Senior High-Content Imaging Scientist

Pfizer; Groton (CT); Hybrid; USD 94,000 - 156,000; Full time

Benefits offered by this job

Relocation assistance

Comprehensive benefits package

On-site campus facilities

Job summary

Pfizer is seeking a highly motivated scientist to join the Discovery Biology and Pharmacology group at the Groton campus in Connecticut. The role focuses on high-content imaging and flow cytometry to support a diverse small molecule portfolio across therapeutic areas.

You will design and optimize imaging assays, develop analysis workflows, and translate imaging data into actionable biological insights while collaborating with chemists, structural biologists and computational scientists.

Qualifications

• PhD in molecular biology, pharmacology, cell biology, biomedical engineering, or related field with 0-4 years of work experience, plus 2+ years applying fluorescence or confocal microscopy.
• Imaging assay expertise: hands-on experience developing, optimizing, and troubleshooting high-content imaging assays; familiarity with flow cytometry assay platforms is valued.
• Experience with image-analysis and quantitative data-analysis to extract insights from imaging data.
• Experience with advanced image-analysis platforms, computational workflows, scripting, programming, or computational biology for algorithm development.

Responsibilities

• Design, develop, and optimize high-content imaging assays across projects.
• Independently troubleshoot imaging and flow cytometry assays.
• Analyze imaging data and build analysis workflows to support screening.
• Translate imaging results into clear biological insights for the team.
• Maintain imaging infrastructure and enable advanced imaging applications.
• Support screening campaigns and mechanism-of-action studies.
• Collaborate with cross-functional teams across DBP and Medicine Design.

Skills

High-content imaging

Flow cytometry

Image analysis

Programming / scripting

Scientific communication

Education

PhD in molecular biology/pharmacology/cell biology/biomedical engineering

Tools

Image analysis software

Imaging platforms

Flow cytometry platforms

Job description

Pfizer is seeking a highly motivated scientist to join the Discovery Biology and Pharmacology group at the Groton campus in Connecticut. The role focuses on high-content imaging and flow cytometry to support a diverse small molecule portfolio across therapeutic areas.

You will design and optimize imaging assays, develop analysis workflows, and translate imaging data into actionable biological insights while collaborating with chemists, structural biologists and computational scientists.