Senior Product Manager, Science

OpenKrill; United States; Remote; USD 144,000 - 205,000; Full time

Benefits offered by this job

Health insurance

Parental leave

401(k) with match

Well-being benefits

Flexible PTO

Remote work options

Home office stipend

Job summary

Helix is seeking a Senior Product Manager to lead clinical genomics workflow products, including case management, data workflows, clinical review and sign‑out, and data delivery. You will translate clinical inputs into a scalable roadmap for cross‑functional teams.

You will drive AI-enabled features, balance tradeoffs, and partner with lab directors, scientists and engineers to deliver high‑quality releases while upholding data privacy, governance and clinical quality.

Qualifications

• 5+ years of software product management in biotech or clinical setting.
• Experience with AI tools and implementing AI-driven automation.
• Strong ability to translate clinical needs into product requirements.
• Excellent cross-functional collaboration and communication.

Responsibilities

• Define product vision and roadmap for case management and data workflows.
• Work with lab directors, scientists, and engineers to deliver releases.
• Ensure data privacy and governance in AI-driven solutions.

Skills

PM experience

AI fluency

Clinical genomics knowledge

Communication

Execution mindset

Education

B.S. or M.S. in Biology/Engineering

Tools

SQL

Programming basics

Job description

Who We Are & What We Do

At Helix, our mission is simple: to help everyone improve their lives through their DNA.

Ready to make a real‑world impact with your skills? At Helix, we're transforming healthcare by making genomics a standard of care. We partner with health systems and life science companies to accelerate the integration of genomic data into clinical practice. Join us in building a future where healthcare is personalized, proactive, and powered by genomics.

What is special about this role?

At Helix, we’re focused on improving patient lives, and this role sits at the center of that work. The Product team builds tools that support clinical genomics workflows at Helix. In this role, you’ll shape products for case management, data workflows, clinical review and sign‑out, and data delivery. Your work will help lab directors, scientists and engineering teams deliver genomic insights efficiently while protecting clinical quality.

As a Senior Product Manager, you will:

• Define the Vision: Set and own product priorities for case management, data workflows, clinical review and sign‑out, and data delivery, translating input from clinical users and business partners into a roadmap the team can execute against.
• Accelerate Innovation: Use AI to build and iterate quickly, from user research to prototypes to specs, giving it clear context so outputs need minimal rework, while reserving your own judgment for strategy and stakeholder alignment.
• Simplify Complexity: Distill nuanced clinical needs into elegant, scalable product requirements while maintaining a relentless focus on priority.
• Balance & Scale: Navigate high‑stakes tradeoffs to deliver efficiency and scalability without ever compromising on clinical quality.
• Unify Teams: Act as the bridge between lab directors, scientists, and global engineering teams to ensure seamless product releases.
• Guardian of Trust: Oversee the health of your product area, including data privacy, security, and governance within our AI‑driven solutions.

About you:

• Educational Foundation: B.S. or M.S. in Biology, Engineering, or a related technical field.
• Domain Expertise: Deep experience or knowledge of clinical genomics and variant interpretation; you understand the science behind the software.
• Proven PM Track Record: 5+ years of software product management experience in a biotech laboratory, ideally within a clinical setting.
• AI Fluency: Comfortable building AI tools and applying critical judgment to what they output and when AI‑driven automation is worth building to drive efficiency, all while keeping product integrity, user needs, business goals, and privacy or regulatory requirements in mind.
• Clarity & Collaboration: Exceptional communication skills with a natural ability to translate complex technical/biological nuances into clear, actionable product needs.
• Execution Mindset: Highly organized and reliable. You thrive in ever‑changing environments and have the backbone to make high‑stakes, risk‑based tradeoff decisions.

Pluses:

• CLIA/CAP and/or medical device experience.
• Some familiarity with SQL and relational databases, some simple programming abilities with any language.

Expected Interview Process:

1) Recruiter Screen 2) Manager Screen/Tech Screen 3) Onsite 4) Offer

Expected Pay For This Role:

There are 3 distinct parts to your Helix offer: 1) Base Salary 2) Annual Bonus 3) Equity

• Expected Helix Base: $144,000 - $205,000
• Expected Helix Discretionary Annual Bonus: 10% of your annual salary
• Equity: We offer generous equity at Helix. If you receive a Helix offer your recruiter will book dedicated time with you to educate you on our equity model.

Aside from working alongside brilliant, dedicated, passionate, down‑to‑earth, curious, warm, and thoughtful people, we also provide great benefits:

• Comprehensive Health Insurance with Date of Hire eligibility- Above average employer paid premium coverage

• 12 weeks Helix Paid Parental Leave option- 401(k) with employer matching of up to 3% and 100% Vesting on the Date of Hire- Comprehensive Well‑Being Benefits- Flexible PTO- Remote options for many roles and a home office stipend

What To Expect During Your First 90 days:

• First 30 days: you'll spend time learning the Helix way, completing training and onboarding for your roles, and getting introduced to your team and relevant stakeholders. You'll also gain a deeper understanding of our customers, our products, the impact we make in the lives of our communities, and how to thrive at Helix through participation in Helix U.
• Day 30 - 60: you'll spend time contributing to projects, deeply familiarizing yourself with team and company processes, and developing a deeper understanding of Helix’s products, services and capabilities.
• Day 60 - 90: you'll build your OKRs with your manager, start to take ownership of projects and initiatives on your team, and begin to demonstrate your impact on the Helix mission.

To learn how Helix collects, uses, and protects your personal information during the recruitment process, please review our Privacy Notice.

Helix is proud to be an equal opportunity employer, and committed to providing employment opportunities regardless of race, religious creed, color, national origin, ancestry, physical disability, mental disability, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, pregnancy, childbirth and breastfeeding, age, sexual orientation, military or veteran status, or any other protected classification, in accordance with applicable federal, state, and local laws.

#LI-Remote

CompensationThe base pay range for this role is $144,000 – $205,000 per year.