Senior Research Associate (Bioengineering)

ODDITY LABS; Cambridge (MA); On-site; USD 110,000 - 160,000; Full time

Benefits offered by this job

Visa sponsorship

In-office Cambridge location

Job summary

ODDITY LABS is seeking a Senior Research Associate to serve as the hands-on technical anchor for dermatology assay workflows in our Cambridge, MA laboratory. You will execute, optimize, and document experiments that support target validation and translational substantiation, working closely with PhD scientists and training junior staff.

You will manage cell-based, biochemical, and ex vivo assays, ensure assay reliability, and contribute to data generation and SOP improvements.

Qualifications

• Bachelor's degree in biological sciences or related field; Master's preferred.
• 4–5 years of hands-on lab experience in cell/molecular biology.
• Proficiency in multiplex immunoassays, qPCR, and cell-based screening.
• Experience with reporter cell lines, flow cytometry, ELISA, and cytokine profiling.
• Strong documentation discipline and reproducible record-keeping.

Responsibilities

• Execute and troubleshoot cell-based, biochemical, and phenotypic assays including ELISA, MSD, HTRF/TR-FRET, qPCR, reporter gene assays, viability assays, and flow cytometry.
• Support ex vivo tissue studies and IVPT/Franz diffusion experiments, coordinating with partners and handling samples.
• Maintain cell lines, reagents, and inventory; ensure QC and traceability of experiments.
• Optimize protocols for throughput, reproducibility, and cost efficiency.
• Draft and maintain SOPs and ELN entries for internal review and partner handoffs.

Skills

Multiplex immunoassays

qPCR

Cell-based screening

Flow cytometry

Biochemical assays

Fluorescence imaging

Mammalian cell culture

Genetic manipulation

Protein quantification

Histology

Education

Bachelor's degree in biological sciences, bioengineering, chemistry, or related field

Master's degree preferred

Tools

LC/MS

Job description

ODDITY is a consumer tech company that builds and scales digital-first brands to disrupt the offline-dominated beauty and wellness industries. The company serves over 40 million users with its AI-driven online platform, deploying data science to identify consumer needs, and developing solutions in the form of beauty and wellness products. ODDITY owns IL MAKIAGE, SpoiledChild, and medical-grade skincare and telehealth platform METHODIQ. ODDITY LABS is our cutting-edge biotechnology R&D center, powering science-backed product innovation through the discovery and development of new molecules, probiotics, peptides, and other biological modalities. Unlike pharmaceuticals, ingredient innovation in the beauty and wellness industry has remained stagnant for decades. We are deploying patented, proprietary technologies and capabilities, including AI-based molecule discovery and advanced phenotypic databases, to understand the biological mechanisms that drive cellular behavior and develop uniquely efficacious products for beauty and wellness applications. Innovations from the ODDITY LABS will power game-changing products through ODDITY’s current brands, as well as future brands.

ODDITY operates with business headquarters in New York City, an R&D center in Tel Aviv, Israel, and a biotechnology lab in Boston. Our culture is fast-paced, innovative, agile, and offers every team member the opportunity to drive a big impact.

THE ROLE

We are seeking a Senior Research Associate to be the hands-on technical anchor for dermatology assay workflows — executing, optimizing, and documenting experiments that support target validation, screening, and translational substantiation. You will work closely with PhD scientists, owning day-to-day bench execution while contributing protocol improvements and training junior staff. This is a high-skill, high-autonomy RA role. Success is measured by reproducible data, assay reliability, and the quality of experimental support you provide to discovery teams.. In this role, you will:

• Execute and troubleshoot cell-based, biochemical, and phenotypic assays: ELISA, MSD, HTRF/TR-FRET, qPCR, reporter gene assays, viability/cytotoxicity, and flow cytometry.
• Run in vitro safety packages including genotoxicity, phototoxicity, sensitization, and irritation screens under established SOPs.
• Support ex vivo human skin explant studies: tissue handling, sample preparation, endpoint readouts, and coordination with analytical partners.
• Assist with IVPT / Franz diffusion experiments: chamber setup, sampling, permeation sample handling, and LC/MS handoff logistics.
• Maintain cell lines, reagents, and lab inventory; ensure experiments meet QC and traceability standards.
• Optimize existing protocols for throughput, reproducibility, and cost efficiency.
• Draft and maintain SOPs, ELN entries, and raw data packages suitable for internal review and external partner handoff.
• Perform basic data analysis and figure preparation for scientist-led program updates.
• Flag experimental anomalies, propose troubleshooting paths, and document deviations.
• Support an environment that enables a staff of highly skilled and specialized peers to perform biological and computational experiments and promote trust and decision-making.
• Contribute to promoting a unified office/laboratory culture by organizing and assisting in planning community-building activities.
• Ensure a clean and safe environment for all laboratory personnel. Enforce and support universal precautions and use of personal protective equipment for all laboratory personnel.

WHO YOU ARE

• Bachelor's degree in biological sciences, bioengineering, chemistry, or related field (Master's preferred).
• 4–5 years of hands-on industry or academic laboratory experience in cell/molecular biology.
• Demonstrated proficiency in multiplex immunoassays, qPCR, and cell-based screening — not solely maintenance-level techniques.
• Proven expertise with functional assays including reporter cell lines, flow-cytometry, ELISA, cytokine profiling, biochemical assays, and fluorescence imaging.Experience with documentation discipline: ELNs, lab notebooks, SOP adherence, and reproducible experimental records.
• Ability to work independently on assigned protocols while collaborating in a fast-paced, matrixed R&D environment.
• Strong organizational skills and attention to detail under concurrent experiment timelines.
• You have extensive experience with mammalian cell culture, particularly experience with handling primary human cells and immortalized cell lines. Experience with stem cells, iPSC differentiation, various culture substrates, and/or 3D models is ideal.
• You have prior experience with genetic manipulation of mammalian cells (using either viral vectors, RNAi, CRISPR, etc) and molecular biology techniques, such as nucleic acid preparation, primer design, cloning and Western Blot.
• Previous experience in processing ex vivo tissue, including histology, transcriptomic profiling, and protein quantification is a plus.
• You have excellent written and verbal communication skills with experience working with a diverse range of stakeholders.
• You have a strong attention to detail and are committed to maintaining ODDITY LABS’ high standards and scientific rigor.
• You are willing to learn new skills as needed to help the team be as successful as it can be.
• You are an independent problem solver, consistently thinking out of the box and taking the initiative to take the next step without instruction.
• You are a hard worker with a high level of accountability. You hold yourself to high standards but also expect those around you to as well.

WHAT WE OFFER

• Competitive compensation and benefits package.
• This position will consider and sponsor candidates on a visa (OPT, STEM OPT, H1B, TN).
• This position is in-office in our Cambridge, Massachusetts office and laboratory.
• The salary for this position is negotiable and commensurate with experience.

Note: We’re currently hiring for many roles! Not the right fit, but interested in another position? Contact us [e-mail]