Senior/Principal Scientist, DEL Small Molecule Discovery

Lila Sciences; Cambridge (MA); On-site; USD 148,000 - 208,000; Full time

Benefits offered by this job

Medical, dental, and vision coverage

Flexible time off

Paid parental leave

Commuter benefits

Company subsidized lunch program

Job summary

Lila Sciences in Cambridge, MA is looking for a Senior/Principal Scientist specializing in Small Molecule Therapeutics. This role focuses on leading hit identification through DNA-encoded libraries (DEL) and executing robust screening methodologies in collaboration with cross-functional teams.

The ideal candidate should have a PhD and 6–8 years of experience in drug discovery, emphasizing assay development and the validation of resulting compounds. Attractive compensation, including equity, is offered for this innovative position.

Qualifications

• 6–8 years of relevant drug discovery experience.
• Proven success in DEL screening campaigns.
• Strong working knowledge of diverse hit identification methods.

Responsibilities

• Lead DEL screening campaigns from design through validation.
• Develop biochemical and biophysical assays for hit characterization.
• Establish collaborations for high-quality protein supply.

Skills

DNA-encoded library (DEL) screening

Biochemical and biophysical assay development

Collaboration with protein science

Cross-functional teamwork

Automation and robotics in research

Education

PhD in Biology, Chemical Biology, Biochemistry, or a related field

MS/BS with 10+ years of industry experience

Tools

SPR

BLI

DSF

ITC

Job description

Lila Sciences in Cambridge, MA is looking for a Senior/Principal Scientist specializing in Small Molecule Therapeutics. This role focuses on leading hit identification through DNA-encoded libraries (DEL) and executing robust screening methodologies in collaboration with cross-functional teams.

The ideal candidate should have a PhD and 6–8 years of experience in drug discovery, emphasizing assay development and the validation of resulting compounds. Attractive compensation, including equity, is offered for this innovative position.