Senior IT Systems Engineer - Cloud, Identity & Security

Treeline Biosciences, Inc.; Northern (KY); Hybrid; USD 180,000 - 197,000; Full time

Job summary

Treeline Biosciences, Inc. is seeking an experienced Principal Information System Engineer to join the IT team in Watertown. You will lead complex initiatives, escalate issues, and work with MSPs across departments and countries to maintain and improve our enterprise IT stack.

The role administers Microsoft 365, Intune, Entra ID, Okta, MFA, and PowerShell automation. Requires 8–10+ years in IT ops and a BA/BS in IT/CS or equivalent; biotech startup experience is a plus.

Qualifications

• Bachelor's degree in IT/CS or equivalent experience.
• 8–10+ years in systems administration, endpoint management, identity, or IT ops.
• Broad IT experience across Windows, Mac, databases, storage, security, networking and clouds.
• Hands-on with M365, Entra ID CA policies, Okta, endpoint security, PowerShell.
• Strong troubleshooting, problem-solving, and analytical skills.
• Ownership-driven in issue resolution; no problem is too big or small.
• Organized, detail-oriented, and able to document clearly.
• Excellent written and verbal communication; ITSM and ticketing familiarity.
• Ability to collaborate with local/remote coworkers and vendors.
• Curious, creative, and focused on process improvement.
• Biotech startup experience; related certifications are a plus.

Responsibilities

• Serve as primary escalation point for IT, including hands-on end-user support.
• Provide hands-on leadership for complex technical initiatives.
• Act as secondary technical decision-maker for IT Operations.
• Administer and optimize cloud-based enterprise technologies (endpoint, identity, security).
• Manage modern workplace technologies and troubleshoot issues.
• Administer Microsoft 365, Intune, Entra ID environments and CA policies.
• Manage identity solutions including Okta and MFA.
• Develop PowerShell scripts to automate tasks.
• Collaborate with in-house engineers and MSPs across departments/countries.
• Maintain documentation, tickets, and knowledge base per ITSM.
• Design, implement, and continuously improve IT solutions with vendors.

Skills

Troubleshooting

Ownership mindset

Communication

Analytical thinking

Collaboration

Education

Bachelor's degree in IT / CS or related field

Tools

Microsoft 365

Microsoft Entra ID

Okta

PowerShell

Intune

MS Entra Conditional Access

Job description

Treeline Biosciences, Inc. is seeking an experienced Principal Information System Engineer to join the IT team in Watertown. You will lead complex initiatives, escalate issues, and work with MSPs across departments and countries to maintain and improve our enterprise IT stack.

The role administers Microsoft 365, Intune, Entra ID, Okta, MFA, and PowerShell automation. Requires 8–10+ years in IT ops and a BA/BS in IT/CS or equivalent; biotech startup experience is a plus.