Scientist 1, Single Cell Assay Development

10x Genomics, Inc.; Pleasanton, Northern (CA, KY); Hybrid; USD 123,000 - 167,000; Full time

Benefits offered by this job

Equity grants

Health benefits

Annual bonus

Job summary

10x Genomics, Inc. is seeking a motivated scientist to join the Single Cell Biology group, focusing on developing and optimizing single cell assays and hands-on molecular biology work.

You will work cross-functionally in a fast-paced environment with colleagues from Molecular/Cell Biology, Chemistry, Fluidics, and Computational Biology, applying NGS expertise to troubleshoot and advance assay development.

Qualifications

• Hands-on molecular biology experience including nucleic acid extraction and PCR/qPCR.
• Strong background in NGS workflows and library preparation.
• Ability to design and troubleshoot multi-step experiments.
• Experience with data analysis to interpret results.
• Excellent collaboration and communication skills.

Responsibilities

• Develop and optimize single cell assay workflows and sample processing.
• Prepare sequencing libraries and perform data analysis.
• Troubleshoot assay components and assist internal teams and customers.
• Collaborate cross-functionally with R&D, Support, and Marketing.
• Contribute to project plans and timelines.
• Suggest new tools and methods to advance assay development.
• Interpret results to determine next steps.

Skills

Molecular biology techniques

NGS data analysis

Experiment design

PCR/qPCR

Collaboration & communication

Troubleshooting

Education

B.S./M.S./Ph.D. in chemistry or biology

Tools

NGS library preparation

Nucleic acid extraction

PCR/qPCR workflows

Bioinformatics basics

Job description

About the role:

We are seeking a motivated and driven scientist to join the Single Cell Biology group in a full-time role focused on the development and optimization of single cell assays. This role executes hands-on molecular biology work to develop, test, and refine 10x single cell workflows, and supports advanced troubleshooting for internal teams and customers.

You will work in a fast-paced, multidisciplinary environment alongside colleagues in Molecular/Cell Biology, Chemistry, Fluidics, and Computational Biology. Candidates must have hands-on experience with 10x single cell assays, a strong foundation in NGS and molecular biology techniques, and the ability to apply that knowledge to troubleshoot complex systems.

What you will be doing

• Perform standard and custom experiments to develop, test, and improve single cell assay workflows, including sample processing, library preparation, sequencing, and data analysis


• Prepare high-quality NGS libraries using established molecular biology protocols


• Contribute to the design, testing, and troubleshooting of new assay components and existing systems


• Master the use of existing tools and defined protocols, and identify opportunities to improve them


• Conceive of and develop new tools and methods to support assay development


• Analyze and interpret experimental data to draw conclusions and determine next steps


• Begin to collaborate cross-functionally with R&D, Support, and Marketing to advance assay development priorities


• Contribute to project plans and sub-task timelines for assigned workstreams

Minimum Qualifications

• B.S./M.S. or Ph.D. in chemistry, molecular biology, biochemistry, cell biology, or a related field


• B.S. with 4+ years, M.S. with 2+ years, or Ph.D. with 0-2 years of relevant biotechnology or pharmaceutical industry experience


• Hands-on experience with molecular biology techniques, including nucleic acid extraction, PCR/qPCR, and NGS library preparation


• Direct experience with Next-Generation Sequencing (NGS) workflows and standard molecular biology techniques


• Experience with experimental design and statistical data analysis


• Ability to perform complex multi-step experiments with diligent attention to planning, organization, hands-on technique, and record keeping


• Strong collaboration and communication skills, with the ability to manage competing priorities


• Desire to work in a flexible, fast-paced environment

Preferred Qualifications

• Hands-on experience running 10x single cell assays


• Experience working with challenging clinical sample types (e.g., FFPE tissue, primary tumor cells, low-input samples)


• Familiarity with the product development lifecycle, including new product introduction and formal product testing (e.g., verification and validation)

Below is the base pay range for this full-time position. The actual base pay will depend on several factors unique to each candidate, including one’s skills, qualifications, and experience. At 10x, base pay is also just one component of the Company’s total compensation package. This role is also eligible for 10x’s equity grants, its comprehensive health and retirement benefit programs, and its annual bonus program or sales incentive program. During the hiring process, your 10x recruiter can share more about the Company’s total compensation package.

Salary Range: $123,100 - $166,500

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.