Senior Machine Learning Engineer

Circadia Health; El Segundo (CA); On-site; USD 150,000 - 240,000; Full time

Benefits offered by this job

Meaningful stock options

100% medical coverage

401(k)

Generous time off

Team events & culture

Job summary

Circadia Health in El Segundo, CA seeks a Senior Machine Learning Engineer to own end-to-end model development from data to deployment. You will design, train, and evaluate clinical prediction models using time-series vital signs and EHR context, define ground truth with clinical teams, and ensure robust evaluation and backtesting.

Role involves production-scale ML Ops, monitoring real-world performance, and contributing to regulatory submissions.

Qualifications

• 5+ years building ML models that reached production and informed decisions.
• Strong Python and modern DL frameworks; fluency in classical ML.
• Experience with time-series or sequential data.
• Evaluation practice covering calibration, class imbalance, and temporal leakage.
• Experience building evaluation, backtesting, or model regression infrastructure.
• Strong SQL and experience with production data.
• Ability to present model behavior to non-technical stakeholders.

Responsibilities

• Design, train, and evaluate clinical prediction models with time-series features.
• Define ground truth, build adjudication workflows, and manage targets.
• Build eval harnesses, backtesting, and regression suites for model versions.
• Assess sensitivity, specificity, lead time, and alert burden in deployment.
• Assess performance across facilities, settings, and demographics.
• Ship with ML Ops support and contribute to validation studies and submissions.

Skills

ML production

Python & DL

Time-series

Evaluation & leakage

Backtesting infra

SQL & production data

Stakeholder comms

Job description

About Circadia Health

Circadia Health is a growth-stage healthcare AI company on a mission to prevent avoidable hospitalizations and transform senior-care operations. Our Circadia Intelligence Platform combines:

• Contactless sensing that monitors respiration and motion with medical-grade accuracy
• Native predictive models that detect 85% of preventable adverse events several days in advance
• Enterprise integrations that operationalize predictions directly inside EHR, care-coordination, billing, and compliance workflows

Today, our technology touches 40,000+ post-acute patients daily across skilled-nursing, home-health, and home-care networks. We are backed by leading healthcare and AI investors and headquartered in El Segundo, CA.

Why this role exists

At most companies the ML engineer supports the product. Here the model is the product, and its accuracy is the ceiling on what the whole platform can deliver. What we sell is the judgment layer on top of a corpus most teams will never get access to: 70,000 years of continuous vital signs joined to clinical records from more than 400,000 unique patients. You will own the models built on it end to end: what they predict, how they are evaluated, where the threshold sits, and when they ship. Ground truth is retrospective chart review, so your labels are imperfect and you will need to know exactly how.

What you'll own

• Model development. Design, train, and evaluate clinical prediction models, with feature engineering across physiological time series and structured EHR context.
• Labels and ground truth. Define what you are actually predicting with clinical teams, build adjudication workflows, and understand the noise in your targets.
• Evaluation and testing infrastructure. Build the eval harnesses, backtesting, and regression suites that let us ship new model versions and new configurations with confidence, including how flagging behaves and whether explanations hold up.
• Clinical evaluation. Sensitivity, specificity, lead time, and alert burden as the care team experiences them. Threshold selection is a clinical decision as much as a statistical one.
• Robustness. Find where performance varies across facilities, settings, and demographics, and quantify it.
• Production and evidence. Ship with ML Ops support on serving and deployment, monitor real-world performance, and contribute to validation studies and regulatory submissions.

Required Qualifications

• 5+ years building ML models that reached production and were used for real decisions
• Strong Python and modern deep learning frameworks, plus fluency in classical ML
• Experience with time-series or sequential data
• Evaluation practice covering calibration, class imbalance, and temporal leakage
• Experience building evaluation, backtesting, or model regression infrastructure
• Strong SQL and experience with production data
• Experience presenting model behavior and limitations to non-technical stakeholders

Preferred

• Healthcare ML, clinical prediction, EHR data, physiological signals, or early-warning systems
• Model validation supporting regulatory submission, or subgroup analysis in a clinical setting
• First-author publications, significant open source, competition results, or a high-bar research or engineering background

$150,000 - $240,000 a year

As a full-time Senior Machine Learning Engineer, you will be employed by Circadia Health, Inc. The anticipated annual base salary range for this full-time position is $150,000 - $220,000. The base range is determined by role and level, and placement within the range will depend on a number of job-related factors, including but not limited to your skills, qualifications, experience, and location.

Annual salary is only one part of an employee's total compensation package at Circadia Health. We also offer:

• Meaningful employee stock options
• 100% company-paid medical, dental, and vision coverage
• 401(k)
• Competitive time off with pay policies including vacation, sick days, and company holidays
• Impact: your work will influence care decisions for tens of thousands of seniors every day.
• Culture: hard-working, mission-driven, and collaborative — with weekly and monthly social events like yoga, beach bonfires, and Wednesday/Friday team lunches.

Circadia Health is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, color, religion, sex (including pregnancy, sexual orientation, or gender identity), national origin, age, disability, genetic information, veteran status, or any other status protected by law.