Senior Parenteral Formulation Scientist

Initial Therapeutics, Inc.; Indianapolis (IN); On-site; USD 152,000 - 244,000; Full time

Benefits offered by this job

Company bonus

Comprehensive benefits

In-office/lab attendance

Job summary

Lilly in Indianapolis is seeking a highly motivated Scientist to join the Bioproduct Research and Development group, focusing on parenteral formulations of large and small molecules and novel modalities. The organization emphasizes development of genetic medicines and advanced drug delivery platforms.

You will lead hands-on formulation studies, build scalable processes, and collaborate across disciplines to support clinical development and tech transfer to manufacturing, contributing to

Qualifications

• Earned Bachelors degree OR Master's degree in Pharmaceutics or Pharmaceutical Sciences, Biochemistry, Chemical Engineering or a related field
• 10+ years of pharmaceutical or biotech industry experience
• Prior experience developing processes and understanding basic principles and analytical techniques necessary to characterize large molecules or biological materials
• Knowledge and understanding of parenteral drug formulation development, parenteral manufacturing and aseptic technologies, and/or drug product process development
• Ability and desire to communicate and work cross-functionally within the team and with other teams on a consistent basis.

Responsibilities

• Represent Drug Product team in CM&C teams and support the formulation and process development of protein, peptide, oligonucleotides and other novel modalities in clinical development
• Hands‑on experimental activities in formulation group to support clinical development of parenteral drug products and other complex formulations
• Build process capabilities for lab scale, early phase clinical scale, and scale up technologies for parenteral drug product and other complex formulations
• Support tech transfer of process and formulation to clinical manufacturing sites.
• Work closely with synthetic chemistry, toxicology, ADME groups, analytical teams and device teams to develop the drug product that is stable and patient centric.
• May need to support monoclonal antibody, proteins and peptide programs in various stages of development.
• Provide technical support in the areas of formulation and drug delivery.
• Partner with key teams such as discovery, and drug product delivery and device to develop innovative solutions with a patient focus in an integrated fashion.
• Collaborate with Discovery teams on establishing systems for seamless handoff of assets from discovery to clinical development.
• Innovate or assess cutting edge formulation methodologies for complex or unstable bioproducts (peptides, proteins, fusion proteins and drug conjugates)
• Identify and spearhead research efforts on understanding new drug delivery technologies in the areas of targeted drug delivery and other novel drug delivery fields, and establish proof of concept for technologies for appropriate assets under development
• Establish and leverage strategic relationships with academia and start-ups to accelerate and access emerging innovation.
• Drive a strong innovation agenda for the team leading to publications, presentations and industry wide influence
• Ability to wear multiple functional hats so that input into various complementary parts of the project can be managed in a rapid and localized manner

Education

Bachelor's or Master's degree in Pharmaceutics or Pharmaceutical Sciences, Biochemistry, Chemical Engineering or related field

Job description

Lilly in Indianapolis is seeking a highly motivated Scientist to join the Bioproduct Research and Development group, focusing on parenteral formulations of large and small molecules and novel modalities. The organization emphasizes development of genetic medicines and advanced drug delivery platforms.

You will lead hands-on formulation studies, build scalable processes, and collaborate across disciplines to support clinical development and tech transfer to manufacturing, contributing to