Senior Research Associate, Biosensor Assay Development

allegromicro; Manchester (NH); On-site; USD 90,000 - 120,000; Full time

Job summary

Allegro MicroSystems in Manchester, NH is seeking a Senior Research Associate to join the new Molecular Sensors Laboratory, helping develop, validate, and scale our Giant Magnetoresistance (GMR) biosensor platform and multi-modal assay workflows for protein, DNA, and RNA detection.

The role emphasizes hands-on experimentation, collaboration across disciplines, and translating biological assays into robust sensor-based diagnostics to support product development and customer applications.

Qualifications

• Bachelor's or Master's in Biochemistry, Molecular Biology, Bioengineering, Chemistry, or related field.
• 3–6 years hands-on lab experience in biotech/diagnostics/R&D environments.
• Experience with biosensor assays and biomolecule handling.
• Strong data analysis and problem-solving abilities.
• Proficiency with Excel; JMP or Python desirable.

Responsibilities

• Execute and optimize biosensor assays across targets and sample matrices.
• Develop surface functionalization and bioconjugation workflows for sensors.
• Analyze results with Excel/JMP/Python and communicate findings to stakeholders.
• Support lab operations and ensure safety and quality compliance.
• Collaborate with engineers to integrate assay requirements into system design.

Skills

Experimental design

Data analysis

Troubleshooting

Communication

Education

Biochemistry / Molecular Biology / Bioengineering

Tools

Excel

JMP

Python

Job description

The Allegro team is united by a clear purpose-advancing technologies that make the world safer, more efficient, and more sustainable. With over 30 years of experience in semiconductor innovation, we bring that purpose to life across every part of the business-from breakthrough product development and customer success to how we show up for each other and the communities we serve.

The Opportunity

Allegro MicroSystems is building a pioneering team at the intersection of semiconductor technology and life sciences. We are seeking a highly motivated Senior Research Associate to become a foundational member of our new Manchester Molecular Sensors Laboratory .

Working closely with the Principal Assay Scientist, you will play a key role in developing, validating, and scaling our Giant Magnetoresistance (GMR) biosensor platform. This position is ideal for a hands-on scientist who enjoys laboratory experimentation, problem-solving, and translating biological assays into robust sensor-based diagnostic solutions.

You will contribute to the development of multi-modal assay workflows for protein, DNA, and RNA detection while helping establish the laboratory capabilities and processes needed to support future product development and customer applications.

What You Will Do

Assay Development & Optimization

• Execute and optimize biosensor assays across a variety of biological targets and sample matrices, including blood, serum, and saliva.
• Support development of protein, nucleic acid, and multiplexed assay formats for GMR sensing applications.
• Conduct experimental studies to improve assay performance, sensitivity, robustness, and reproducibility.

Surface Chemistry & Process Development

• Perform surface functionalization, bioconjugation, and immobilization processes on sensor substrates.
• Support the development, characterization, and optimization of surface chemistry workflows for biosensor manufacturing and scale-up.
• Contribute to process improvement initiatives aimed at increasing assay consistency and performance.

Data Analysis & Technical Innovation

• Analyze experimental results using tools such as Excel, JMP, Python, or equivalent platforms.
• Identify technical trends, troubleshoot assay challenges, and communicate findings clearly to project stakeholders.
• Collaborate with scientists and engineers to develop innovative solutions for improving sensor performance and assay sensitivity.

Laboratory Operations

• Prepare reagents, buffers, controls, and test samples to support R&D activities.
• Maintain laboratory inventory, equipment calibration, documentation, and standard operating procedures.
• Ensure laboratory activities comply with safety and quality requirements.

Customer Applications & Product Support

• Assist in developing proof-of-concept demonstrations and customer-specific validation studies.
• Generate technical data and reports supporting customer evaluations, product verification, and manufacturing transfer activities.
• Support high-priority customer testing and application development efforts.

Cross-Functional Collaboration

• Partner with electrical, mechanical, software, and manufacturing engineers to integrate biological assay requirements into system design.
• Provide biological and assay-development expertise during product development, verification, and troubleshooting activities.

What You Will Bring

• B.S. or M.S. in Biochemistry, Molecular Biology, Bioengineering, Chemistry, or a related discipline.
• 3-6 years of hands-on laboratory experience in biotechnology, diagnostics, medical devices, or related R&D environments.
• Experience with standard laboratory techniques, including pipetting, solution preparation, dilution series, ELISA, or molecular biology workflows.
• Experience with surface chemistry, bioconjugation, or immobilization of biological capture reagents.
• Strong experimental design, troubleshooting, and data analysis skills.
• Proficiency in Excel and statistical analysis tools; experience with JMP, Python, or equivalent software is highly desirable.
• Excellent organizational skills and attention to detail.

Preferred Qualifications

• Experience working with biosensors, diagnostics, immunoassays, or molecular detection technologies.
• Familiarity with process development, manufacturing transfer, or semi-automated laboratory workflows.
• Experience working in highly multidisciplinary product development environments.
• Exposure to regulated product development or quality systems is a plus.

Why Allegro?

Join Allegro and become part of a team where your contributions truly matter. We foster a culture of Real Innovation , empowering you to push boundaries, develop cutting-edge solutions, and drive continuous improvement. Your work will create a Real Impact by solving complex real-world challenges that fuel our success and shape the future of technology. You'll experience Real Connection , collaborating with talented colleagues around the globe in an environment built on trust, respect, and a shared purpo