• Does not require travel (role is substantially laboratory-based, in-house);
• Not permitted to telecommute, i.e., cannot exclusively work remotely from home;
• Must live in the City of Cambridge, MA, or within a reasonable, daily commuting distance thereof (e.g., areas contemplated can include the City of Boston, the larger Greater Boston region, or Massachusetts' MetroWest, North or South Shore communities);
• Beam's headquarters is at 238 Main Street, Cambridge, MA 02142 and this is the primary worksite for the role long-term; and
• Role is not a supervisory role and does not have subordinate, direct reports. This is a hands-on, individual contributor position.

The salary range below reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on several factors including, but not limited to, relevant experience, education, scope of job, internal comparisons, and market data.

Beam Pay Range

$95,000-$115,000 USD