Senior Programmer

ICON Clinical Research; United States; Remote; USD 90,000 - 130,000; Full time

Benefits offered by this job

Health insurance

Retirement planning

LifeWorks EAP

Life assurance

Flexible country-specific benefits

Job summary

ICON Strategic Solutions is seeking a Senior Statistical Programmer II to deliver statistical programming across multiple studies. The role focuses on SAS and R programming, ADaM datasets, and regulatory submissions, with mentorship for junior staff.

You will work independently on complex tasks, lead programming efforts for studies, and collaborate with cross-functional teams to ensure high-quality outputs. This remote role spans international therapeutic programs and study phases.

Qualifications

• Bachelor's degree in Statistics, Mathematics, Computer Science, Life Sciences, or a related discipline.
• 3+ years of statistical programming experience within the pharmaceutical, biotech, or CRO industry.
• Strong experience programming ADaM datasets and generating Tables, Listings and Figures (TLFs).
• Practical experience using SAS within clinical trials.
• Experience using R within a clinical research environment.
• Understanding of CDISC standards, including ADaM and SDTM.
• Experience supporting regulatory submissions and clinical study reporting.
• Strong problem-solving skills with the ability to work independently.
• Excellent written and verbal communication skills.

Responsibilities

• Develop, validate, and maintain complex SAS and R programs for clinical trial analysis and reporting.
• Lead statistical programming activities for assigned studies, ensuring high-quality and timely delivery.
• Create and review ADaM datasets, TLFs, and associated programming specifications.
• Collaborate with statisticians, data managers, and cross-functional study teams to deliver regulatory-compliant outputs.
• Support submission activities including Define.xml and other regulatory deliverables.
• Ensure programming deliverables comply with CDISC standards, ICH-GCP guidelines, and sponsor requirements.
• Perform quality reviews and contribute to programming standards and process improvements.
• Provide technical guidance and mentorship to junior programmers.
• Contribute to study-level planning, issue resolution, and continuous improvement initiatives.

Skills

Statistical programming

ADaM datasets

Tables, Listings & Figures (TLFs)

Independent work

Communication skills

Education

Bachelor's degree in Statistics/Mathematics/CS/Life Sciences

Tools

SAS

R

CDISC ADaM/SDTM

Define.xml

Job description

Senior Programmer - South Africa/Kenya/Poland/Hungary - Remote

At ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON's global expertise.

As the world's largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.

At ICON, it's our people that set us apart. As a global leader in clinical research, we partner with some of the world's most innovative pharmaceutical companies to accelerate the development of life-changing treatments.

We're currently expanding our dedicated Biometrics Partnership with one of our key clients and are seeking experienced Senior Statistical Programmers to join our growing team. This is an opportunity to work on high-profile clinical development programmes while collaborating with industry-leading experts in statistics, programming, and data sciences.

The Opportunity

As a Senior Statistical Programmer II, you will play a key role in the delivery of statistical programming activities across clinical studies, supporting analysis, reporting, and regulatory submissions. You'll work independently on complex programming tasks while contributing to study-level leadership and mentoring less experienced programmers.

This role offers exposure to a broad range of therapeutic areas and study phases, with opportunities across traditional clinical development, oncology, and real-world evidence programmes.

What You'll Be Doing

• Develop, validate, and maintain complex SAS and R programs for clinical trial analysis and reporting
• Lead statistical programming activities for assigned studies, ensuring high-quality and timely delivery
• Create and review ADaM datasets, Tables, Listings and Figures (TLFs), and associated programming specifications
• Collaborate with statisticians, data managers, and cross-functional study teams to deliver regulatory-compliant outputs
• Support submission activities including Define.xml and other regulatory deliverables
• Ensure programming deliverables comply with CDISC standards, ICH-GCP guidelines, and sponsor requirements
• Perform quality reviews and contribute to programming standards and process improvements
• Provide technical guidance and mentorship to junior programmers
• Contribute to study-level planning, issue resolution, and continuous improvement initiatives

What We're Looking For

Required Experience

• Bachelor's degree in Statistics, Mathematics, Computer Science, Life Sciences, or a related discipline
• 3+ years of statistical programming experience within the pharmaceutical, biotech, or CRO industry
• Strong experience programming ADaM datasets and generating Tables, Listings and Figures (TLFs)
• Practical experience using SAS within clinical trials
• Experience using R within a clinical research environment
• Understanding of CDISC standards, including ADaM and SDTM
• Experience supporting regulatory submissions and clinical study reporting
• Strong problem-solving skills with the ability to work independently
• Excellent written and verbal communication skills

Preferred Experience

• Experience acting as a lead programmer on studies or workstreams
• Oncology and/or Real World Evidence (RWE) experience
• Knowledge of Define.xml and submission package preparation
• Experience mentoring junior team members
• Previous experience working on GSK studies or within a sponsor-dedicated model

What ICON can offer you

• Various annual leave entitlements
• A range of health insurance offerings to suit you and your family's needs.
• Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
• Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family's well-being.
• Life assurance
• Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.

Our success depends on the quality of our people. That's why we've made it a priority to build a diverse culture that rewards high performance and nurtures talent.

In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.

At ICON, inclusion & belonging are fundamental to our culture and values. We're dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here

in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless - there's every chance you're exactly what we're looking for here at ICON whether it is for this or other roles.