Senior Manager, Statistical Programming — Hybrid Clinical Analytics Lead

PTC Therapeutics, Inc; Philadelphia (Philadelphia County); Hybrid; USD 147,000 - 185,000; Full time

Job summary

PTC Therapeutics, Inc is seeking a Senior Manager, Statistical Programming to lead programming activities across clinical development programs. The role involves ensuring timely analyses per protocols and SAPs, either directly or through CRO oversight, and contributing to SOPs and system implementations.

The position requires a Master's degree in a quantitative field with ≥5 years in statistics or programming, strong SAS and R skills, and CDISC experience.

Qualifications

• Master's degree in a quantitative science and ≥5 years in statistics or statistical programming in pharma/CRO.
• Demonstrated SAS programming skills (Base SAS, SAS/Stat, SAS/Graph, SAS macros, ODS).
• Working knowledge of R.
• CDISC experience in clinical data analysis and reporting.
• Excellent verbal and written communication.
• Ability to work independently in a fast-paced, matrixed environment.
• Strong analytical and time-management skills.

Responsibilities

• Leads statistical programming activities for assigned clinical development studies and programs.
• Ensures timely statistical analyses per protocols and SAPs, via direct or CRO oversight.
• Represents Biostatistics in study team meetings and advises on statistical issues.
• Participates in CRO selection, evaluation, and oversight.
• Reviews CRFs, CRF annotations, SAPs, TLGs and TLG shells.
• Interacts with CROs and vendors to ensure accurate analyses and deliverables.
• Creates/reviews derived dataset specifications and analysis datasets.
• May develop SOPs and training guidelines related to statistical programming.

Skills

SAS programming

R

CDISC experience

statistical programming

communication skills

independent work

Education

Master's degree in statistics/biostatistics/computer science

Tools

SAS

R

CDISC

Job description

PTC Therapeutics, Inc is seeking a Senior Manager, Statistical Programming to lead programming activities across clinical development programs. The role involves ensuring timely analyses per protocols and SAPs, either directly or through CRO oversight, and contributing to SOPs and system implementations.

The position requires a Master's degree in a quantitative field with ≥5 years in statistics or programming, strong SAS and R skills, and CDISC experience.