Senior Life Sciences Construction Project Manager

Orchestra Life Sciences; Philadelphia (Philadelphia County); On-site; USD 150,000 - 230,000; Full time

Benefits offered by this job

Competitive compensation

Comprehensive benefits

Professional growth opportunities

Job summary

Orchestra Life Sciences is seeking a Construction Project Manager to lead full lifecycle delivery of complex life sciences construction projects in the Philadelphia area. You will oversee multi-disciplinary teams, manage client relationships, and drive projects from pre-construction through closeout with a high degree of autonomy.

The role requires 10+ years in construction PM, 5+ years in life sciences or TI projects, and proficiency in Primavera, MS Project, Procore, and Bluebeam.

Qualifications

• Bachelor's degree in Construction Management, Engineering, Architecture, or related field.
• 10+ years of construction project management experience, with a minimum of 5 years on life sciences, pharmaceutical, or technically complex TI projects.
• Demonstrated experience managing projects from $10M to $100M+.
• Proficiency in Oracle Primavera (P6 or Cloud), MS Project, Procore, and Bluebeam.
• Strong understanding of construction contracts (AIA, ConsensusDocs), subcontract administration, and change management.
• Experience coordinating with regulatory bodies and navigating permitting processes.

Responsibilities

• Lead all phases of project execution including pre-construction, procurement, construction, and closeout.
• Develop and maintain project schedules using Oracle Primavera and MS Project; identify and manage critical paths.
• Manage project budgets, cost reporting, and CAPEX forecasting with accuracy and consistency.
• Oversee subcontractor procurement, scope development, contract administration, and performance management.
• Coordinate with design teams, structural engineers, specialty consultants, and regulatory bodies including AHJ.
• Manage submittal and RFI processes through PM software; ensure timely responses and documentation.
• Lead OAC meetings, prepare minutes, and maintain clear project communication across stakeholders.
• Manage projects within occupied or regulated environments (GMP, BSL, cleanrooms).
• Coordinate tenant improvement work within core and shell constraints; landlord/tenant interface management.
• Understand fire suppression, HVAC, hazardous materials, and specialty systems in life sciences facilities.
• Support commissioning and validation activities as required by client programs.
• Serve as primary owner contact; mentor junior PMs and engineers.
• Collaborate on pursuit strategy, staffing, and project reporting.
• Identify and elevate project risks and changes in a timely manner.

Skills

Leadership

Communication

Contract management

Regulatory coordination

Time management

Education

Bachelor's degree in Construction Management/Engineering/Architecture

Tools

Primavera P6/Cloud

MS Project

Procore

Bluebeam

Job description

Orchestra Life Sciences is seeking a Construction Project Manager to lead full lifecycle delivery of complex life sciences construction projects in the Philadelphia area. You will oversee multi-disciplinary teams, manage client relationships, and drive projects from pre-construction through closeout with a high degree of autonomy.

The role requires 10+ years in construction PM, 5+ years in life sciences or TI projects, and proficiency in Primavera, MS Project, Procore, and Bluebeam.