Senior In-House CRA – Global Trials (6–9mo, Equity)

Anagram Therapeutics, Inc.; Natick (MA); On-site; USD 95,000 - 140,000; Full time

Benefits offered by this job

Equity

Medical benefits

Dental benefits

Short-term disability

Long-term disability

AD&D

401(k) retirement plan

Employee Referral Program

Job summary

Anagram Therapeutics in Natick, MA seeks a hands-on In-House, Senior Clinical Research Associate to provide sponsor-side oversight and hands-on operational support for global trials. This 6-9 month consulting role may become permanent, focusing on site performance, CRO monitoring, enrollment, data quality, and protocol compliance.

The candidate will conduct sponsor oversight, co-monitoring, remote monitoring, and site visits as needed, with up to 30-40% travel; work independently in a small

Qualifications

• Minimum 5 years CRA experience including independent site monitoring for multicenter Phase 2/3 trials.
• Experience in CRO environments; sponsor or biotech experience preferred.
• Experience using EDC, CTMS, eTMF and trial systems.
• Strong knowledge of ICH-GCP and FDA regulations; able to work independently.
• Willingness to travel domestically and internationally up to 30-40%.

Responsibilities

• Perform sponsor oversight, co-monitoring, and targeted on-site visits as needed.
• Escalate site issues, protocol deviations, and data quality concerns from a monitoring perspective.
• Assess site readiness for activation, enrollment, visits and closeout.
• Support TMF completeness and inspection readiness; ensure documentation accuracy.
• Track samples and supplies for a study.
• Provide focused support to high risk or underperforming sites.
• Onboard and train CRO CRAs for study readiness.
• Maintain trackers, documentation and status reporting for activities.
• Contribute to development/improvement of clinical operations processes and tools.
• Assist with audit and inspection readiness activities and responses to findings.

Skills

Site monitoring

CRO oversight

Data quality

Risk assessment

Independent work

Education

Bachelor’s degree in life sciences

Tools

EDC

CTMS

eTMF

Job description

Anagram Therapeutics in Natick, MA seeks a hands-on In-House, Senior Clinical Research Associate to provide sponsor-side oversight and hands-on operational support for global trials. This 6-9 month consulting role may become permanent, focusing on site performance, CRO monitoring, enrollment, data quality, and protocol compliance.

The candidate will conduct sponsor oversight, co-monitoring, remote monitoring, and site visits as needed, with up to 30-40% travel; work independently in a small