Senior Manager, Manufacturing Operations

Oath; Vacaville (CA); Hybrid; USD 140,000 - 160,000; Full time

Benefits offered by this job

Health insurance

Paid time off

Stock options

Job summary

Oath, a leading microbial sciences company, seeks a Senior Manager of Manufacturing Operations in Vacaville, CA. The role oversees SOPs, specifications, batch records, and release processes, coordinating with production, QA, supply chain, regulatory, and external partners to ensure scalable, compliant manufacturing.

You will build systems and standards across internal and external manufacturing partners, drive change control, and report KPIs to improve yield, quality, and throughput.

Qualifications

• BS or MS in biotechnology, biochemical engineering, chemical engineering, microbiology, or related discipline.
• 7+ years in biotechnology/biomanufacturing or related setting.
• Experience with manufacturing documentation and controlled processes.
• Experience working with external manufacturers or CDMOs a plus.

Responsibilities

• Develop and maintain manufacturing SOPs, work instructions, specifications, and process documentation.
• Establish and maintain product and raw material specifications and associated documentation.
• Coordinate preparation and maintenance of SDSs, COAs, COCs, batch records, and release documentation.
• Support QC and batch release processes, ensuring required testing and documentation are completed prior to release.
• Drive manufacturing change control and process change management.
• Coordinate activities across manufacturing, quality, regulatory, supply chain, shipping, and planning.
• Support technology transfer and operational readiness with external manufacturing partners and CDMOs.
• Establish, track, and report manufacturing KPIs, including yield, success rate, quality, throughput, and operational performance.
• Identify operational gaps and implement systems and processes that improve manufacturing reliability and scalability.
• Audit Oath vendors for compliance with process and procedures

Skills

Biotech manufacturing

SOP development

Documentation control

Cross-functional collaboration

Vendor management

Education

BS/MS in biotechnology or related

Tools

Excel

Google Suite

Slack

Job description

Senior Manager, Manufacturing Operations

About Oath:

Oath is a leading microbial sciences company that utilizes natural soil biology to offer innovative solutions to some of the most critical challenges facing our planet - the climate crisis and the shift to sustainable agriculture. We imagine a world where these crises are not just alleviated, but reversed, replenishing Earth's microbiomes.

Our solution has moved beyond the lab and into real-world deployment, focused on improving farmer livelihoods with teams in Rwanda, Europe, the United States, and expanding. When you join Oath, you become part of a collaborative network that prioritizes high quality scientific work. You will be working alongside trained scientists, talented commercial teams, and a broad network of partners—an ecosystem designed to help you do your best work and grow your capabilities.

Position Summary:

The Senior Manager, Manufacturing Operations will help build and operationalize the systems, processes, and standards required to scale Oath’s manufacturing activities. This role will work internally across production, quality, supply chain, regulatory, and technical teams and externally with vendors to ensure our processes are well documented, controlled, and ready for reliable execution across internal and external manufacturing partners.

Key Responsibilities:

• Develop and maintain manufacturing SOPs, work instructions, specifications, and process documentation.
• Establish and maintain product and raw material specifications and associated documentation.
• Coordinate preparation and maintenance of SDSs, COAs, COCs, batch records, and release documentation.
• Support QC and batch release processes, ensuring required testing and documentation are completed prior to release.
• Drive manufacturing change control and process change management.
• Coordinate activities across manufacturing, quality, regulatory, supply chain, shipping, and planning.
• Support technology transfer and operational readiness with external manufacturing partners and CDMOs.
• Establish, track, and report manufacturing KPIs, including yield, success rate, quality, throughput, and operational performance.
• Identify operational gaps and implement systems and processes that improve manufacturing reliability and scalability.
• Audit Oath vendors for compliance with process and procedures

Qualifications:

• BS or MS in biotechnology, biochemical engineering, chemical engineering, microbiology, or a related discipline.
• 7+ years of experience in biotechnology, biomanufacturing, fermentation, or a related manufacturing environment.
• Strong experience with manufacturing documentation, SOPs, specifications, and controlled processes.
• Experience working across manufacturing, quality, supply chain, and technical organizations.
• Experience working with external manufacturers or CDMOs is a plus.
• Familiarity with GoogleSuite, Excel, Slack and similar tools is a plus

Location: Hybrid, with regular presence at Oath’s Vacaville, California site. Ability to travel 20% of the time (Europe & Africa).

Job Type: Full-time, exempt position in the United States. At this time, Oath, Inc. is not able to provide visa sponsorship or work authorization support.

Compensation: $140,000 - $160,000/year + equity

• Health insurance
• Paid time off
• Stock options