Senior Orchestration Software Engineer- Workflow & Integration

AstraZeneca plc; New Haven (CT); On-site; USD 140,000 - 190,000; Full time

Job summary

AstraZeneca plc in the United States is seeking a senior software engineer to lead orchestration of lab automation workflows. You will design state models, events, and adapters, coordinate with data engineers, and deliver production-grade releases with observability.

This role blends software with science-facing responsibilities and requires experience with automation, sensors, and data products. You will work across interfaces, SDKs, and schedulers to support analytics, ML features, and

Qualifications

• PhD +0 years or MS +4 years or BS +8 years in CS/Engineering, plus 4+ years building software for lab automation.
• Proficiency in Python, C#, or Java and experience with event-driven patterns and state machines.
• Experience with interfaces, SDKs, message buses, schedulers, data services, and SQL.
• Collaboration with scientists/operators, mechatronics/controls, and data engineers; clear, user-focused documentation.

Responsibilities

• Own orchestration software components meeting reliability and usability targets.
• Audit-ready data trails for setpoints, states, recipe steps, and analytics.
• Produce release notes, onboarding kits, and documentation.
• Improve orchestration reliability with telemetry and corrective actions.
• Support operator UAT and day-2 enablement and commissioning.

Skills

Python

C#

Java

Event-driven patterns

State machines

Education

PhD/MS/BS with lab/automation experience

Tools

SDKs

Message buses

Schedulers

SQL

Data contracts

Schema design

Job description

This is what you will do:

Be a key member of the Advanced Robotics & Data Orchestration Team within Alexion’s Product Development & Clinical Supply organization.You will own the software layer that coordinates instruments and robots into push-button, reusable workflows. You will design state models, events, and integration modules; partner with data engineering experts to define schemas and event contracts; and deliver production-grade releases with observability and rollback. This role is software-leaning and science-facing: experiencewith pharmaceutical product development workflows, verification via vision/sensors, and data product thinking will help you translatescientistneeds into robust orchestration.Help us accelerate life-changing therapies to patients with rare and ultra-rare diseases.

• Translate scientist and operator requirements (throughput, usability, exception paths, reliability targets) into orchestration designs and software implementations.

• Implement run-control logic (state models/events), exception handling, recovery/rollback, and scheduling for automated work cells and instruments.

• Develop reusable drivers/adapters and interface modules aligned to documented contracts, coding standards, andversioning,reviewcode,and tests for quality.

• Integrate instruments/robots with schedulers and data services using interfaces and SDKs; partner with data engineering experts to define schemas and event models to support analytics and ML features.

• Apply configuration-as-code, CI/CD, automated testing, and secure development practices; ship documented releases and migration guides.

• Instrument workflows with telemetry/logs/alerts; define service level indicators andobjectivesfor orchestration software;participatein postmortems and reliability exercises.

• Produce onboarding artifacts (connectivity patterns, validation checklists, example configurations) and support operator UAT and day-2 enablement.

• Support commissioning, cutovers, andhypercarefor priority workflows; track reuse, commissioning time, error/rerun reduction, and uptime.

You will be responsible for:

• Orchestration software components that meet reliability and usability targets across instruments and work cells.

• Audit-ready data trails for setpoints, states, recipe steps, and analytical outputs; alignment to validation and security expectations.

• High-quality documentation, release notes, and onboarding kits that enable repeatable adoption.

• Continuous improvement of orchestration software reliability using telemetry and corrective actions.

You will need to have:

• Education/experience: PhD + 0 years, or MS + 4 years, or BS + 8 years in Computer Science, Engineering, or a related field (or equivalent experience)—including 4+years building software for lab or industrial automation or robotics, with hands on orchestration or controls integration.

• Proficiencyin one or more languagescommonin automation (for example, Python, C#, or Java) and experience with event-driven patterns and state machines.

• Experience with interfaces, SDKs, and message buses; integrating with schedulers and data services; familiarity with schema design, data contracts, and basic SQL.

• Collaboration with scientists/operators, mechatronics/controls, and data engineers; clear, user-focused documentation.

• The duties of this role may require periodic work in a laboratory or manufacturing environment. As is typical of such roles, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around hazardous materials; gown/degownPPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

We would prefer for you to have:

• Experience withbiologicsworkflows (cell culture, purification, analytics) and integrating with ELN/LIMS/SDMS systems.

• Hands-on work with robotics SDKs, verification via vision/sensors, barcode or RFID, or material-handling subsystems.

• Familiarity with observability tooling (metrics/logs/alerts), defining service levels, and structuredpostmortems.

In person working statement:

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspirelife‑changingmedicines.In‑personworking gives us the platform we need to connect, work at pace, and challengeperceptions.That iswhy we work, on average, a minimum of four days per week from the office. We balance this expectation while respecting individual flexibility. Join us in our unique and ambitious world.

Date Posted: 01-oct-2026

Closing Date: 07-oct-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.