Senior Research Associate, Bioanalytical

Sci.bio Recruiting; Boston (MA); On-site; USD 70,000 - 95,000; Full time

Job summary

Sci.bio Recruiting is seeking a Research Associate or Senior Research Associate in Bioanalytical Sciences to support discovery, pharmacology, and preclinical programs. The role emphasizes hands-on MSD-based immunoassay development and troubleshooting in a busy biotech setting.

The successful candidate will perform ELISA assays, sample prep, data analysis, and cross-functional communication, with opportunities for growth in a collaborative environment.

Qualifications

• BS + 3 years or MS + 1 year of hands-on laboratory experience in biotech, pharma, CRO, or related setting.
• Degree in biochemistry, molecular biology, immunology, bioengineering, or related discipline.
• Hands-on experience with MSD ELISA assays is required.
• Working knowledge of ligand-binding assays, including assay design, reagent selection, matrix effects, and standard curve analysis.
• Experience with cell culture, transfection, iPSCs, or primary cell culture is a plus.
• Proficiency with GraphPad Prism and Excel and comfort applying basic statistics to quantitative assay data.
• Experience with an ELN/LIMS such as Benchling and strong documentation practices.
• Strong communication skills with the ability to work independently, manage multiple studies, and meet timelines with minimal supervision.

Responsibilities

• Execute MSD ELISA immunoassays supporting pharmacokinetic, biodistribution, target engagement, and biomarker studies.
• Develop, optimize, and qualify MSD methods, including reagent selection, titration, matrix/interference assessment, spike recovery, parallelism, dilutional linearity, precision, assay range, and analyte stability.
• Prepare biological samples for quantitative analysis, including tissue homogenization and cell lysate preparation.
• Analyze, interpret, and present bioanalytical data to cross-functional discovery teams.
• Maintain accurate laboratory records and ensure adherence to protocols and applicable requirements.
• Support laboratory operations, reagent inventory, and assay transfers to external CRO partners as needed.

Skills

MSD ELISA assays

GraphPad Prism

Excel

Benchling

Statistics

Education

BS in Biochemistry / Molecular Biology / Immunology / Bioengineering or related

MS in related field with 1 year experience

Tools

Benchling

Job description

Contract Research Associate / Senior Research Associate, Bioanalytical Sciences

Position Overview

We are seeking a Research Associate or Senior Research Associate, Bioanalytical Sciences to support discovery, pharmacology, and preclinical development programs. This is a hands-on, bench-focused role centered on the execution, troubleshooting, optimization, and development of quantitative bioanalytical assays, with a strong emphasis on MSD-based immunoassays.

Key Responsibilities

• Execute MSD ELISA immunoassays supporting pharmacokinetic, biodistribution, target engagement, and biomarker studies.
• Develop, optimize, and qualify MSD methods, including reagent selection, titration, matrix/interference assessment, spike recovery, parallelism, dilutional linearity, precision, assay range, and analyte stability.
• Prepare biological samples for quantitative analysis, including tissue homogenization and cell lysate preparation.
• Analyze, interpret, and present bioanalytical data to cross-functional discovery teams.
• Maintain accurate laboratory records and ensure adherence to protocols and applicable requirements.
• Support laboratory operations, reagent inventory, and assay transfers to external CRO partners as needed.

Qualifications

• BS + 3 years or MS + 1 year of hands-on laboratory experience in biotech, pharma, CRO, or a related setting.
• Degree in biochemistry, molecular biology, immunology, bioengineering, or a related discipline.
• Hands-on experience with MSD ELISA assays is required.
• Working knowledge of ligand-binding assays, including assay design, reagent selection, matrix effects, and standard curve analysis.
• Experience with cell culture, transfection, iPSCs, or primary cell culture is a plus.
• Proficiency with GraphPad Prism and Excel and comfort applying basic statistics to quantitative assay data.
• Experience with an ELN/LIMS such as Benchling and strong documentation practices.
• Strong communication skills with the ability to work independently, manage multiple studies, and meet timelines with minimal supervision.

What We Offer

An opportunity to work in a highly collaborative biotech environment supporting innovative therapeutic programs, with competitive compensation, benefits, and opportunities for professional growth.