Senior Principal Research Scientist

AbbVie; Irvine (CA); On-site; USD 156,000 - 297,000; Full time

Job summary

AbbVie is seeking a Senior Principal Research Scientist to lead analytical development for peptide therapeutics in a vibrant and innovative environment. The ideal candidate will have extensive experience in analytical chemistry and demonstrate leadership in advancing drug development initiatives. In this role, you will contribute significantly to cross-functional project teams and mentor upcoming talent in the field, ensuring high-quality deliverables for clinical trials. This position offers a compelling compensation package reflective of your expertise in the biopharmaceutical sector.

Benefits

Comprehensive benefits package including medical, dental, and 401(k).

Short-term and long-term incentive programs.

Paid time off including vacations and holidays.

Qualifications

• 18+ years of related industry experience for Bachelor's.
• 16+ years for Master's, 10+ years for PhD.
• Strong analytical and regulatory knowledge.

Responsibilities

• Lead analytical teams for drug development and peptide characterization.
• Develop regulatory strategies and handle submissions.
• Mentor junior staff and foster a culture of knowledge sharing.

Skills

Analytical techniques

Scientific leadership

Interpersonal skills

Education

PhD in Analytical Chemistry

Masters in Analytical Chemistry

Bachelors in Analytical Chemistry

Job description

Join to apply for the Senior Principal Research Scientist role at AbbVie

Join to apply for the Senior Principal Research Scientist role at AbbVie

This range is provided by AbbVie. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range

$156,000.00/yr - $296,500.00/yr

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013, following separation from Abbott. AbbVie combines the focus and passion of a leading-edge biotech with the expertise and capabilities of a long-established pharmaceutical leader, to develop and market advanced therapies that address some of the world's most complex and serious diseases. AbbVie employs approximately 50,000 people worldwide and markets medicines in more than 170 countries. Analytical Research and Development is seeking a Director (oral) Peptides to conduct process research and formulation development of parenteral and oral macrocyclic peptides from pre-clinical through early clinical phases.

Key Responsibilities:

• The candidate will lead analytical teams associated with drug substance and drug product development and characterization of peptides and other modalities.
• Leverage prior experience leading analytical efforts focused on phase appropriate peptide drug substance and drug product development.
• Experience developing global regulatory strategies including authoring regulatory submissions, and responding to regulatory questions across global markets.
• Lead across functions within project teams to deliver robust control strategies for starting materials, intermediates, drug substances and drug products.
• Proactively drives innovation by leveraging external networks, industry insights, and prior experiences to identify emerging trends, foster strategic partnerships, and implement forward-thinking solutions.
• Responsible for fit-for purpose method development, testing procedures, justifying specifications, and implementation of analytical control strategies to help the advancement of candidate molecules.
• Proactively advise and share knowledge and expert opinions with subordinates, peers, and senior management.
• Mentor and develop scientific staff in troubleshooting strategic and experimental issues and foster a culture of knowledge sharing.
• The position involves multi-disciplinary collaborations across Discovery, Development, Manufacturing, and Regulatory to execute and deliver material and information for clinical trials and regulatory submissions.
• The candidate will identify and nurture ideas for continuous improvement activities and initiatives within the department.
• This role may include management of direct reports.
  
  

Qualifications

• Bachelors, Masters, or PhD in Analytical Chemistry with a minimum of 18+ (B.S.), 16+ (M.S.), or 10+ (Ph.D.) years of related industry experience (advanced degree in Analytical Chemistry preferred) Experience with analytical aspects of advancing peptide modalities.
• Proven scientific leadership; strong interpersonal and communication skills for facilitating collaborations and a demonstrated ability to represent analytical in cross-functional development teams.
• In depth experience with analytical techniques required for peptide characterization, such as HPLC, SEC, chiral, amino acid analysis, peptide content, impurity identification, peptide mapping etc.
• Demonstrated leadership of technical teams and effective cross-functional communication
• Demonstrated capability to solve critical scientific and business problems
• Demonstrated ability to implement and to grow the capabilities of an analytical organization and develop scientists into future leaders
• Demonstrated experience with global regulatory expectations and regulatory filings in the peptide space.
  
  

Key AbbVie Competencies:

Interacts well with diverse groups within function and maintain strong working relationships with internal and external collaborators to enable higher performance.

• Learns fast, grasps the "essence" and can change course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.
  
  

Level And Compensation Will Be Commensurate With Experience.

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.
• This job is eligible to participate in our long-term incentive programs
  
  

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Other

• Industries

  Pharmaceutical Manufacturing and Biotechnology Research

Referrals increase your chances of interviewing at AbbVie by 2x

Sign in to set job alerts for “Principal Research Scientist” roles.

Principal Scientist, Simulation and Modeling

Irvine, CA $121,000.00-$230,000.00 1 day ago

Sediment Engineer/Scientist - Mid-to-Senior Level

Long Beach, CA $95,000.00-$125,000.00 4 months ago

Principal Research Scientist I -( On-site Irvine, CA)

Irvine, CA $121,000.00-$230,000.00 1 week ago

Principal Research Scientist I -( On-site Irvine, CA)

Senior ML Scientist, Amazon Games AI Research

Irvine, CA $150,400.00-$260,000.00 1 week ago

Orange, CA $90,563.00-$149,427.00 6 days ago

We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.