Senior Laboratory Automation Scientist

Johnson & Johnson; Spring House (PA); On-site; USD 120,000 - 160,000; Full time

Job summary

Johnson & Johnson in Spring House, PA, is seeking a Senior Laboratory Automation Scientist to own automation readiness for integrated workcells in discovery and analytical workflows.

You will translate complex biological and biochemical workflows into executable automated sequences, lead design, integration, qualification, and lifecycle support, and ensure data provenance, user adoption, and robust method transfer across platforms.

Responsibilities

• Workcell Architecture and Scientific Design
• Designing and deploying integrated workcells combining liquid handlers, plate handling devices, washers, centrifuges, incubators, readers, storage systems, barcode readers, labelers, analytical instruments, and orchestration software.
• Defining method transfer strategy from manual to automated execution, including pipetting approach, tolerance assumptions, deck layout, consumable selection, reagent stability, timing constraints, controls, and acceptance criteria.
• Leading UAT design for nominal workflows, edge cases, sample exceptions, data handoffs, intervention paths, recovery cases, and user acceptance.
• Inter-Workcell Integration and Data Provenance
• Owning upstream and downstream handoff requirements for assigned workcells, including labware compatibility, sample format, timing constraints, temperature or sterility constraints, storage conditions, queue logic, and data handoff expectations.
• Defining sample, labware, consumable, reagent, waste, intermediate product, and run state requirements for assigned workcells.
• Partnering with IT, data science, AI, and laboratory informatics teams to define metadata, sample lineage, experimental provenance, data integrity checks, file transfer expectations, and model-ready outputs.
• Supporting integration control documentation between workflows, workcells, orchestration layers, ELN, LIMS, GDB, data platforms, analytical systems, and vendor software.
• Recovery, Governance, and Sustainment
• Designing recovery logic for failed runs, interrupted workflows, missing samples, failed transfers, sample rescue, plate quarantine, rerouting, pause/resume situations, and manual interventions.
• Leading troubleshooting and root cause analysis for complex issues spanning method performance, liquid handling, consumables, assay response, scheduling, sample tracking, metadata, data capture, and user behavior.
• Supporting vendor selection, Tier 1 and Tier 2 coordination, FAT, SAT, UAT, risk assessments, readiness reviews, hypercare planning, training, and lifecycle support.
• Driving continuous improvement based on run metrics, failure mode analysis

Job description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com .

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function: R&D Product Development

Job Sub Function: R&D Electrical/Mechatronic Engineering

Job Category: Scientific/Technology

All Job Posting Locations: Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Senior Laboratory Automation Scientist to be located in Spring House, PA.

Purpose:

The Senior Laboratory Automation Scientist owns scientific automation readiness for one or more integrated workcells. The role translates complex biological, biochemical, analytical, and screening workflows into executable automated sequences that preserve sample identity, scientific intent, data context, and downstream decision value.

The Senior Scientist will lead design, integration, qualification, optimization, and lifecycle support of integrated laboratory automation workcells for discovery and analytical workflows, with explicit responsibility for scientific operability, handoffs, method robustness, data provenance, exception recovery, user adoption and workflow readiness.

This role is complementary to the Senior Automation and Robotics Engineer. The scientist owns the workflow, method, sample logic, data context, and user adoption; the engineer owns the physical system, machine behavior, robot motion, safety, serviceability, and engineering acceptance.

You will be responsible for:

Workcell Architecture and Scientific Design

Leading translation of scientific workflows into process maps, sample flows, consumable flows, method logic, instrument sequences, metadata needs, analytical outputs, data handoffs, and scientific decision points.

Designing and deploying integrated workcells combining liquid handlers, plate handling devices, washers, centrifuges, incubators, readers, storage systems, barcode readers, labelers, analytical instruments, and orchestration software.

Defining method transfer strategy from manual to automated execution, including pipetting approach, tolerance assumptions, deck layout, consumable selection, reagent stability, timing constraints, controls, and acceptance criteria.

Leading UAT design for nominal workflows, edge cases, sample exceptions, data handoffs, intervention paths, recovery cases, and user acceptance.

Inter-Workcell Integration and Data Provenance

Owning upstream and downstream handoff requirements for assigned workcells, including labware compatibility, sample format, timing constraints, temperature or sterility constraints, storage conditions, queue logic, and data handoff expectations.

Defining sample, labware, consumable, reagent, waste, intermediate product, and run state requirements for assigned workcells.

Partnering with IT, data science, AI, and laboratory informatics teams to define metadata, sample lineage, experimental provenance, data integrity checks, file transfer expectations, and model-ready outputs.

Supporting integration control documentation between workflows, workcells, orchestration layers, ELN, LIMS, GDB, data platforms, analytical systems, and vendor software.

Recovery, Governance, and Sustainment

Designing recovery logic for failed runs, interrupted workflows, missing samples, failed transfers, sample rescue, plate quarantine, rerouting, pause/resume situations, and manual interventions.

Leading troubleshooting and root cause analysis for complex issues spanning method performance, liquid handling, consumables, assay response, scheduling, sample tracking, metadata, data capture, and user behavior.

Supporting vendor selection, Tier 1 and Tier 2 coordination, FAT, SAT, UAT, risk assessments, readiness reviews, hypercare planning, training, and lifecycle support.

Driving continuous improvement based on run metrics, failure mode analysis,