Senior Scientist, Real-World Evidence and Outcomes

Circadia Health; El Segundo (CA); On-site; USD 165,000 - 205,000; Full time

Benefits offered by this job

Stock options

100% company‑paid medical, dental, and

401(k)

Generous paid time off

Team events and culture

Job summary

Circadia Health in El Segundo, CA is seeking a Senior Scientist for Real-World Evidence and Outcomes. You will own end-to-end studies, from framing questions to publishing findings, using Medicare claims, EHR, and platform data.

Strong emphasis on causal inference, ROI, and cost-avoidance analyses. The role requires 5+ years in real-world evidence or health economics, with proficiency in R/Python/SQL and a track record of peer-reviewed work.

Qualifications

• Real-world evidence, outcomes research, or health economics experience in a company, consultancy, payer, or provider setting.
• Ability to translate technical findings into clear narratives for executives, customers, and payers.
• Clear track record of peer-reviewed publication.

Responsibilities

• Design and govern studies of the deployed Circadia platform, defining questions, cohorts, endpoints.
• Analyze Medicare claims, EHR, platform, and customer data using causal inference methods.
• Publish manuscripts and manage peer review, abstracts, and white papers.
• Define ROI and cost-avoidance analyses and report to stakeholders.

Skills

R or Python

SQL

Observational study design

Scientific writing

Data analysis

Education

MSc or PhD in epidemiology, health services research, biostatistics, health economics, public health, or related field

Tools

R

Python

SQL

Job description

About Circadia Health

Circadia Health is a growth-stage healthcare AI company on a mission to prevent avoidable hospitalizations and transform senior-care operations. Our Circadia Intelligence Platform combines:

• Contactless sensing that monitors respiration and motion with medical-grade accuracy


• Native predictive models that detect 85% of preventable adverse events several days in advance


• Enterprise integrations that operationalize predictions directly inside EHR, care-
  \u2013coordination, billing, and compliance workflows

Today, our technology touches 40,000+ post-acute patients daily across skilled-
\u2013nursing, home-
\u2013health, and home-
\u2013care networks. We are backed by leading healthcare and AI investors and headquartered in El Segundo, CA.

The Role

You will design and run the studies that establish what Circadia's platform does for patients and for cost. That means owning studies end to end: framing the question, choosing the design and comparators, running the analysis, and publishing.

Metrics you will work on include hospital readmission rates, fall rates, time to clinical intervention, emergency department and inpatient utilization, length of stay, total cost of care, and clinician productivity, such as documentation time saved by our AI scribe and charting tools.

This is our first dedicated outcomes research hire, so the scope is wide. You will own both the clinical evidence and the health economics: the peer-
\u2013reviewed publications and the ROI and cost-
\u2013avoidance analyses that payers, health systems, and operators ask for. You will also set the standard for how Circadia makes and substantiates claims.

You will work with the Chief Scientist, the analytics team, and clinical teams at customer facilities. Our data comes from live operations, not research protocols. It is large, real, and messy. The job is to design the strongest study that data permits, ship it, and move to the next one.

What You’ll Own

Study design and governance

• Scope studies of the deployed platform: define the question, cohort, observation period, and endpoints from operational data


• Choose and defend designs where randomization is not available: retrospective observational, matched cohort, difference-
  \u2013in-
  \u2013differences, interrupted time series, index-
  \u2013event designs


• Build comparison groups, baselines, and risk-
  \u2013adjustment approaches that hold up under external scrutiny


• Write prespecified analysis plans and decide up front what a study will and will not claim


• Own IRB submission and human-
  \u2013subjects determination, and conflict-
  \u2013of-
  \u2013interest and AI-
  \u2013assistance disclosure


• Shape how future deployments collect data so they are publishable by design

Analysis

• Analyze Medicare claims, EHR, platform, and customer operational data


• Apply matching and causal inference methods: propensity score and Mahalanobis matching, coarsened exact matching, mixed-
  \u2013effects models for facility-
  \u2013clustered data


• Reason about confounding, selection bias, immortal time bias, and balance diagnostics, and argue why a cohort or comparator is defensible


• Translate how Circadia operates and bills into claims-
  \u2013detectable logic (NPIs, place of service, RPM/RTM CPT codes, type-
  \u2013of-
  \u2013bill logic, Part A/B interaction, dual eligibility, benefit exhaustion, MDS)


• Define how Circadia calculates and reports ROI and cost avoidance, and run subgroup analysis to identify where the platform delivers the strongest outcomes

Publication and dissemination

• Draft and publish manuscripts in journals such as JAMDA and JAMIA, and manage peer review and revision


• Produce conference abstracts, white papers, and commercial evidence from the same analysis, without letting claims drift between versions


• Set the guardrails on what Circadia can and cannot claim from its evidence


• Present findings to clinical, payer, and executive audiences, and support customer and partner conversations

What We’re Looking For

• Industry research experience is required. This role is not a fit for candidates whose experience is entirely academic


• MSc or PhD in epidemiology, health services research, biostatistics, health economics, public health, or a related quantitative field


• 5+ years producing real-
  \u2013world evidence, outcomes research, or health economics work in a company, consultancy, payer, or provider setting


• Experience with health economics and outcomes research: cost, utilization, ROI, or cost-
  \u2013avoidance analysis alongside clinical endpoints


• Ability to translate technical findings into clear narratives for executives, customers, and payers


• Track record of peer-
  \u2013reviewed publication, ideally in a clinical specialty or informatics journal


• Command of observational and quasi-
  \u2013experimental study design, and clear thinking about its limits


• Proficiency with R or Python and SQL, and comfort with large, messy healthcare datasets


• Clear scientific writing, and experience carrying a manuscript through peer review

Especially Valuable

• Experience with Medicare, Medicare Advantage, skilled nursing, or senior care populations


• Working knowledge of Medicare claims structure and CMS post-
  \u2013acute quality measures (SNFRM, PPR)


• Experience in remote patient monitoring, medical devices, or digital health


• Experience evaluating AI or machine learning models in a clinical workflow


• Experience measuring clinician workload, documentation burden, or workflow efficiency, including clinical informatics evaluation


• Experience in a startup


• Familiarity with IRB pathways and reporting standards such as SQUIRE 2.0


• Experience working with actuarial firms or third-
  \u2013party claims datasets


• Understanding of value-
  \u2013based care economics and healthcare reimbursement

Work Environment

Based in our El Segundo office, five days per week. Occasional travel to skilled nursing facilities, hospitals, and conferences in California and beyond.

Reasonable accommodations will be provided in accordance with applicable federal and California law.

$165,000 - $205,000 a year

As a full‑time Senior Scientist, Real‑World Evidence and Outcomes, you will be employed by Circadia Health, Inc. The anticipated annual base salary range for this full‑time position is $165,000 - $205,000. The base range is determined by role and level, and placement within the range will depend on a number of job‑related factors, including but not limited to your skills, qualifications, experience, and location.

Annual salary is only one part of an employee's total compensation package at Circadia Health. We also offer:

• Meaningful employee stock options


• 100% company‑paid medical, dental, and vision coverage


• 401(k)


• Competitive time off with pay policies including vacation, sick days, and company holidays


• Impact: your work will influence care decisions for tens of thousands of seniors every day.


• Culture: hard‑working, mission‑driven, and collaborative — with weekly and monthly social events like yoga, beach bonfires, and Wednesday/Friday team lunches.

Circadia Health is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. All employment decisions are based on business needs, job requirements, and individual qualifications, without regard to race, color, religion, sex (including pregnancy, sexual orientation, or gender identity), national origin, age, disability, genetic information, veteran status, or any other status protected by law.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.