Senior Oncology Safety & Risk Director (Hybrid)

GlaxoSmithKline; Durham (NC); Hybrid; USD 218,000 - 363,000; Full time

Benefits offered by this job

Annual bonus

Long-term incentive program

Health care

Retirement benefits

Paid holidays

Paid vacation

Parental and medical leave

Job summary

GSK is seeking a Senior Scientific Director to lead pharmacovigilance and risk management for oncology assets in clinical development. You will shape safety strategies, communicate risks, and collaborate across functions to ensure robust benefit-risk profiles for patients globally.

The role emphasizes cross-functional leadership, regulatory engagement, and strategic safety evaluation, with a hybrid US-based work model and opportunities to influence programs across the portfolio.

Qualifications

• Degree in a health or life sciences discipline.
• 5+ years experience in pharmacovigilance or drug safety.
• Experience with signal detection, safety surveillance and risk management.
• Knowledge of global pharmacovigilance requirements.
• Strong clinical or scientific judgement.

Responsibilities

• Lead pharmacovigilance activities and risk mitigation strategies for assigned oncology assets and clinical trials.
• Oversee the evaluation and interpretation of safety data, including signal detection and assessment.
• Develop strategic approaches for safety issue evaluation within clinical development programs.
• Contribute to safety components of global regulatory submissions (e.g., INDs, DSURs, IBs).
• Mentor and coach junior team members as applicable.
• Represent Safety Evaluation & Risk Management (SERM) on Clinical Matrix and Project Teams.

Skills

Pharmacovigilance

Risk management

Safety data analysis

Regulatory liaison

Cross-functional leadership

Education

Advanced degree (PharmD/MD/PhD) or equivalent

Job description

GSK is seeking a Senior Scientific Director to lead pharmacovigilance and risk management for oncology assets in clinical development. You will shape safety strategies, communicate risks, and collaborate across functions to ensure robust benefit-risk profiles for patients globally.

The role emphasizes cross-functional leadership, regulatory engagement, and strategic safety evaluation, with a hybrid US-based work model and opportunities to influence programs across the portfolio.