Senior IT Infrastructure & Security Architect

Jobtailor; Watertown (MA); On-site; USD 150,000 - 210,000; Full time

Job summary

Jobtailor is seeking an experienced IT leader to own the strategy, design, and operation of enterprise IT infrastructure and security in a regulated life sciences context. You will oversee Microsoft 365 (IAM, Intune, Defender, Purview) and manage MSP/SOC partnerships for secure endpoints, BYOD, and cloud DevOps.

The role focuses on scaling cloud environments, data governance, and AI security policies to align with business and regulatory objectives, while ensuring compliance with SOX, GxP, FDA

Qualifications

• Bachelor’s degree in information technology, computer science, engineering, or related field; equivalent experience considered
• 10+ years of progressive IT experience in regulated life sciences, biotech, or pharmaceutical environments
• Experience supporting cloud infrastructure, digital workplace technologies, business systems, and cybersecurity controls
• Experience managing MSPs, vendors, and third‑party technology partners
• Working knowledge of SOX, GxP, FDA‑regulated environments, and NIST CSF compliance and control frameworks
• Expertise in Microsoft Azure, cloud architecture, and modern IT infrastructure
• Familiarity with AI-enabled workplace tools, governance considerations, and business-process applications
• Exceptional problem-solving skills and willingness to engage in hands-on technical support
• Excellent communication and interpersonal skills

Responsibilities

• Report to the Head of Information Technology.
• Own the strategy, design, implementation, and ongoing operations of enterprise IT infrastructure and security.
• Oversee the Microsoft 365 environment, including IAM, Intune, Defender, and Purview.
• Ensure secure endpoint configuration and management with MSP and SOC partners, covering corporate devices and BYOD.
• Architect and scale infrastructure and cloud computing environments to support company growth.
• Lead data governance efforts, including DLP, sensitivity labels, and AI security policies.
• Advance the Information Security program in alignment with business objectives and regulatory requirements.
• Work with MSPs to manage web hosting, DNS, Cloudflare, and GitHub infrastructure.
• Architect and support the cloud-based DevOps environment.
• Ensure secure home-office technology infrastructure.
• Lead implementation and optimization of cloud-based applications and infrastructure.
• Ensure infrastructure solutions comply with corporate policies, standards, and regulations.

Skills

Microsoft 365 Management

Cloud Architecture

Data Governance

Cybersecurity Controls

Regulatory Compliance

Endpoint Management

IAM

Intune

Microsoft Defender

Purview

Education

Bachelor’s degree in information technology / computer science / engineering

Tools

Azure

Cloudflare

GitHub

MSP Management

Job description

Jobtailor is seeking an experienced IT leader to own the strategy, design, and operation of enterprise IT infrastructure and security in a regulated life sciences context. You will oversee Microsoft 365 (IAM, Intune, Defender, Purview) and manage MSP/SOC partnerships for secure endpoints, BYOD, and cloud DevOps.

The role focuses on scaling cloud environments, data governance, and AI security policies to align with business and regulatory objectives, while ensuring compliance with SOX, GxP, FDA