Senior Potency Method Dev Scientist – Cell-Based Assays

Takeda Pharmaceutical Co.; Lexington (MA); On-site; USD 90,000 - 141,000; Full time

Job summary

Takeda in Lexington, MA seeks a Senior Research Associate for Potency Method Development. You will design and transfer cell-based and ligand-binding potency assays, ensuring robust methods for biologics programs.

This hands-on role involves collaboration with Process Development, QC/QA, and external partners to drive product characterization and regulatory readiness. You will work under the Head of Cell-Based Potency Assay Development, contributing to method qualification studies and technology

Qualifications

• MS in Biology, Biochemistry, or related field with 0–2 years of industry experience; or BS with 1–3 years of experience.
• Experience with aseptic techniques and mammalian cell culture.
• Ability to plan, execute, analyze, and communicate complex studies with limited supervision.
• Strong collaboration and communication across cross-functional teams.
• Hands-on experience with potency/functional assays (cell-based, ELISA, flow cytometry, SPR).
• Experience with laboratory calculations and instrument operation.

Responsibilities

• Design, develop, qualify, and transfer cell-based and ligand-binding potency assays.
• Evaluate assay performance and fitness for purpose through qualification studies.
• Collaborate with Process Development, QC, QA, Analytical Sciences, CTOs, and partners to advance goals.
• Troubleshoot complex analytical methods to improve reliability and reproducibility.
• Author and review development reports, transfer packages, SOPs, and validation/qualification docs.
• Communicate findings via presentations, publications, posters, and patent-related contributions.
• Maintain compliance with quality standards, safety, data integrity, and documentation practices.

Skills

Aseptic techniques

Mammalian cell culture

Lab operations

Independent planning

Cross-functional collaboration

Education

MS in Biology/Biochemistry or related field

BS in Biology/Biochemistry or related field

Tools

Hamilton Vantage

Job description

Takeda in Lexington, MA seeks a Senior Research Associate for Potency Method Development. You will design and transfer cell-based and ligand-binding potency assays, ensuring robust methods for biologics programs.

This hands-on role involves collaboration with Process Development, QC/QA, and external partners to drive product characterization and regulatory readiness. You will work under the Head of Cell-Based Potency Assay Development, contributing to method qualification studies and technology