Senior Manager: Manufacturing – Material Handling

Amgen; Holly Springs (NC); On-site; USD 150,000 - 190,000; Full time

Benefits offered by this job

Total rewards plan

Career development

Job summary

Amgen is seeking a Senior Manager of Manufacturing – Material Handling to lead a 24/7 GMP material handling team at its new state-of-the-art facility in North Carolina. You will drive organizational design, staffing, training, and compliance to ensure safe, reliable operations and successful facility startup.

You will collaborate across Manufacturing, Quality, Engineering, Supply Chain, and Process Development to optimize material flow, inventory accuracy, and performance.

Qualifications

• Doctorate or Master’s with Manufacturing & Operations experience.
• Bachelor’s with extensive Manufacturing & Operations experience.
• 10+ years in Manufacturing & Operations plus 2+ years in a managerial role.

Responsibilities

• Develop and lead a high-performing Material Handling organization.
• Champion safety, quality, and compliance culture.
• Collaborate with cross-functional teams to ensure reliable operations.
• Oversee material flow, inventory control, and GMP material management.
• Lead readiness activities for facility startup and sustained manufacturing.

Skills

Leadership

Communication

Problem-solving

Team management

Education

Doctorate degree

Master’s degree

Bachelor’s degree

Associate's degree

High School diploma/GED

Tools

SAP

MES

Electronic batch records

Barcode/RFID

Job description

HOW MIGHT YOU DEFY IMAGINATION?

You’ve worked hard to become the professional you are today and are now ready to take the next step in your career. How will you put your skills, experience, and passion to work toward your goals? At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies, reaching over 10 million patients worldwide. Come do your best work alongside other innovative, driven professionals in this meaningful role.

Be part of Amgen's newest and most advanced drug substance manufacturing plant. The Amgen FleX Batch facility combines the latest in disposable technologies with traditional stainless-steel equipment to allow for maximum flexibility in operations. The FleX Batch facility not only features the best in-class drug substance manufacturing technologies with embedded industry 4.0 capabilities, but it also integrates sustainability innovations to reduce carbon and waste, as part of Amgen's plan to be a carbon-neutral company by 2027.

Senior Manager: Manufacturing – Material Handling

Live

What you will do

Let's do this. Let's change the world. As a Senior Manager of Manufacturing – Material Handling, you will provide leadership and guidance to the team responsible for 24/7 GMP material handling operations supporting manufacturing across the facility.

In this vital role as a member of the Manufacturing leadership team, the Senior Manager, Manufacturing – Material Handling, will collaborate cross-functionally to enable the manufacture of drug substance in a new state-of-the-art manufacturing facility. This role is responsible for leading and developing Material Handling Front-Line Managers who oversee teams supporting the receipt, staging, movement, storage, inventory control, and delivery of GMP materials between the warehouse and manufacturing operations. Additionally, you will be accountable for organizational design, hiring, development, and training compliance of the Material Handling organization to ensure safe, reliable, and uninterrupted manufacturing operations. The position will also provide leadership and oversight for operational readiness activities to ensure successful facility start-up and sustained commercial manufacturing performance.

Responsibilities

• Develop and retain a diverse, high-performing Material Handling organization in alignment with operational readiness schedules to support successful facility startup and commercial GMP operations.
• Foster a strong safety, quality, and compliance culture while championing continuous improvement across all Material Handling activities.
• Collaborate as one team with Manufacturing, Warehouse Operations, Quality, Engineering, Supply Chain, Process Development, Automation, and network partners to ensure reliable execution of manufacturing operations.
• Lead the execution and continuous improvement of end-to-end material flow processes, ensuring the right materials are available at the right location and time to support uninterrupted manufacturing.
• Oversee inventory accuracy, material reconciliation, cycle counting, and GMP inventory control processes while ensuring compliance with regulatory and internal quality requirements.
• Own the Manufacturing Material Transfer Equipment program, ensuring equipment lifecycle management, availability, qualification, maintenance coordination, and operational readiness.
• Partner with Supply Chain and Warehouse Operations to optimize material staging, replenishment strategies, and production scheduling while minimizing operational risk.
• Provide leadership in troubleshooting operational issues affecting material availability and establish robust escalation and 24/7 support processes.
• Lead investigations related to material handling deviations, inventory discrepancies, and material management events while driving effective root cause analysis and corrective actions.
• Develop and implement departmental strategies aligned with organizational objectives while driving Operational Excellence, Lean Manufacturing, and continuous improvement initiatives.
• Lead and support internal and regulatory inspections for areas of responsibility, including inspection readiness, response development, and sustainable compliance strategies.
• Deliver against organizational financial commitments while optimizing labor, inventory utilization, and operational efficiency.

Win

What We Expect Of You

We are all different, yet we all use our unique contributions to serve patients. The experienced professional we seek is a collaborative partner with these qualifications.

Basic Qualifications

Doctorate degree and 2 years of Manufacturing & Operations experience

Master’s degree and 6 years of Manufacturing & Operations experience

Bachelor’s degree and 8 years of Manufacturing & Operations experience

Associate's degree and 10 years of Manufacturing & Operations experience

High School diploma/GED and 12 years of Manufacturing & Operations experience

AND 2 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources

Preferred Qualifications

• Demonstrated managerial experience supporting GMP manufacturing operations in a biologics or pharmaceutical manufacturing environment.
• Experience leading GMP material handling, manufacturing logistics, inventory management, or warehouse operations supporting manufacturing.
• Demonstrated experience implementing Operational Excellence, Lean Manufacturing, and continuous improvement methodologies.
• Experience with electronic inventory management systems (SAP, MES, electronic batch records, barcode/RFID technologies, or equivalent).
• Working knowledge of GMP material management, inventory control, material traceability, and regulatory compliance requirements.
• Cross-functional experience partnering with Manufacturing, Supply Chain, Engineering, Quality, and Process Development organizations.
• Excellent communication, leadership, organizational, and problem-solving skills with the ability to influence across multiple organizations.
• Demonstrated ability to develop high-performing teams and foster an inclusive, accountable, and collaborative culture.

Thrive

What You Can Expect Of Us

• Vast opportunities to learn and move up and across our global organization
• Diverse and inclusive community of belonging, where teammates are empowered to bring ideas to the table and act
• Generous Total Rewards Plan comprising health, finance and wealth, work/life balance, and career benefits