Senior IT Systems Engineer

10x Genomics, Inc.; Pleasanton, Northern (CA, KY); Hybrid; USD 137,000 - 185,000; Full time

Job summary

10x Genomics is seeking a Linux system administrator to design, implement, and operate enterprise and HPC compute and storage across hybrid environments, enabling secure, scalable access to multi-petabyte genomic datasets.

You will manage on-prem and cloud resources, enforce data protection, perform automated patching, and lead post-incident reviews to prevent recurrence, while supporting a high-availability research infrastructure.

Qualifications

• 5+ years managing petabyte-scale enterprise or HPC storage.
• Strong knowledge of data replication and backup technologies.
• Experience with Debian, Ubuntu and Amazon Linux, and AWS (S3, EC2, EBS, VPC, IAM).
• Scripting in Bash or Python; IaC tools such as Ansible or Terraform.

Responsibilities

• Design, implement, operate and document enterprise and HPC compute and storage across hybrid environments.
• Architect and maintain storage and compute clusters with patching and performance tuning.
• Manage off-site/cloud backup, archive, and data replication solutions; ensure operational readiness of backup systems.
• Enforce data integrity, security compliance and automated monitoring across production storage and backup systems.
• Manage data lifecycle of corporate and research datasets; implement DLM policies.
• Participate in a shared on-call rotation to support production environment.
• Lead post-incident reviews to identify root causes and implement long-term fixes.

Skills

Petabyte-scale storage

Data replication

Backup technologies

Linux distributions

AWS

NFS/SMB file sharing

Bash/Python scripting

IaC/Configuration mgmt

Tools

VMware ESXi/vCenter

Proxmox VE

Job description

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world. We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

About The Role

Information technology is a vital and integral part of our success. At 10x Genomics, IT not only provides a secure, stable, and scalable infrastructure for R&D, manufacturing, and business operations, it serves as a catalyst for innovation and productivity. We are looking for an exceptional Linux system administrator with strong data protection experience to join our IT team. You will be working with a growing infrastructure that serves multi-petabytes of genomic data in a High Performance Computing environment while delivering optimal performance, availability, and durability.

What you will be doing

• Design, implement, operate and document enterprise and HPC compute and storage across hybrid (on-premises and cloud) environments.

• Architect and maintain storage and compute clusters in accordance with best practices for configuration management, automated patching, and performance tuning.

• Manage off-site/cloud backup, archive, and data replication solutions. Ensure operational readiness of all backup systems.

• Enforce data integrity, security compliance and automated monitoring across production storage and backup systems.

• Manage data lifecycle of corporate and research datasets. Implement and enforce DLM policies.

• Participate in a shared operational on-call rotation to support our production environment.

• Lead post-incident reviews to identify root causes and implement long-term preventative fixes.

Minimum Qualifications

• 5 years managing petabyte-scale enterprise or HPC storage, including scale-out NAS, with a focus on performance, data protection, and integrity.

• Strong knowledge of data replication and backup technologies.

• Strong knowledge of diverse Linux distributions including Debian, Ubuntu and Amazon Linux.

• Experience with AWS (S3, EBS, EC2, VPC, IAM).

• Solid knowledge of cross-platform file sharing protocols (NFS, SMB) and access control (Active Directory/LDAP), including NFSv4 with Kerberos and storage network segmentation.

• Experience scripting in Bash or Python.

• Experience with IaC and configuration management tools (Ansible, Terraform).

Preferred Skills & Experience

• Familiarity with data classification, metadata management, and at-rest encryption technologies.

• Operational knowledge of virtualization technologies and hypervisors, such as VMware ESXi/vCenter and Proxmox VE.

• Strong analytical and organizational skills.

• Excellent oral and written communication skills.

Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience. At 10x, base pay is also just one component of the Company’s total compensation package. This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company’s total compensation package.

USD 136,500-184,700 / year

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.