Senior Pharmaceutical Development Scientist

Placements24; United States; Hybrid; USD 120,000 - 200,000; Full time

Benefits offered by this job

Medical aid

Pension fund

Performance-based incentives

Hybrid role

Job summary

Placements24 represents a distinguished pharmaceutical company seeking a Senior Pharmaceutical Development Scientist to join their team in Klerksdorp in a hybrid role, blending essential laboratory work with remote data analysis and report writing.

You will drive formulation development from concept to early-stage development, collaborating with chemists, analytical scientists, process engineers, and regulatory affairs to advance the pipeline.

Qualifications

• Ph.D. or Master’s degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related field.
• Minimum of 5 years hands-on experience in pharmaceutical formulation development.
• Proven expertise in developing dosage forms and understanding drug delivery principles.
• Proficiency with relevant analytical instrumentation and methods for characterization and quality control.
• Strong knowledge of cGMP, ICH guidelines, and regulatory requirements for drug development.
• Excellent problem-solving, critical thinking, and experimental design skills.

Responsibilities

• Design and execute pre-formulation experiments for solubility and stability.
• Develop and optimize dosage forms for NCEs and existing products.
• Characterize drug substance and excipient properties.
• Utilize analytical techniques to assess performance and stability.
• Prepare development reports and regulatory documentation.
• Collaborate with chemists, analytical scientists, process engineers, and regulatory specialists.
• Manage multiple projects and milestones.
• Contribute to scale-up from lab to pilot and manufacturing.

Skills

Problem-solving

Analytical skills

Experimental design

Communication skills

Education

PhD or Master’s in relevant field

Job description

About the Role

Our client, a distinguished pharmaceutical company at the forefront of drug innovation, is seeking an accomplished Senior Pharmaceutical Development Scientist to join their team in Klerksdorp. This hybrid role integrates essential laboratory and research activities with remote data analysis and report writing, offering a dynamic work environment. You will be instrumental in the formulation, development, and optimization of novel pharmaceutical dosage forms, ensuring product efficacy, safety, and stability. This position requires a strong scientific background, extensive experience in pre-formulation and formulation development, and a deep understanding of pharmaceutical manufacturing processes. The ideal candidate is a problem-solver with excellent analytical skills and a passion for bringing life-changing medicines to patients. You will contribute significantly to the company's pipeline, driving projects from concept to early-stage development.

Key Responsibilities

• Design and execute experiments for pre-formulation studies, including solubility, stability, and compatibility assessments.
• Develop and optimize various dosage forms (e.g., tablets, capsules, injectables, topicals) for new chemical entities (NCEs) and existing products.
• Characterize drug substance and excipient properties relevant to formulation development.
• Utilize analytical techniques (e.g., HPLC, dissolution testing, DSC, TGA) to assess product performance and stability.
• Prepare comprehensive development reports, summaries, and regulatory documentation.
• Troubleshoot formulation and process-related issues, proposing effective solutions.
• Collaborate closely with chemists, analytical scientists, process engineers, and regulatory affairs specialists.
• Conduct literature reviews and stay updated on scientific advancements in pharmaceutical formulation and delivery systems.
• Manage multiple projects concurrently, ensuring timely completion of milestones.
• Contribute to the scale-up of processes from laboratory to pilot and commercial manufacturing.

Requirements

• Ph.D. or Master's degree in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or a related field.
• Minimum of 5 years of hands-on experience in pharmaceutical formulation development.
• Proven expertise in developing various dosage forms and understanding drug delivery principles.
• Proficiency with relevant analytical instrumentation and methods for characterization and quality control.
• Strong understanding of cGMP, ICH guidelines, and regulatory requirements for drug development.
• Excellent problem-solving, critical thinking, and experimental design skills.
• Ability to work effectively in both laboratory and remote settings, managing project timelines.
• Strong written and verbal communication skills, with experience in preparing technical reports.
• Experience with excipient selection and compatibility studies.
• Ability to work collaboratively in a multidisciplinary team environment.

Benefits

• Our client offers a competitive salary package and comprehensive benefits, including medical aid, pension fund, and performance-based incentives.
• Opportunities for professional development, including attending scientific conferences and advanced training, are provided.
• This hybrid role supports a healthy work-life balance.
• Contribute to groundbreaking pharmaceutical research and development in Klerksdorp.
• Join a team of dedicated scientists driving innovation in medicine.