Senior Product Manager / Staff Product Manager/ Principal Product Manager (Remote, US Only)

Genomenon, Inc; United States; Remote; USD 90,000 - 150,000; Full time

Job summary

An innovative AI-driven company is seeking a Senior Product Manager to lead the strategic planning and execution of cutting-edge genomic software solutions. This role is pivotal in shaping the product vision and guiding a high-performing team to deliver impactful solutions in rare disease diagnostics and drug development. Collaborating with cross-functional teams, you will ensure that our products meet market needs and enhance patient care. If you are a strategic thinker with a passion for healthcare technology and a desire to make a difference, this is your chance to join a mission-driven team dedicated to transforming genetic medicine.

Qualifications

• 5-10+ years of product management experience in a software or data-driven environment.
• Exceptional ability to translate between technical, operational, and business contexts.

Responsibilities

• Develop and oversee processes to improve product team efficiency.
• Conduct competitive and market analysis to inform product positioning.

Skills

Product Management

Agile Methodologies

Strategic Thinking

Communication Skills

Analytical Skills

Education

Bachelor’s degree in Life Sciences, Computer Science, Engineering, or Business

Advanced degree (MBA or PhD)

Tools

Jira

Confluence

Trello

Asana

Job description

Senior Product Manager / Staff Product Manager/ Principal Product Manager (Remote, US Only)

Remote, USA

Our Community

Genomenon team members are thoughtful, ambitious, and talented folks working together across multiple states and countries to improve the lives of our customers and patients.

We have genetic scientists, PhD’s, former clinicians, and talented professionals who are the best at what they do. Our team is mature and mission-driven, we work hard and collaborate as equals. We're looking for sharp people who want to contribute new perspectives to our community and help us curate the entire human genome. We value folks who are comfortable with rapid change and are excited to build a company together.

We are guided by our core values:

• Always Learning: Approach challenges with curiosity and a growth mindset
• Data-Driven: Ask a lot of questions and look to the evidence for answers
• Humbly Confident: Aware of the value that we and others bring to the team
• Customer & Patient Driven: Put patients and customers first in everything we do
• True Grit: Embody passion and persistence, and aren’t afraid of hard work

Our Company

Genomenon is an AI-driven, genomics software company. Our mission is to save and improve lives by making genomic information actionable. We organize the world’s genomic knowledge and put it at the fingertips of clinicians to help diagnose and treat patients suffering from rare diseases and cancer, and to help precision medicine companies create targeted therapies for diseases.

There are over 7,000 rare diseases affecting nearly 30 million Americans, 95% of which have no treatment. By harnessing AI and human insight, Genomenon's team is revolutionizing genetic medicine and leading a charge against genetic diseases and cancer for clinicians and pharmaceutical pioneers alike. And the adventure has just begun!

Join us in championing the spirit of Genomenon, where every data point is a beacon of hope, every insight a catalyst for change, and every person a vital thread in the fabric of progress.

/ge.gno.mai.non/
source language: ancient Greek
verb

• to come into being
• to be born out of need

noun

• the leader in Genomic Intelligence

At Genomenon, we are at the forefront of genomics research and innovation, with a mission to accelerate genetic discoveries and improve patient care.

We are looking for a proactive, driven Sales Development Representative (SDR) to identify and engage new business opportunities. This role involves working on an assigned territory to prospect new business, manage existing relationships, and support sales activities. The ideal candidate will have strong communication skills, experience in genetics, and the ability to collaborate effectively within a fast-paced sales environment.

The Opportunity

We’re seeking a senior-level Product Manager to organize the strategic planning, execution, and evolution of our AI-powered data solutions and software platforms used in rare disease and cancer diagnostics and drug development. You’ll collaborate across executive, engineering, science, data, and commercial teams to ensure our commercial solutions are impactful, scientifically sound, and aligned with market needs. Your work will help deliver meaningful value to clinicians, researchers, and pharma innovators worldwide and, most importantly, to the patients they serve.

This role offers the opportunity to help shape Genomenon’s product vision and play a key role in how we bring life-changing genomic insights to market. You’ll be responsible for guiding the activities of a small but high-performing product team, contributing to the definition of and execution against clear priorities for our engineering and AI teams, aligning stakeholders, and ensuring a seamless product development lifecycle from concept to launch. Your contribution will be instrumental in delivering innovative solutions that empower healthcare providers and precision medicine developers with the data they need to improve patient outcomes.

