Senior Manager, IT Technical Security

Cytokinetics; South San Francisco (CA); On-site; USD 202,000 - 235,000; Full time

Job summary

Cytokinetics, a specialty cardiovascular biopharmaceutical company, seeks an experienced cybersecurity leader to oversee and operate enterprise security platforms at its South San Francisco headquarters. You will monitor security posture, drive vulnerability tracking, and coordinate incident response with IT and business partners.

The role emphasizes collaboration, strong communication, and a rigorous, risk-based approach to protect critical systems in a hybrid enterprise environment.

Qualifications

• 8+ years of IT/cybersecurity experience, incl. 5+ years implementing enterprise security platforms.
• Strong understanding of the NIST framework and supporting procedures and controls.
• Strong verbal and written communication to present complex information clearly.
• Must be highly collaborative and work with IT and business colleagues.
• Be highly organized and curious.

Responsibilities

• Monitor security posture across cloud and on‑premises environments, endpoints, and apps.
• Maintain a structured process for vulnerability data collection, analysis and tracking.
• Collaborate to prioritize risks and support informed remediation decisions.
• Review configurations of critical infrastructure and harden per current standards.
• Maintain a technical security scorecard and report to CISO/IT regularly.
• Own investigation and response to cybersecurity events, including containment and remediation.

Skills

IT/cybersecurity experience

NIST framework

Verbal communication

Collaboration

Organized and curious

Education

Bachelor's degree or equivalent

Job description

Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction.

Cytokinetics continues to mature its Cybersecurity Program including its policies, procedures, controls, guidelines, and technologies. This role is responsible for performing the day-to-day oversight, implementation, and operations of technical platforms that support the broader Cybersecurity Program.

This individual should have a firm understanding of key technologies and features (e.g., authentication and access management platforms, multi-factor authentication technologies, end-point detection and remediation tools, OS and application hardening, cloud computing infrastructures, vulnerability and patch management, etc.).

This role is located in Cytokinetics’ South San Francisco headquarters.

Responsibilities:

• Monitor the security posture of enterprise technology environments across cloud and on-premises infrastructure, endpoints, networks, identity platforms, and business applications.
• Maintain a structured process for aggregating, analyzing, and tracking vulnerability data to identify trends, prioritize risks, monitor remediation progress, and support informed decision-making.
• Collaborate with internal stakeholders and external partners to assess, prioritize, and remediate security issues using a risk-based approach that balances business needs, operational impact, and security requirements.
• Review critical infrastructure platform configurations (e.g., Exchange, SharePoint, Teams, Box, Azure, and AWS, Firewalls) and work with internal and external support teams to harden in accordance with current security requirements and standards.
• Maintain a technical security scorecard and report to CISO and IT on a periodic basis.
• Own and coordinate the investigation and response to cybersecurity events and incidents, including triage, containment, remediation, recovery, and follow-up.

Qualifications:

• 8+ years of relevant IT or cybersecurity experience, including 5+ years implementing and managing enterprise security platforms; a bachelor’s degree in a related field or equivalent practical experience is preferred.
• Must have firm understanding of NIST framework and supporting procedures and controls.
• Strong verbal and written communication including presentation of complex information to the broad company in an easy and consumable format.
• Must have strong collaboration skills.
• Must be highly organized and curious.
• Be a highly collaborative team member with other IT as well as business colleagues to drive down security risk balanced with appropriate risk acceptance and soft-touch education as necessary.

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Pay Range:

The expected salary range for this position based on the primary location of South San Francisco, CA is $201,600-$235,200. The base pay offered will take into account internal equity and may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Base salary is just one component of our competitive total compensation package, which includes equity in the form of stock options and/or restricted stock units, comprehensive health, dental, vision, life and disability insurance coverage, 401k retirement benefits with employer match, learning and wellness stipends, and paid time off. Note that benefits are subject to change and may vary based on jurisdiction of employment.

Our employees come from different backgrounds, and we celebrate those differences. We are looking for the best candidates for our open roles, but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team, we would love to hear from you.

Cytokinetics is an Equal Opportunity Employer