Senior Manager, Logistics

Dyne Therapeutics; Waltham (MA); On-site; USD 140,000 - 170,000; Full time

Job summary

Dyne Therapeutics is seeking a Senior Manager to oversee end-to-end logistics for clinical and commercial supply in a fast-paced setting in Waltham, MA. You will manage cold chain movements between CMOs, warehouses, and distribution partners, coordinating with Supply Chain, Quality, Manufacturing, Finance, and Commercial teams.

This hands-on role emphasizes SOP development, process improvements, and readiness for product commercialization, with GMP/GDP compliance and strong collaboration across

Qualifications

• Bachelor’s degree in a relevant field; certifications a plus.
• 6+ years in supply chain/logistics within regulated industries.
• Experience with cold chain, international shipping, and GMP/GDP standards.

Responsibilities

• Oversee domestic and international cold chain shipments across CMOs, 3PLs, and warehouses.
• Lead logistics for network re-supplies with internal/external partners.
• Ensure compliant documentation, tracking, and import/export activities.

Skills

GMP/GDP knowledge

Cross-functional collaboration

Communication skills

Problem solving

Multi-stakeholder management

Education

Bachelor’s degree in Supply Chain Management/Logistics/Life Sciences

APICS/IATA/SCPro certification (plus)

Advanced degree (preferred)

Tools

Oracle

SAP

Job description

Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn, and Facebook.

Role Summary

The Senior Manager plays a critical role in managing end-to-end logistics operations for both clinical and commercial supply. The role will coordinate and oversee cold chain material movements between Contract Manufacturing Organizations (CMOs), warehouses, and distribution partners. The Senior Manager partners closely with Supply Chain, Quality, Manufacturing, Finance, Commercial, and external partners and stakeholders to ensure seamless logistics operations, supply continuity, compliant flow of materials, and readiness for product commercialization. This is a hands‑on operational role with strategic elements focusing on day‑to‑day warehouse and courier management, process improvements, the development and maintenance of Standard Operating Procedures (SOP), and readiness for product commercialization.

Primary Responsibilities

Logistics Operations

• Coordinate and oversee domestic and international cold chain shipments between CMOs, warehouses, third‑party logistics providers (3PL), and other supply chain nodes.
• Serve as the logistics lead for network re‑supplies, working closely with internal stakeholders (Supply Planning, Quality, Manufacturing) and external partners (couriers, CMOs, customs brokers, warehouses, 3PLs).
• Ensure timely and compliant execution of shipments, including documentation preparation and review, courier booking, shipment tracking, import/export activities, post‑shipment follow‑up and closure.
• Troubleshoot logistics issues and implement corrective actions as needed.
• Ensure all logistics activities are conducted in compliance with GMP, GDP, and international trade regulations and maintain accurate shipment documentation.

Commercial Launch Readiness

• Support the set up of the 3PL for commercial launches.
• Collaborate with cross‑functional teams to establish processes and capabilities to support ongoing and future commercial operations.
• Develop, implement, and maintain necessary SOPs and work instructions.
• Develop and maintain strong, collaborative relationships with internal teams and external stakeholders and partners.
• Monitor courier, warehouse, and 3PL performance and drive improvements.
• Act as logistics liaison in cross‑functional and partner meetings to ensure alignment and proactive communication.

Education and Skills Requirements

• Bachelor’s degree in Supply Chain Management, Logistics, Life Sciences, or a related field. Advanced degree or certification (e.g., APICS, IATA, SCPro) is a plus.
• Minimum of 6 years of experience in supply chain, logistics, or trade compliance within biotechnology, pharmaceuticals, healthcare, or another regulated industry.
• Strong operational experience managing material movements across CMOs, 3PLs, and warehouses within a global network.
• Experience supporting clinical and/or commercial supply chains, including launch activities and building distribution infrastructure.
• Working knowledge of GMP/GDP standards, cold chain logistics, and international shipping regulations.
• Solid knowledge of customs clearance processes and import/export regulations.
• Experience with logistics systems (e.g., Oracle, SAP) preferred.
• Strong communication and interpersonal skills.
• Highly collaborative and proactive problem solver with the ability to operate independently in a fast‑paced environment.
• High attention to detail and organizational skills.
• Ability to manage multiple priorities and stakeholders simultaneously.

Location: Waltham, MA (On‑site)

Pay Range: $140,000 - $170,000 USD

Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.