Senior Manager FP&A

Monte Rosa Therapeutics, Inc.; Boston (MA); On-site; USD 160,000 - 210,000; Full time

Job summary

Monte Rosa Therapeutics, Inc. in Boston seeks a Senior Manager, FP&A to own planning, forecasting and analytics across operating expenses.

You will partner with department leaders to translate strategic priorities into credible financial plans and play a key role in annual planning, quarterly reforecasts, monthly close and Board reporting. You will build driver-based models, support cash/runway forecasting and work on pricing, contracts, and capital planning with a strong emphasis on controls

Qualifications

• Bachelor's degree in Finance, Accounting, Economics or related field.
• 7–10+ years in FP&A, corporate finance or accounting.
• Ownership of multiple budget/forecast cycles with senior leaders.
• Advanced Excel and financial modeling skills.
• Strong accrual accounting and month-end close experience.
• Biotech/life sciences background with NetSuite and EPM familiarity.

Responsibilities

• Own annual operating plan, quarterly reforecasts, long-range plan.
• Build driver-based models for headcount, costs, spend and allocations.
• Prepare monthly/quarterly variance analysis and forward-looking commentary.
• Contribute to cash forecasting, burn/runway analysis, Board materials.
• Model CRO/CDMO contracts, collaborations, equipment, software, infra.
• Model headcount, compensation cycles, recruiting and payroll forecasts.
• Coordinate month-end close and expense accounting with policy alignment.
• Improve FP&A processes, templates, self-service reporting; SOX readiness.

Skills

Advanced Excel

Financial modeling

Budgeting & forecasting

Cross-functional collaboration

Education

Bachelor's degree in Finance/Accounting/Economics

Tools

NetSuite

Adaptive (EPM)

Job description

Overview

We are seeking a Senior Manager, FP&A to join our Boston-based Finance team. Reporting to the Director, FP&A, this individual will support and own planning, forecasting, and analytics across a significant portion of the Company's operating expense base, partnering directly with department leaders to translate strategic priorities into credible financial plans.

This is a broad, high-visibility role with exposure to both our scientific organization and our corporate functions. You will be a core contributor to the annual planning cycle, quarterly reforecasts, monthly close, cash and runway analysis, and Board-level reporting. The scope is intentionally wide — we are looking for someone who wants to understand how the whole company works, not just one slice of it.

Responsibilities

Operating plan and forecasting: Own the annual operating plan, quarterly reforecasts and long-range plan for assigned areas.

Driver-based modeling: Build and maintain driver-based models for headcount, personnel costs, external spend, consumables, capital and allocations.

Variance analysis and reporting: Prepare monthly and quarterly reporting packages with budget-versus-actual variance analysis. Include forward-looking commentary on the full-year outlook.

Cash and runway modeling: Contribute to cash forecasting, burn analysis and runway management. Support financing planning, Board materials, budget presentations and external operating expense guidance.

Contract and investment modeling: Build financial models and decision support for CRO/CDMO and vendor contracts, collaborations, capital equipment, software and facilities. Evaluate resource allocation trade-offs across programs, platforms and infrastructure.

Headcount and compensation modeling: Model headcount plans, compensation cycles, recruiting plans and payroll/benefits forecasts with People Experience & Operations.

Month-end close and expense accounting: Work with Accounting on accruals, reclasses and spend validation. Check that expense classification follows policy and external reporting requirements.

Systems, controls and process: Improve FP&A processes, reporting templates and self-service reporting in NetSuite and planning tools. Support internal controls, SOX-readiness and audit requests on budgeting and forecasting.

Qualifications

Education: Bachelor's degree in Finance, Accounting, Economics or a related quantitative field.

Experience: 7–10+ years of progressive FP&A, corporate finance or accounting experience.

Budget and forecast ownership: Demonstrated ownership of multiple full budget and forecast cycles for meaningful cost centers, including direct work with senior non-finance leaders.

Modeling: Advanced Excel and financial modeling skills, able to build a clean, auditable, flexible model from a blank sheet.

Accounting: Strong command of accrual accounting and the month-end close process.

Preferred biotech and systems background: Biotech, pharma or life sciences experience, ideally at a clinical-stage company, with exposure to R&D cost centers. Also hands-on NetSuite and an EPM/planning tool (e.g., Adaptive), plus familiarity with public company reporting (10-Q/10-K, SOX, Board reporting).