If you're a strategic thinker with strong product instincts, excited about building mission-driven technology in a dynamic, fast-paced environment, and motivated by the chance to impact real-world healthcare, we’d love to hear from you.

Position Responsibilities

• Product Operations
• Develop, implement, and oversee processes to improve product team efficiency and cross-functional collaboration.
• Establish, track, and analyze key performance indicators (KPIs) including financial performance, user engagement, and delivery metrics to guide product decisions.
• Prepare and deliver regular updates on product goals and progress to executive leadership, commercial teams, and the broader company through meetings, written reports, and internal newsletters.
• Oversee day-to-day product operations, optimizing workflows and delivery cadence across multiple teams.
• Product Management
• Conduct competitive and market analysis to inform positioning and identify opportunities for product differentiation. Support go-to-market strategies and messaging in collaboration with marketing and commercial teams.
• Capture evolving customer needs, market trends, and innovations in oncology diagnostics, genomics, AI, and healthcare to shape long-term product strategy.
  Own completion and refinement of product documentation, including roadmaps, requirements, user stories, and specifications.
• Lead sprint cadence, milestone tracking, and agile process facilitation in collaboration with technical product managers and engineering leads.
• Ensure proper user acceptance testing has been conducted for major and minor releases.
• Oversee day-to-day operations of product operations, optimizing workflows and delivery cadence.
• Portfolio and Strategy
• Support portfolio-wide product roadmap development, ensuring cohesion across product lines and alignment with company priorities.
• Contributing to customer discovery and market research initiatives.
• Contributing to portfolio-wide product roadmap development and presentation to all stakeholders including executive, commercial, development, and larger company.

About You

You are a mission-driven product professional and strategic, hands-on leader with a proven ability to earn trust and drive team performance in a fast-paced environment who thrives at the intersection of science, technology, and business. You know how to guide cross-functional teams, navigate technical complexity, and translate vision into clear, actionable plans. You bring clarity, energy, and accountability to every stage of the product lifecycle and you’re driven to help shape the future of precision medicine.

Skills and Background

• Proven leadership with the ability to earn trust and drive team performance
• Highly organized with strong project and time management skills
• Skilled communicator across executive, engineering, and peer teams
• Strategic thinker with strong analytical and problem-solving capabilities
• Results-oriented with a strong sense of ownership and accountability

Qualifications

Required

• Bachelor’s degree in a relevant field such as Life Sciences, Computer Science, Engineering, Business, or a related discipline
• 5-10+ years of product management or equivalent experience in a software or data-driven environment
  • Years of experience will help determine title, level, and compensation
• Exceptional ability to translate between technical, operational, and business contexts
• Experience with agile product development processes and tools (e.g., Jira, Confluence, Trello) and familiarity with project management platforms (e.g., Asana, Monday.com, Smartsheet, Microsoft Project) is preferred

Preferred

• Advanced degree in a life science, health IT, business, or technical field (e.g., MBA or PhD)
• Experience in healthcare, genomics, clinical diagnostics, pharma, or health IT sectors
• Familiarity with APIs, structured data, patient data, or genetic variant interpretation
• Training or certification in product (e.g., Pragmatic Institute, AIPMM, CSPO/PSPO) or project management (e.g., PMP, PMI-ACP, SAFe, Scrum Master) is a plus
• Experience working with AI/ML-enabled products or LLM-driven tools
• Knowledge of regulatory or clinical environments (e.g., HIPAA, FDA, CLIA)

Nice to Have

• Direct experience in clinical diagnostics, drug development, genomics, health IT, or artificial intelligence is a strong plus but not required. We value candidates with a strong learning mindset and the ability to ramp up quickly in complex domains.
• Familiarity with APIs, data structures, and genetic or clinical data is valuable, and can be developed through hands-on experience and team support.
• Familiarity with product management tools (e.g., Jira, Confluence, roadmap software) is preferred, but not required.

Our Commitment

The only way to build a great company is by hiring talented people with diverse backgrounds and rich life experiences. Those experiences contribute to our culture and help us find creative solutions to the tough problems we're solving. Because of this, we are committed to inclusion across race, gender, age, religion, identity, disability, and background in everything we do.

Historically, women and people of color are hesitant to apply for a role unless they meet every qualification listed in the job description. If you are uncertain if you're a fit, please apply. We'd rather have one more resume to review than miss the chance to meet amazing talent.

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